{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,1]],"date-time":"2026-06-01T18:41:57Z","timestamp":1780339317520,"version":"3.54.1"},"reference-count":22,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2025,6,16]],"date-time":"2025-06-16T00:00:00Z","timestamp":1750032000000},"content-version":"vor","delay-in-days":46,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["J Vet Emergen Crit Care"],"published-print":{"date-parts":[[2025,5]]},"abstract":"<jats:title>ABSTRACT<\/jats:title><jats:sec><jats:title>Objective<\/jats:title><jats:p>To assess factors associated with return of spontaneous circulation (ROSC), sustained ROSC, and survival to discharge in patients undergoing CPR and to identify poor prognostic indicators to guide decisions and timing for the termination of resuscitative efforts.<\/jats:p><\/jats:sec><jats:sec><jats:title>Design<\/jats:title><jats:p>International, multi\u2010institutional veterinary CPR registry data report.<\/jats:p><\/jats:sec><jats:sec><jats:title>Setting<\/jats:title><jats:p>Sixteen veterinary private practice and university teaching hospitals in the United States, Europe, and Australia.<\/jats:p><\/jats:sec><jats:sec><jats:title>Animals<\/jats:title><jats:p>Data from 354 dogs and 138 cats with in\u2010hospital arrest undergoing CPR that were entered into the Reassessment Campaign on Veterinary Resuscitation CPR registry between February 2016 and December 2021.<\/jats:p><\/jats:sec><jats:sec><jats:title>Interventions<\/jats:title><jats:p>None.<\/jats:p><\/jats:sec><jats:sec><jats:title>Measurements and Main Results<\/jats:title><jats:p>One hundred thirty\u2010two dogs (37.3%) and 56 cats (40.6%) with in\u2010hospital cardiopulmonary arrest achieved ROSC, of which 63 dogs (17.8%) and 28 cats (20.3%) had sustained ROSC (lasting &gt;20\u00a0min), with 14 dogs (4.0%) and four cats (2.9%) surviving to hospital discharge. Maximum end\u2010tidal partial pressure of carbon dioxide (ETCO<jats:sub>2<\/jats:sub>) of \u226515\u00a0mm\u00a0Hg was associated with ROSC in cats and dogs in univariate models, ROSC in both species in a multivariate model, and sustained ROSC in dogs in univariate and multivariate models. In dogs, the odds of both sustained ROSC and survival to discharge decreased with every additional minute of CPR, and CPR delivered for \u226410\u00a0min was associated with higher odds of both ROSC and sustained ROSC in the univariate model. In both dogs and cats, the odds of achieving ROSC were higher in patients initially identified with bradycardia rather than asystole. ROSC and survival to discharge were associated with anesthetic arrests in dogs and peri\u2010anesthetic arrests in both cats and dogs.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>This study found several factors associated with ROSC that might help guide clinicians\u2019 efforts during CPR and emphasized the importance of monitoring ETCO<jats:sub>2<\/jats:sub>. Many questions remain that will need further study.<\/jats:p><\/jats:sec>","DOI":"10.1111\/vec.13473","type":"journal-article","created":{"date-parts":[[2025,6,16]],"date-time":"2025-06-16T11:40:15Z","timestamp":1750074015000},"page":"258-268","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Factors Associated With Return of Spontaneous Circulation and Survival to Hospital Discharge in Dogs and Cats Undergoing Cardiopulmonary Resuscitation Using the Reassessment Campaign on Veterinary Resuscitation (RECOVER) Database"],"prefix":"10.1111","volume":"35","author":[{"ORCID":"https:\/\/orcid.org\/0009-0003-0209-0804","authenticated-orcid":false,"given":"Selimah M.","family":"Harmon","sequence":"first","affiliation":[{"name":"University of Pennsylvania  Philadelphia Pennsylvania USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rebecka S.","family":"Hess","sequence":"additional","affiliation":[{"name":"University of Pennsylvania  Philadelphia Pennsylvania USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9276-5208","authenticated-orcid":false,"given":"Noa","family":"Berlin","sequence":"additional","affiliation":[{"name":"Beth