{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,26]],"date-time":"2026-08-26T07:41:51Z","timestamp":1787730111373,"version":"build-2784847793"},"reference-count":21,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2024,2,26]],"date-time":"2024-02-26T00:00:00Z","timestamp":1708905600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["J Vet Emergen Crit Care"],"published-print":{"date-parts":[[2024,3]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Objective<\/jats:title><jats:p>To describe the medical management and outcome of a dog suffering severe hydrogen peroxide toxicity.<\/jats:p><\/jats:sec><jats:sec><jats:title>Case Summary<\/jats:title><jats:p>A 3\u2010year\u2010old neutered female Bichon Frise was presented to an emergency and referral practice after ingestion of 10\u201320\u00a0mL\/kg 3% hydrogen peroxide. On presentation, the dog was obtunded, was tachypneic, and had severe gastric tympany. Abdominal radiographs revealed pneumoperitoneum, gastric pneumatosis, and hepatic venous gas. The dog was managed conservatively with supportive care and oxygen therapy. Repeat radiographs 6\u00a0hours later showed complete resolution of all gas inclusions. While hospitalized, the dog developed severe hematemesis, and abdominal ultrasound revealed severe gastric wall thickening. Subsequent endoscopy confirmed severe gastric mucosal necrosis without evidence of deeper ulceration and relatively mild petechiation of the esophagus. The dog was ultimately discharged after 5\u00a0days of hospitalization and continued to do well at home. Recheck ultrasound 5\u00a0weeks postdischarge showed normal gastric wall appearance.<\/jats:p><\/jats:sec><jats:sec><jats:title>New or Unique Information Provided<\/jats:title><jats:p>To the authors\u2019 knowledge, this is the first reported case of pneumoperitoneum secondary to hydrogen peroxide toxicity and the first description of the clinical course of severe toxicity in dogs.<\/jats:p><\/jats:sec>","DOI":"10.1111\/vec.13363","type":"journal-article","created":{"date-parts":[[2024,2,26]],"date-time":"2024-02-26T14:24:02Z","timestamp":1708957442000},"page":"179-185","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["Medical management of pneumoperitoneum, gastric pneumatosis, and hepatic venous gas secondary to 3% hydrogen peroxide toxicity in a dog"],"prefix":"10.1111","volume":"34","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-9337-7760","authenticated-orcid":false,"given":"Stefan B.","family":"Gordon","sequence":"first","affiliation":[{"name":"VCA Emergency Animal Hospital &amp; Referral Center  San Diego California USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Amy C.","family":"Nadolski","sequence":"additional","affiliation":[{"name":"VCA Emergency Animal Hospital &amp; Referral Center  San Diego California USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2024,2,26]]},"reference":[{"key":"e_1_2_7_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/B978-1-4160-2591-7.10077-3"},{"key":"e_1_2_7_3_1","doi-asserted-by":"publisher","DOI":"10.2460\/javma.241.9.1179"},{"key":"e_1_2_7_4_1","doi-asserted-by":"publisher","DOI":"10.1111\/vec.12558"},{"key":"e_1_2_7_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jemermed.2005.05.036"},{"issue":"3","key":"e_1_2_7_6_1","first-page":"323","article-title":"Hydrogen peroxide 3% exposures","volume":"34","author":"Herny MC","year":"2008","journal-title":"Clin Toxicol"},{"key":"e_1_2_7_7_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1740-8261.2009.01541.x"},{"key":"e_1_2_7_8_1","doi-asserted-by":"publisher","DOI":"10.1111\/vru.12797"},{"key":"e_1_2_7_9_1","doi-asserted-by":"publisher","DOI":"10.1111\/vec.12639"},{"key":"e_1_2_7_10_1","doi-asserted-by":"publisher","DOI":"10.2165\/00139709-200423010-00006"},{"key":"e_1_2_7_11_1","doi-asserted-by":"publisher","DOI":"10.1155\/2007\/423217"},{"key":"e_1_2_7_12_1","doi-asserted-by":"publisher","DOI":"10.1093\/bja\/38.5.339"},{"key":"e_1_2_7_13_1","doi-asserted-by":"publisher","DOI":"10.1097\/00000433-199403000-00011"},{"key":"e_1_2_7_14_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijscr.2014.10.052"},{"key":"e_1_2_7_15_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1476-4431.2011.00671.x"},{"key":"e_1_2_7_16_1","doi-asserted-by":"publisher","DOI":"10.1111\/vec.12769"},{"key":"e_1_2_7_17_1","doi-asserted-by":"publisher","DOI":"10.1186\/2036-7902-5-S1-S4"},{"key":"e_1_2_7_18_1","doi-asserted-by":"publisher","DOI":"10.5326\/0430264"},{"issue":"4","key":"e_1_2_7_19_1","first-page":"1","article-title":"Gastric pneumatosis after accidental ingestion of concentrated hydrogen peroxide: A case report","volume":"5","author":"Pham C","year":"2021","journal-title":"Clin Pract Cases Emerg Med"},{"key":"e_1_2_7_20_1","doi-asserted-by":"publisher","DOI":"10.3109\/15563659809028949"},{"key":"e_1_2_7_21_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ajem.2016.12.027"},{"key":"e_1_2_7_22_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0016-5107(04)01722-5"}],"container-title":["Journal of Veterinary Emergency and Critical Care"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/vec.13363","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,4,1]],"date-time":"2024-04-01T11:13:32Z","timestamp":1711970012000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/vec.13363"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,2,26]]},"references-count":21,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2024,3]]}},"alternative-id":["10.1111\/vec.13363"],"URL":"https:\/\/doi.org\/10.1111\/vec.13363","archive":["Portico"],"relation":{},"ISSN":["1479-3261","1476-4431"],"issn-type":[{"value":"1479-3261","type":"print"},{"value":"1476-4431","type":"electronic"}],"subject":[],"published":{"date-parts":[[2024,2,26]]},"assertion":[{"value":"2022-07-19","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2022-11-11","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2024-02-26","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}