{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,5,14]],"date-time":"2025-05-14T02:07:58Z","timestamp":1747188478373,"version":"3.40.5"},"reference-count":46,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2020,2,24]],"date-time":"2020-02-24T00:00:00Z","timestamp":1582502400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["J Vet Emergen Crit Care"],"published-print":{"date-parts":[[2020,5]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Objective<\/jats:title><jats:p>To describe the clinical presentation and medical management of a cat with perinephric abscessation and urosepsis following urethral obstruction and catheterization.<\/jats:p><\/jats:sec><jats:sec><jats:title>Case Summary<\/jats:title><jats:p>A 2\u2010year\u2010old intact male domestic shorthaired cat presented to an emergency and referral center for lethargy, vomiting, and hematuria. Severe azotemia and hyperkalemia were observed on a serum biochemistry panel. The patient was diagnosed with urethral obstruction and was treated with urethral catheterization, calcium gluconate, IV fluid therapy, buprenorphine, and prazosin. The patient's azotemia improved, and the hyperkalemia resolved. Urinary catheterization was discontinued. The patient developed pyrexia, worsening azotemia, hypoalbuminemia, hyperbilirubinemia, and dysuria. Urethral catheterization was repeated. Abdominal radiographs showed left renomegaly, and abdominal ultrasound revealed left perinephric fluid. Ultrasound\u2010guided centesis of the perinephric fluid revealed septic inflammation, and the sample was consistent with urine based upon sample creatinine. Fluid from the perinephric abscess and urine from the bladder both grew<jats:italic>Pasturella<\/jats:italic>spp. The patient was treated with perinephric catheterization, saline lavage, and a continuous infusion of cefotaxime for 72\u00a0h. The patient's azotemia quickly resolved, and the patient was discharged after 6 days of hospitalization. The patient was reported to have made a full recovery.<\/jats:p><\/jats:sec><jats:sec><jats:title>New or Unique Information Provided<\/jats:title><jats:p>This is the first described case of perinephric abscess and urosepsis following urethral obstruction in a cat and its successful medical management. Perinephric abscess not associated with intrarenal abscess has not previously been identified. Additionally, continuous antimicrobial infusion to treat overwhelming infection and the use of the RapidBac Vet immunoassay for point\u2010of\u2010care detection of urinary tract infection has not been described in cats.<\/jats:p><\/jats:sec>","DOI":"10.1111\/vec.12946","type":"journal-article","created":{"date-parts":[[2020,2,25]],"date-time":"2020-02-25T05:55:19Z","timestamp":1582610119000},"page":"318-324","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Successful medical management of perinephric abscess and urosepsis following urethral obstruction in a cat"],"prefix":"10.1111","volume":"30","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-7179-0287","authenticated-orcid":false,"given":"Christopher L.","family":"Norkus","sequence":"first","affiliation":[{"name":"Allegheny Veterinary Emergency Trauma &amp; Specialty Monroeville PA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Iain","family":"Keir","sequence":"additional","affiliation":[{"name":"Allegheny Veterinary Emergency Trauma &amp; Specialty Monroeville PA"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2020,2,24]]},"reference":[{"key":"e_1_2_5_2_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1939-1676.2004.tb02640.x"},{"key":"e_1_2_5_3_1","doi-asserted-by":"publisher","DOI":"10.1177\/1098612X15613388"},{"key":"e_1_2_5_4_1","doi-asserted-by":"publisher","DOI":"10.3349\/ymj.2010.51.4.569"},{"key":"e_1_2_5_5_1","doi-asserted-by":"publisher","DOI":"10.3904\/kjim.2008.23.3.140"},{"key":"e_1_2_5_6_1","first-page":"61","article-title":"Diagnosis and treatment of a perirenal abscess in a dog","volume":"39","author":"Cabassu J","year":"2008","journal-title":"Point Veterinaire"},{"key":"e_1_2_5_7_1","doi-asserted-by":"publisher","DOI":"10.1136\/vr.154.18.562"},{"key":"e_1_2_5_8_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1748-5827.2003.tb00097.x"},{"key":"e_1_2_5_9_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1751-0813.1963.tb04274.x"},{"key":"e_1_2_5_10_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1751-0813.1988.tb14304.x"},{"key":"e_1_2_5_11_1","doi-asserted-by":"publisher","DOI":"10.1111\/vru.12259"},{"key":"e_1_2_5_12_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1740-8261.2007.00300.x"},{"key":"e_1_2_5_13_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1748-5827.2006.00204.x"},{"key":"e_1_2_5_14_1","doi-asserted-by":"publisher","DOI":"10.2460\/javma.2000.217.531"},{"key":"e_1_2_5_15_1","doi-asserted-by":"publisher","DOI":"10.2460\/javma.238.7.890"},{"key":"e_1_2_5_16_1","doi-asserted-by":"publisher","DOI":"10.2460\/javma.2004.225.897"},{"key":"e_1_2_5_17_1","doi-asserted-by":"publisher","DOI":"10.1002\/hep.21480"},{"key":"e_1_2_5_18_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0720-048X(02)00156-0"},{"key":"e_1_2_5_19_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00268-006-0162-x"},{"key":"e_1_2_5_20_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0022-5347(05)64443-6"},{"key":"e_1_2_5_21_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0022-5347(01)66536-4"},{"key":"e_1_2_5_22_1","doi-asserted-by":"publisher","DOI":"10.1089\/cren.2017.0067"},{"key":"e_1_2_5_23_1","first-page":"w14368","article-title":"Prolonged administration of \u03b2\u2010lactam antibiotics \u2010 a comprehensive review and critical appraisal","volume":"146","author":"Osthoff M","year":"2016","journal-title":"Swiss Med Wkly"},{"key":"e_1_2_5_24_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00134-015-4188-0"},{"key":"e_1_2_5_25_1","doi-asserted-by":"publisher","DOI":"10.1093\/cid\/cis856"},{"key":"e_1_2_5_26_1","doi-asserted-by":"publisher","DOI":"10.1111\/vec.12583"},{"key":"e_1_2_5_27_1","doi-asserted-by":"publisher","DOI":"10.1097\/01.CCM.0000217961.75225.E9"},{"issue":"1","key":"e_1_2_5_28_1","first-page":"86","article-title":"Pharmacokinetics of cefotaxime in the domestic cat","volume":"47","author":"McElroy D","year":"1986","journal-title":"Am J Vet Res"},{"key":"e_1_2_5_29_1","doi-asserted-by":"publisher","DOI":"10.1177\/1098612X13477414"},{"key":"e_1_2_5_30_1","doi-asserted-by":"publisher","DOI":"10.2460\/javma.2004.224.1936"},{"key":"e_1_2_5_31_1","doi-asserted-by":"publisher","DOI":"10.1136\/vr.102630"},{"issue":"4","key":"e_1_2_5_32_1","first-page":"227","article-title":"Urinary tract infections in cats. 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