{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,12]],"date-time":"2026-01-12T23:59:31Z","timestamp":1768262371371,"version":"3.49.0"},"reference-count":25,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2022,8,12]],"date-time":"2022-08-12T00:00:00Z","timestamp":1660262400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["J Vet Emergen Crit Care"],"published-print":{"date-parts":[[2022,11]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Objective<\/jats:title><jats:p>To describe the clinical signs, clinical course, and prognosis of suspected left atrial rupture (LAR) secondary to myxomatous mitral valve disease (MMVD) in dogs and to compare them with dogs with suspected neoplastic cardiac tamponade (NCT).<\/jats:p><\/jats:sec><jats:sec><jats:title>Design<\/jats:title><jats:p>Retrospective study from November 2015 to October 2019<\/jats:p><\/jats:sec><jats:sec><jats:title>Setting<\/jats:title><jats:p>An out\u2010of\u2010hours Emergency Animal Hospital.<\/jats:p><\/jats:sec><jats:sec><jats:title>Animals<\/jats:title><jats:p>Twenty\u2010three dogs with LAR secondary to MMVD (LAR group) and 47 dogs with NCT (NCT group).<\/jats:p><\/jats:sec><jats:sec><jats:title>Interventions<\/jats:title><jats:p>None.<\/jats:p><\/jats:sec><jats:sec><jats:title>Measurements and Main Results<\/jats:title><jats:p>The following were the characteristics of the study population (LAR group vs NCT groups) with <jats:italic>P<\/jats:italic>\u00a0&lt;\u00a00.05 as the significance threshold: male sex, 83%\u00a0vs 66%; median age, 11.9 vs 12.5 years; and median weight, 3.8 vs 6.4\u00a0kg (<jats:italic>P<\/jats:italic>\u00a0&lt;\u00a00.001). Chihuahuas and Miniature Dachshunds were overrepresented in the LAR and NCT groups, respectively. Statistically different clinical findings between the 2 groups were as follows (LAR vs NCT): pulmonary edema, 43%\u00a0vs 0%; pericardial thrombus, 70%\u00a0vs 6% (<jats:italic>P<\/jats:italic>\u00a0&lt;\u00a00.001); ineffectiveness of pericardiocentesis (whether aspiration of pericardial fluid was successful or not), 58%\u00a0vs 2% (<jats:italic>P<\/jats:italic>\u00a0&lt;\u00a00.001); mortality rate within 48\u00a0hours of visiting hospital, 35%\u00a0vs 9% (<jats:italic>P<\/jats:italic>\u00a0&lt;\u00a00.01). No significant difference was observed in survival time after discharge between the 2 groups.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>The proportion of dogs with a diagnosis of LAR secondary to MMVD in dogs with cardiac tamponade was higher than the previously reported rate. Furthermore, the frequency of pulmonary edema, ineffectiveness of pericardiocentesis, and short\u2010term mortality rate was higher in the LAR group than in the NCT group.<\/jats:p><\/jats:sec>","DOI":"10.1111\/vec.13236","type":"journal-article","created":{"date-parts":[[2022,8,12]],"date-time":"2022-08-12T13:35:05Z","timestamp":1660311305000},"page":"784-790","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":4,"title":["Retrospective evaluation of clinical signs, clinical course, and prognosis between dogs with left atrial rupture secondary to myxomatous mitral valve disease and those with neoplastic cardiac tamponade (2015\u20132019): 70 cases"],"prefix":"10.1111","volume":"32","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-4815-8651","authenticated-orcid":false,"given":"Hiroaki","family":"Sugiura","sequence":"first","affiliation":[{"name":"DVMs Animal Medical Center Yokohama  Yokohama Kanagawa 224\u20100044 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