{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,1]],"date-time":"2025-10-01T16:27:18Z","timestamp":1759336038276,"version":"3.40.5"},"reference-count":28,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2019,12,17]],"date-time":"2019-12-17T00:00:00Z","timestamp":1576540800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"name":"The Basic Science Research Program through the National Research Foundation of Korea (NRF) funded by the Ministry of Education","award":["NRF-2014R1A1A4A01007297"],"award-info":[{"award-number":["NRF-2014R1A1A4A01007297"]}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["J Vet Emergen Crit Care"],"published-print":{"date-parts":[[2020,1]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Objective<\/jats:title><jats:p>To examine the extent to which rapid thromboelastography (r\u2010TEG) could decrease the testing time in comparison with that required for kaolin\u2010activated thromboelastography (TEG), and to compare 2 types of blood samples (ie, native and citrated whole blood [WB]), for determining r\u2010TEG values in healthy dogs.<\/jats:p><\/jats:sec><jats:sec><jats:title>Design<\/jats:title><jats:p>Prospective observational study.<\/jats:p><\/jats:sec><jats:sec><jats:title>Setting<\/jats:title><jats:p>University teaching hospital.<\/jats:p><\/jats:sec><jats:sec><jats:title>Animals<\/jats:title><jats:p>Sixteen healthy Beagles.<\/jats:p><\/jats:sec><jats:sec><jats:title>Interventions<\/jats:title><jats:p>Kaolin\u2010activated TEG test using citrated WB samples and r\u2010TEG test using native and citrated WB samples were performed in 16 dogs. At 60 minutes after the initial blood sampling, further samples were collected from a subset of 6 dogs in the same manner to evaluate intraindividual repeatability of r\u2010TEG.<\/jats:p><\/jats:sec><jats:sec><jats:title>Measurements and Main Results<\/jats:title><jats:p>The mean time to maximum amplitude (MA) for r\u2010TEG with native and citrated WB samples was recorded as 1313.9 \u00b1 250.9 seconds and 1351.3 \u00b1 264.6 seconds (mean \u00b1 SD), respectively, and 1779.9 \u00b1 197.0 seconds for kaolin\u2010activated TEG. Coefficients of variation with native and citrated WB samples for r\u2010TEG values, TEG\u2010activated clotting time, clot formation time, \u03b1 angle, and MA, were determined to be 13.4% versus 18.8%, 11.1% versus 16.6%, 4.2% versus 5.1%, and 10.0% versus 10.0%, respectively. Intraindividual variations were lower for native WB samples than for citrated WB samples.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>The r\u2010TEG test significantly decreased the mean time to MA compared with the kaolin\u2010activated TEG test. In addition, native WB samples showed lower coefficients of variation and intraindividual variation than citrated WB samples in r\u2010TEG analysis; this suggests that native WB samples can provide more consistent results. Therefore, the r\u2010TEG method using native WB samples is recommended for assessment of dogs\u2019 hemostatic status when an early diagnosis is required.<\/jats:p><\/jats:sec>","DOI":"10.1111\/vec.12907","type":"journal-article","created":{"date-parts":[[2019,12,17]],"date-time":"2019-12-17T08:19:01Z","timestamp":1576570741000},"page":"54-59","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Comparison of native and citrated whole blood samples for rapid thromboelastography in Beagles"],"prefix":"10.1111","volume":"30","author":[{"given":"Hyebin","family":"Wang","sequence":"first","affiliation":[{"name":"Laboratory of Veterinary Internal Medicine, College of Veterinary Medicine Chungnam National University  Daejeon South Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Aryung","family":"Nam","sequence":"additional","affiliation":[{"name":"Department of Veterinary Internal Medicine, College of 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