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After 3 days of mechanical ventilatory support, the cat would initiate breaths but failed weaning due to persistent hypercapnia. Following administration of intravenous caffeine (total 12\u00a0mg\/kg over 24\u00a0h), respiratory and mental status rapidly improved. The cat was subsequently extubated and able to maintain Pv<jats:sc>co<\/jats:sc><jats:sub>2<\/jats:sub>\u00a0&lt;\u00a050\u00a0mm\u00a0Hg. The cat was later diagnosed with myasthenia gravis. Quality of life 13 months after discharge was reported as excellent by her owner.<\/jats:p><\/jats:sec><jats:sec><jats:title>New or unique information provided<\/jats:title><jats:p>Caffeine may be considered as a respiratory stimulant in cats with hypoventilation.<\/jats:p><\/jats:sec>","DOI":"10.1111\/vec.13174","type":"journal-article","created":{"date-parts":[[2022,2,25]],"date-time":"2022-02-25T07:30:43Z","timestamp":1645774243000},"page":"520-523","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["The use of caffeine as a respiratory stimulant in a cat"],"prefix":"10.1111","volume":"32","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-0494-5947","authenticated-orcid":false,"given":"Christopher R.","family":"Kennedy","sequence":"first","affiliation":[{"name":"Foster Hospital for Small Animals Cummings School of Veterinary Medicine at Tufts University  North Grafton Massachusetts 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