Israel Deaconess Medical Center Harvard Medical School  Boston Massachusetts USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Deborah C.","family":"Silverstein","sequence":"additional","affiliation":[{"name":"University of Pennsylvania  Philadelphia Pennsylvania USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2025,6,16]]},"reference":[{"issue":"1","key":"e_1_2_10_2_1","first-page":"S102","article-title":"RECOVER Evidence and Knowledge Gap Analysis on Veterinary CPR. Part 7: Clinical Guidelines","volume":"22","author":"Fletcher D. J.","year":"2012","journal-title":"Journal of Veterinary Emergency and Critical Care"},{"key":"e_1_2_10_3_1","doi-asserted-by":"publisher","DOI":"10.1111\/vec.13010"},{"key":"e_1_2_10_4_1","doi-asserted-by":"publisher","DOI":"10.3389\/fvets.2019.00439"},{"key":"e_1_2_10_5_1","doi-asserted-by":"publisher","DOI":"10.1292\/jvms.17-0107"},{"key":"e_1_2_10_6_1","doi-asserted-by":"publisher","DOI":"10.1111\/vec.12250"},{"key":"e_1_2_10_7_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1939-1676.2011.00802.x"},{"key":"e_1_2_10_8_1","doi-asserted-by":"publisher","DOI":"10.1056\/nejmoa1109148"},{"key":"e_1_2_10_9_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1476-4431.2012.00753.x"},{"key":"e_1_2_10_10_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1476-4431.1992.tb00093.x"},{"key":"e_1_2_10_11_1","doi-asserted-by":"publisher","DOI":"10.1111\/vec.12755"},{"key":"e_1_2_10_12_1","doi-asserted-by":"publisher","DOI":"10.1111\/vec.12436"},{"key":"e_1_2_10_13_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jbi.2008.08.010"},{"key":"e_1_2_10_14_1","doi-asserted-by":"publisher","DOI":"10.1080\/00031305.1990.10475751"},{"key":"e_1_2_10_15_1","first-page":"385","article-title":"Prospective Evaluation of Cardiopulmonary Resuscitation Performed in Dogs and Cats According to the RECOVER Guidelines. Part 1: Prognostic Factors According to Utstein\u2010Style Reporting","volume":"6","author":"Hoehne S. N.","year":"2019","journal-title":"Frontiers in Veterinary Science"},{"key":"e_1_2_10_16_1","doi-asserted-by":"publisher","DOI":"10.2460\/javma.235.1.50"},{"key":"e_1_2_10_17_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1534-6935.2004.04006.x"},{"key":"e_1_2_10_18_1","doi-asserted-by":"publisher","DOI":"10.1542\/peds.2009-0727"},{"key":"e_1_2_10_19_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM198803103181005"},{"key":"e_1_2_10_20_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(12)60862-9"},{"key":"e_1_2_10_21_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ihj.2019.09.002"},{"key":"e_1_2_10_22_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.resuscitation.2018.08.017"},{"issue":"2","key":"e_1_2_10_23_1","first-page":"133","article-title":"Outcome From Cardiopulmonary Resuscitation in Cats: Laboratory and Clinical Experience","volume":"23","author":"Gilroy B. A.","year":"1987","journal-title":"Journal of the American Animal Hospital Association"}],"container-title":["Journal of Veterinary Emergency and Critical Care"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/vec.13473","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,10,17]],"date-time":"2025-10-17T07:03:25Z","timestamp":1760684605000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/vec.13473"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,5]]},"references-count":22,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2025,5]]}},"alternative-id":["10.1111\/vec.13473"],"URL":"https:\/\/doi.org\/10.1111\/vec.13473","archive":["Portico"],"relation":{},"ISSN":["1479-3261","1476-4431"],"issn-type":[{"value":"1479-3261","type":"print"},{"value":"1476-4431","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,5]]},"assertion":[{"value":"2023-06-02","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2025-04-16","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2025-06-16","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}