{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,28]],"date-time":"2025-10-28T11:00:14Z","timestamp":1761649214326,"version":"3.40.5"},"reference-count":24,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2023,8,14]],"date-time":"2023-08-14T00:00:00Z","timestamp":1691971200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["J Vet Emergen Crit Care"],"published-print":{"date-parts":[[2023,9]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Objective<\/jats:title><jats:p>To report the possible occurrence of dilated cardiomyopathy phenotype associated with atypical hypoadrenocorticism and subsequent marked improvement with treatment in a mixed breed dog.<\/jats:p><\/jats:sec><jats:sec><jats:title>Case Summary<\/jats:title><jats:p>A 4.5\u2010year\u2010old, neutered male mixed breed dog was evaluated for a history and clinicopathological changes consistent with atypical hypoadrenocorticism. The dog was being fed a grain\u2010free diet. While hospitalized for supportive care and diagnostics, the patient developed and was diagnosed with biventricular congestive heart failure secondary to dilated cardiomyopathy phenotype and IV fluid administration. The left\u2010sided congestive heart failure resolved with discontinuation of IV fluid therapy and short\u2010term administration of diuretics. After treatment of atypical hypoadrenocorticism with glucocorticoid supplementation, and while continuing to be fed varying grain\u2010free diets, the patient's dilated cardiomyopathy phenotype largely resolved. The patient fully recovered and did not require any long\u2010term cardiac medications.<\/jats:p><\/jats:sec><jats:sec><jats:title>New or Unique Information Provided<\/jats:title><jats:p>Development of dilated cardiomyopathy phenotype has not been described in dogs as a sequela of untreated hypoadrenocorticism but has been reported in human literature. Given the fact that standard management of hypoadrenocorticism typically involves aggressive fluid resuscitation, awareness of this potential sequela is important for patients that fail to respond or develop signs consistent with volume overload.<\/jats:p><\/jats:sec>","DOI":"10.1111\/vec.13321","type":"journal-article","created":{"date-parts":[[2023,8,14]],"date-time":"2023-08-14T09:50:18Z","timestamp":1692006618000},"page":"606-612","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Possible development and resolution of dilated cardiomyopathy phenotype secondary to atypical hypoadrenocorticism in a dog"],"prefix":"10.1111","volume":"33","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-2211-8056","authenticated-orcid":false,"given":"Alexandra H.","family":"Riggs","sequence":"first","affiliation":[{"name":"Department of Veterinary Clinical Sciences The Ohio State University  Columbus Ohio USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jaylyn","family":"Rhinehart","sequence":"additional","affiliation":[{"name":"Department of Veterinary Clinical Sciences The Ohio State University  Columbus Ohio USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5895-1181","authenticated-orcid":false,"given":"Edward S.","family":"Cooper","sequence":"additional","affiliation":[{"name":"Department of Veterinary Clinical Sciences The Ohio State University  Columbus Ohio USA"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2023,8,14]]},"reference":[{"key":"e_1_2_6_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/B978-1-4557-4456-5.00012-2"},{"key":"e_1_2_6_3_1","first-page":"380","volume-title":"Small Animal Critical Care","author":"Burkitt Creedon JM","year":"2014"},{"key":"e_1_2_6_4_1","first-page":"1","article-title":"Management of hypoadrenocorticism (Addison's disease in dogs)","volume":"9","author":"Lathan P","year":"2018","journal-title":"Vet Med"},{"key":"e_1_2_6_5_1","doi-asserted-by":"publisher","DOI":"10.1515\/JPEM.2003.16.8.1191"},{"key":"e_1_2_6_6_1","first-page":"1","article-title":"Addison's disease and dilated cardiomyopathy: a case report and review of the literature","volume":"2016","author":"Mozolevska V","year":"2016","journal-title":"Case Rep Cardiol"},{"key":"e_1_2_6_7_1","doi-asserted-by":"publisher","DOI":"10.1186\/s13256-018-1899-1"},{"key":"e_1_2_6_8_1","doi-asserted-by":"publisher","DOI":"10.1007\/BF01712167"},{"key":"e_1_2_6_9_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijcard.2006.07.207"},{"key":"e_1_2_6_10_1","doi-asserted-by":"publisher","DOI":"10.1097\/MAT.0000000000000001"},{"issue":"3","key":"e_1_2_6_11_1","first-page":"377","article-title":"Reversible cardiomyopathy associated with Addison's disease","volume":"16","author":"Afzal A","year":"2000","journal-title":"Can J Cardiol"},{"key":"e_1_2_6_12_1","doi-asserted-by":"publisher","DOI":"10.1292\/jvms.19-0240"},{"key":"e_1_2_6_13_1","doi-asserted-by":"publisher","DOI":"10.2460\/ajvr.2002.63.994"},{"key":"e_1_2_6_14_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.tvjl.2007.03.024"},{"key":"e_1_2_6_15_1","doi-asserted-by":"publisher","DOI":"10.1111\/jvim.15562"},{"key":"e_1_2_6_16_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1439-0442.1996.tb00456.x"},{"key":"e_1_2_6_17_1","doi-asserted-by":"publisher","DOI":"10.2460\/javma.230.8.1190"},{"key":"e_1_2_6_18_1","doi-asserted-by":"publisher","DOI":"10.1353\/pbm.1983.0003"},{"key":"e_1_2_6_19_1","doi-asserted-by":"publisher","DOI":"10.1016\/0022-2828(83)90303-6"},{"key":"e_1_2_6_20_1","doi-asserted-by":"publisher","DOI":"10.1210\/endo-117-4-1544"},{"key":"e_1_2_6_21_1","unstructured":"U.S. Food & Drug Administration.FDA provides update on investigation into potential connection between certain diets and cases of canine heart disease. 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