{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,26]],"date-time":"2026-08-26T23:15:20Z","timestamp":1787786120305,"version":"build-2784847793"},"reference-count":31,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2025,8,30]],"date-time":"2025-08-30T00:00:00Z","timestamp":1756512000000},"content-version":"vor","delay-in-days":60,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["J Vet Emergen Crit Care"],"published-print":{"date-parts":[[2025,7]]},"abstract":"<jats:title>ABSTRACT<\/jats:title><jats:sec><jats:title>Objective<\/jats:title><jats:p>To describe the management of a unique case of hypermagnesemia in a cat.<\/jats:p><\/jats:sec><jats:sec><jats:title>Case Summary<\/jats:title><jats:p>An 8\u2010year\u2010old spayed female domestic shorthair cat was presented for acute\u2010onset stupor, hypothermia, and bradycardia. Overtly elevated ionized (&gt;1.5\u00a0mmol\/L [&gt;3.6\u00a0mg\/dL]; reference interval: 0.4\u20130.8\u00a0mmol\/L [0.9\u20131.9\u00a0mg\/dL]) and total magnesium (3.0\u00a0mmol\/L [7.3\u00a0mg\/dL]; reference interval: 0.74\u20131.0\u00a0mmol\/L [1.8\u20132.5\u00a0mg\/dL]) concentrations were identified. A thorough history uncovered the long\u2010term at\u2010home administration of an anxiolytic supplement containing magnesium stearate as an inactive ingredient. No other sources of nondietary magnesium were identified. A diagnosis of magnesium toxicosis was reached. Secondarily, an acute kidney injury developed. After 10\u00a0days of hospitalization, the cat was successfully discharged with normalized kidney and electrolyte values.<\/jats:p><\/jats:sec><jats:sec><jats:title>New or Unique Information Provided<\/jats:title><jats:p>Few case reports regarding magnesium toxicosis and its management exist in the veterinary literature. A rare case of hypermagnesemia is presented in this report, highlighting the importance of a complete laboratory workup that includes an evaluation of magnesium levels in previously healthy animals that present with otherwise unexplained clinical signs.<\/jats:p><\/jats:sec>","DOI":"10.1111\/vec.70021","type":"journal-article","created":{"date-parts":[[2025,8,30]],"date-time":"2025-08-30T15:43:58Z","timestamp":1756568638000},"page":"442-448","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Hypermagnesemia in a Cat Secondary to Suspected Intoxication"],"prefix":"10.1111","volume":"35","author":[{"ORCID":"https:\/\/orcid.org\/0009-0003-1448-7710","authenticated-orcid":false,"given":"Jackson A.","family":"Griffith","sequence":"first","affiliation":[{"name":"Michigan State University Veterinary Teaching Hospital  East Lansing Michigan USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Melissa R.","family":"Santonocito","sequence":"additional","affiliation":[{"name":"Michigan State University Veterinary Teaching Hospital  East Lansing Michigan USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0297-3020","authenticated-orcid":false,"given":"Katie D.","family":"Mauro","sequence":"additional","affiliation":[{"name":"Michigan State University Veterinary Teaching Hospital  East Lansing Michigan USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2025,8,30]]},"reference":[{"key":"e_1_2_8_2_1","doi-asserted-by":"publisher","DOI":"10.1111\/vec.12253"},{"key":"e_1_2_8_3_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM196803282781306"},{"key":"e_1_2_8_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/0736-4679(95)02115-9"},{"key":"e_1_2_8_5_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1939-1676.2002.tb02360.x"},{"key":"e_1_2_8_6_1","volume-title":"StatPearls","author":"Ajib F. 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