{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,9]],"date-time":"2026-01-09T00:31:37Z","timestamp":1767918697807,"version":"3.49.0"},"reference-count":38,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2020,7,10]],"date-time":"2020-07-10T00:00:00Z","timestamp":1594339200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["J Vet Emergen Crit Care"],"published-print":{"date-parts":[[2020,9]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Objective<\/jats:title><jats:p>To evaluate the effect of 5\u00a0cm H<jats:sub>2<\/jats:sub>O of continuous positive airway pressure (CPAP) on laryngeal size in spontaneously breathing anesthetized dogs via computed tomography (CT).<\/jats:p><\/jats:sec><jats:sec><jats:title>Design<\/jats:title><jats:p>Prospective, randomized, cross\u2010over clinical study.<\/jats:p><\/jats:sec><jats:sec><jats:title>Setting<\/jats:title><jats:p>University teaching hospital and referral private practice.<\/jats:p><\/jats:sec><jats:sec><jats:title>Animals<\/jats:title><jats:p>Eight healthy client\u2010owned dogs undergoing CT.<\/jats:p><\/jats:sec><jats:sec><jats:title>Interventions<\/jats:title><jats:p>Dogs were sedated with acepromazine 20 \u03bcg\/kg IM and induced with fentanyl 2 \u03bcg\/kg and propofol 3\u20135\u00a0mg\/kg IV before being maintained on fentanyl (5 \u03bcg\/kg\/h) and propofol (0.3\u00a0mg\/kg\/min) constant rate infusion. Dogs received an air\/oxygen mixture with (CPAP) and without (NO\u2010CPAP) 5\u00a0cm H<jats:sub>2<\/jats:sub>O of CPAP in a random order. Each study step lasted 15 minutes.<\/jats:p><\/jats:sec><jats:sec><jats:title>Measurements and Main Results<\/jats:title><jats:p>Ten minutes after the beginning of each study period, a CT scan of the laryngeal region was obtained at end\u2010expiration. CT images were analyzed to determine the laryngeal cross\u2010sectional area (CSA; cm<jats:sup>2<\/jats:sup>), total volume (<jats:italic>V<\/jats:italic><jats:sub>TOT<\/jats:sub>; cm<jats:sup>3<\/jats:sup>), and laterolateral and dorsoventral diameters (<jats:italic>D<\/jats:italic><jats:sub>LL<\/jats:sub> and <jats:italic>D<\/jats:italic><jats:sub>DV<\/jats:sub>, respectively; cm). Differences between the 2 treatments were analyzed with <jats:italic>t<\/jats:italic>\u2010test for paired data (<jats:italic>P<\/jats:italic>\u00a0&lt; 0.05). Compared to the NO\u2010CPAP, during CPAP the CSA increased by 53.3 \u00b1 23.1% (ie, from 3.3 \u00b1 0.8 to 5.1 \u00b1 1.3 cm<jats:sup>2<\/jats:sup>, <jats:italic>P<\/jats:italic>\u00a0= 0.0004), <jats:italic>V<\/jats:italic><jats:sub>TOT<\/jats:sub> increased by 52.4 \u00b1 13.6% (from 6.2 \u00b1 1.7 to 9.4 \u00b1 2.4 cm<jats:sup>3<\/jats:sup>, <jats:italic>P<\/jats:italic>\u00a0&lt; 0.0001), and <jats:italic>D<\/jats:italic><jats:sub>LL<\/jats:sub> and <jats:italic>D<\/jats:italic><jats:sub>DV<\/jats:sub> were 55.5 \u00b1 13.3% (3.6\u00a0\u00b1 0.8 vs 2.4 \u00b1 0.5\u00a0cm, <jats:italic>P<\/jats:italic>\u00a0= 0.006) and 20.3 \u00b1 8.8% larger (3.2 \u00b1 0.7 vs 2.7 \u00b1 0.6\u00a0cm, <jats:italic>P<\/jats:italic>\u00a0=\u00a00.0002), respectively.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>Laryngeal volume and cross sectional area increased during the application of 5\u00a0cm H<jats:sub>2<\/jats:sub>O of helmet CPAP in spontaneously breathing anesthetized dogs.<\/jats:p><\/jats:sec>","DOI":"10.1111\/vec.12977","type":"journal-article","created":{"date-parts":[[2020,7,10]],"date-time":"2020-07-10T14:29:15Z","timestamp":1594391355000},"page":"543-549","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":8,"title":["Evaluation of the effects of helmet continuous positive airway pressure on laryngeal size in dogs anesthetized with propofol and fentanyl using computed tomography"],"prefix":"10.1111","volume":"30","author":[{"given":"Vincenzo","family":"Rondelli","sequence":"first","affiliation":[{"name":"Istituto Veterinario di Novara  Novara Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Alessandro","family":"Guarracino","sequence":"additional","affiliation":[{"name":"Section of Veterinary Clinics and Animal Production, Department of Emergency and Organ Transplants University of Bari Aldo Moro  Bari 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