{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,18]],"date-time":"2026-08-18T01:22:55Z","timestamp":1787016175536,"version":"build-2736575974"},"reference-count":35,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2021,8,21]],"date-time":"2021-08-21T00:00:00Z","timestamp":1629504000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["J Vet Emergen Crit Care"],"published-print":{"date-parts":[[2022,1]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Objective<\/jats:title>\n                    <jats:p>To assess the prognostic utility of admission quick Sequential Organ Failure Assessment (qSOFA) scores for in\u2010hospital mortality in a population of dogs with surgically treated sepsis.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Design<\/jats:title>\n                    <jats:p>Retrospective cohort study of dogs from January 2011 to January 2018.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Setting<\/jats:title>\n                    <jats:p>University teaching hospital.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Animals<\/jats:title>\n                    <jats:p>One thousand three hundred nine cases were identified with a clinical diagnosis of sepsis requiring surgical source control. Two hundred and four dogs with surgically treated sepsis met inclusion criteria, defined as: meeting 2 or more systemic inflammatory response syndrome (SIRS) criteria with a documented source of infection. One hundred and forty\u2010three cases of septic peritonitis, 26 cases of septic soft tissue infection, 20 cases of pyometra, and 15 cases of pyothorax were evaluated.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Interventions<\/jats:title>\n                    <jats:p>None.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Measurements and main results<\/jats:title>\n                    <jats:p>\n                      Overall in\u2010hospital mortality was 63 of 204 (30.9%). Patients with a qSOFA\u00a0\u2265\u00a02 were more likely to die or be euthanized (odds ratio [OR] 7.1, 95% confidence interval [CI] 2.9\u201016.4;\n                      <jats:italic>P\u00a0<\/jats:italic>\n                      &lt;\u00a00.0001). Survivor and nonsurvivor qSOFA scores were significantly different in all categories. Dogs with septic peritonitis and a qSOFA\u00a0\u2265\u00a02 had an increased risk of postoperative complications (OR 3.9; 95% CI 1.3\u201011.1;\n                      <jats:italic>P\u00a0<\/jats:italic>\n                      =\u00a00.02). qSOFA scores were correlated with length of hospitalization in survivors of all\u2010cause surgical sepsis (\n                      <jats:italic>r<\/jats:italic>\n                      \u00a0=\u00a00.28,\n                      <jats:italic>P\u00a0<\/jats:italic>\n                      =\u00a00.0007), septic peritonitis (\n                      <jats:italic>r<\/jats:italic>\n                      \u00a0=\u00a00.33,\n                      <jats:italic>P\u00a0<\/jats:italic>\n                      =\u00a00.001), and septic soft tissue infection (\n                      <jats:italic>r<\/jats:italic>\n                      \u00a0=\u00a00.59,\n                      <jats:italic>P\u00a0<\/jats:italic>\n                      =\u00a00.004).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>This was the first study to retrospectively evaluate the prognostic utility of qSOFA scores in dogs surgically treated for sepsis. Dogs diagnosed with septic peritonitis and other causes of surgically treated sepsis with a qSOFA\u00a0\u2265\u00a02 may have a higher risk of in\u2010hospital mortality, although future prospective studies are necessary.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/vec.13101","type":"journal-article","created":{"date-parts":[[2021,8,21]],"date-time":"2021-08-21T16:20:29Z","timestamp":1629562829000},"page":"68-74","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":14,"title":["Retrospective evaluation of the prognostic utility of quick sequential organ failure assessment scores in dogs with surgically treated sepsis (2011\u20102018): 204 cases"],"prefix":"10.1111","volume":"32","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-2048-5848","authenticated-orcid":false,"given":"Tereza","family":"Stastny","sequence":"first","affiliation":[{"name":"Small Animal Clinical Sciences Michigan State University, College of Veterinary Medicine  East Lansing Michigan USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Amy M.","family":"Koenigshof","sequence":"additional","affiliation":[{"name":"Small Animal Clinical Sciences Michigan State University, College of Veterinary Medicine  East Lansing Michigan USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Glenn E.","family":"Brado","sequence":"additional","affiliation":[{"name":"Small Animal Clinical Sciences Michigan State University, College of Veterinary Medicine  East Lansing Michigan USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Elton K.","family":"Chan","sequence":"additional","affiliation":[{"name":"Small Animal Clinical Sciences Michigan State University, College of Veterinary Medicine  East Lansing Michigan USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nyssa A.","family":"Levy","sequence":"additional","affiliation":[{"name":"Small Animal Clinical Sciences Michigan 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