{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,25]],"date-time":"2026-07-25T20:02:28Z","timestamp":1785009748524,"version":"3.55.0"},"reference-count":24,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2021,5,5]],"date-time":"2021-05-05T00:00:00Z","timestamp":1620172800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["J Vet Emergen Crit Care"],"published-print":{"date-parts":[[2021,7]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Objective<\/jats:title><jats:p>To describe a case of Waterhouse\u2013Friderichsen syndrome of adrenocortical failure in a cat with <jats:italic>Klebsiella<\/jats:italic> spp. infection.<\/jats:p><\/jats:sec><jats:sec><jats:title>Case Summary<\/jats:title><jats:p>A 12\u2010year\u2010old male neutered domestic short\u2010haired cat was referred for respiratory failure requiring mechanical ventilation. The cat remained comatose despite successful weaning from the ventilator and developed a <jats:italic>Klebsiella pneumoniae<\/jats:italic> pneumonia. On day 4 of hospitalization, the cat acutely deteriorated with profound hypotension, azotemia, and hyperkalemia, which rapidly progressed to cardiac arrest. Necropsy findings revealed massive adrenal hemorrhage and intralesional bacteria, termed Waterhouse\u2013Friderichsen syndrome. Waterhouse\u2013Friderichsen syndrome was suspected to have been the cause of acquired adrenocortical insufficiency and sudden death of the cat.<\/jats:p><\/jats:sec><jats:sec><jats:title>New or Unique Information<\/jats:title><jats:p>To the authors\u2019 knowledge, this is the first report of sepsis causing Waterhouse\u2013Friderichsen syndrome in a veterinary species.<\/jats:p><\/jats:sec>","DOI":"10.1111\/vec.13063","type":"journal-article","created":{"date-parts":[[2021,5,5]],"date-time":"2021-05-05T10:20:44Z","timestamp":1620210044000},"page":"531-536","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":3,"title":["Waterhouse\u2013Friderichsen syndrome in a cat with <i>Klebsiella<\/i> spp. infection"],"prefix":"10.1111","volume":"31","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-5865-2181","authenticated-orcid":false,"given":"Laura P.","family":"Cole","sequence":"first","affiliation":[{"name":"Department of Clinical 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