{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,10]],"date-time":"2026-02-10T18:31:21Z","timestamp":1770748281843,"version":"3.49.0"},"reference-count":13,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2020,8,11]],"date-time":"2020-08-11T00:00:00Z","timestamp":1597104000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["J Vet Emergen Crit Care"],"published-print":{"date-parts":[[2020,9]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Objective<\/jats:title><jats:p>To describe patient recovery in dogs that had undergone mechanical ventilation (MV) and received atracurium as a continuous rate infusion (CRI).<\/jats:p><\/jats:sec><jats:sec><jats:title>Case series summary<\/jats:title><jats:p>Three dogs were treated with atracurium CRI while mechanically ventilated and were successfully weaned. All were pediatric patients (2\u20103 months old) ventilated due to respiratory fatigue and hypoxemia. All dogs experienced seizure activity in the initial 24\u00a0h following extubation and were treated with various anticonvulsant protocols; no patients experienced documented seizures after 48\u00a0h of discontinuation from MV.<\/jats:p><\/jats:sec><jats:sec><jats:title>New or unique information provided<\/jats:title><jats:p>All three successfully weaned dogs that had received an atracurium CRI experienced new onset seizures in their recovery from MV. Atracurium use in long\u2010term MV has not been described previously, and seizures in dogs following atracurium administration has not been described in the clinical setting. Although causation cannot be proven in this case series, atracurium use should be carefully considered and be monitored appropriately when used for a prolonged duration.<\/jats:p><\/jats:sec>","DOI":"10.1111\/vec.12989","type":"journal-article","created":{"date-parts":[[2020,8,12]],"date-time":"2020-08-12T02:53:43Z","timestamp":1597200823000},"page":"592-596","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":6,"title":["Seizure activity following atracurium continuous rate infusion in three mechanically ventilated juvenile dogs"],"prefix":"10.1111","volume":"30","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-8774-2493","authenticated-orcid":false,"given":"Rebekah E","family":"Donaldson","sequence":"first","affiliation":[{"name":"Department of Clinical Science and Services The Royal Veterinary College  North Mymms Hertfordshire UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Stefano","family":"Cortellini","sequence":"additional","affiliation":[{"name":"Department of Clinical Science and Services The Royal Veterinary College  North Mymms Hertfordshire UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Karen","family":"Humm","sequence":"additional","affiliation":[{"name":"Department of Clinical Science and Services The Royal Veterinary College  North Mymms Hertfordshire UK"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2020,8,11]]},"reference":[{"key":"e_1_2_9_2_1","doi-asserted-by":"publisher","DOI":"10.1093\/bja\/85.6.850"},{"key":"e_1_2_9_3_1","doi-asserted-by":"publisher","DOI":"10.1017\/S0265021502000777"},{"key":"e_1_2_9_4_1","doi-asserted-by":"publisher","DOI":"10.1097\/00000542-198607000-00009"},{"key":"e_1_2_9_5_1","doi-asserted-by":"publisher","DOI":"10.1080\/08998280.2017.1416237"},{"key":"e_1_2_9_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.vaa.2018.03.002"},{"key":"e_1_2_9_7_1","doi-asserted-by":"publisher","DOI":"10.1152\/jn.00796.2014"},{"key":"e_1_2_9_8_1","doi-asserted-by":"publisher","DOI":"10.5326\/15473317-32-4-365"},{"key":"e_1_2_9_9_1","doi-asserted-by":"publisher","DOI":"10.2460\/javma.230.1.64"},{"key":"e_1_2_9_10_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1476-4431.2011.00635.x"},{"key":"e_1_2_9_11_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1476-4431.2011.00669.x"},{"key":"e_1_2_9_12_1","doi-asserted-by":"publisher","DOI":"10.1111\/vec.12230"},{"key":"e_1_2_9_13_1","doi-asserted-by":"publisher","DOI":"10.1097\/CCM.0000000000002255"},{"key":"e_1_2_9_14_1","first-page":"124","volume-title":"Plumb's Veterinary Drug Handbook","author":"Plumb DC","year":"2015"}],"container-title":["Journal of Veterinary Emergency and Critical Care"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fvec.12989","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/vec.12989","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1111\/vec.12989","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/vec.12989","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,9,5]],"date-time":"2023-09-05T20:17:08Z","timestamp":1693945028000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/vec.12989"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,8,11]]},"references-count":13,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2020,9]]}},"alternative-id":["10.1111\/vec.12989"],"URL":"https:\/\/doi.org\/10.1111\/vec.12989","archive":["Portico"],"relation":{},"ISSN":["1479-3261","1476-4431"],"issn-type":[{"value":"1479-3261","type":"print"},{"value":"1476-4431","type":"electronic"}],"subject":[],"published":{"date-parts":[[2020,8,11]]},"assertion":[{"value":"2018-10-17","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2019-04-01","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2020-08-11","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}