{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,5]],"date-time":"2026-10-05T06:44:12Z","timestamp":1791182652897,"version":"4.1.0"},"reference-count":27,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2019,10,18]],"date-time":"2019-10-18T00:00:00Z","timestamp":1571356800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["J Vet Emergen Crit Care"],"published-print":{"date-parts":[[2019,11]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Objective<\/jats:title><jats:p>To determine the effect of Yunnan Baiyao (YB) on hemostatic parameters measured by thromboelastography (TEG) in apparently healthy cats administered 1 capsule of YB orally twice daily for 1 week.<\/jats:p><\/jats:sec><jats:sec><jats:title>Design<\/jats:title><jats:p>Prospective study of client\u2010owned cats at a small animal specialty hospital.<\/jats:p><\/jats:sec><jats:sec><jats:title>Setting<\/jats:title><jats:p>One private referral center.<\/jats:p><\/jats:sec><jats:sec><jats:title>Animals<\/jats:title><jats:p>Twenty client\u2010owned adult cats were prospectively enrolled.<\/jats:p><\/jats:sec><jats:sec><jats:title>Interventions<\/jats:title><jats:p>All cats underwent echocardiographic examination by the same board\u2010certified cardiologist to rule out occult cardiomyopathy. Blood samples were collected for analysis of baseline CBC, fibrinogen, and kaolin\u2010activated TEG values. Cats were administered 1 capsule (250 mg\/capsule) of YB twice daily orally for 1 week and the physical examination, CBC, fibrinogen, and TEG were re\u2010evaluated. Any side effects attributed to YB were noted at this time.<\/jats:p><\/jats:sec><jats:sec><jats:title>Measurements and Main Results<\/jats:title><jats:p>Three cats were excluded as 2 cats were identified with underlying cardiomyopathy and another cat had a cystic mass in the cranial mediastinum identified via echocardiography. Seventeen cats were treated with YB; however, 1 cat could not complete the study due to severe vomiting associated with YB administration. The remaining 16 cats completed the study, although 2 additional cats experienced transient vomiting. Yunnan Baiyao administration was associated with a significant decrease in HCT and red blood cell count, although no cat became anemic. None of the TEG parameters significantly changed compared to baseline after 1 week of YB therapy.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>The results of this study suggest YB at a dose of 1 capsule orally twice daily in cats fails to produce any significant change in hemostatic parameters as measured by TEG, although it did significantly reduce HCT and red blood cell count. Yunnan Baiyao was tolerated for most of the cats, although 3 of 17 (17.6%) cats experienced vomiting. Clinicians should be aware of these effects before considering the use of YB in cats.<\/jats:p><\/jats:sec>","DOI":"10.1111\/vec.12895","type":"journal-article","created":{"date-parts":[[2019,10,18]],"date-time":"2019-10-18T10:10:07Z","timestamp":1571393407000},"page":"611-615","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":9,"title":["A prospective evaluation of oral Yunnan Baiyao therapy on thromboelastographic parameters in apparently healthy cats"],"prefix":"10.1111","volume":"29","author":[{"given":"Jeffrey E.","family":"Patlogar","sequence":"first","affiliation":[{"name":"From Inland Valley Veterinary Specialists and Emergency Services  Upland California"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Colleen","family":"Tansey","sequence":"additional","affiliation":[{"name":"From Inland Valley Veterinary Specialists and Emergency Services  Upland California"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Melissa","family":"Wiebe","sequence":"additional","affiliation":[{"name":"From Inland Valley Veterinary Specialists and Emergency Services  Upland California"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gabrielle C.","family":"Hybki","sequence":"additional","affiliation":[{"name":"Veterinary Specialty Center  Buffalo Grove Illinois"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Todd","family":"Trostel","sequence":"additional","affiliation":[{"name":"From Inland Valley Veterinary Specialists and Emergency Services  Upland California"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4153-5426","authenticated-orcid":false,"given":"Lisa A.","family":"Murphy","sequence":"additional","affiliation":[{"name":"Orange County Veterinary Specialists  Tustin 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