{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,4]],"date-time":"2025-10-04T00:22:31Z","timestamp":1759537351386,"version":"build-2065373602"},"reference-count":21,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2025,8,30]],"date-time":"2025-08-30T00:00:00Z","timestamp":1756512000000},"content-version":"vor","delay-in-days":60,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["J Vet Emergen Crit Care"],"published-print":{"date-parts":[[2025,7]]},"abstract":"<jats:title>ABSTRACT<\/jats:title><jats:sec><jats:title>Objective<\/jats:title><jats:p>To describe hypoglycemia secondary to zinc toxicosis in a dog.<\/jats:p><\/jats:sec><jats:sec><jats:title>Case Summary<\/jats:title><jats:p>A 3\u2010year\u2010old spayed female Pug weighing 9.0\u00a0kg presented with lethargy and labored breathing. Diagnostic tests revealed hypoglycemia, regenerative anemia, azotemia, increased liver values, and metallic objects in the stomach. The dog was treated with IV dextrose but remained refractory to therapy for the first 5\u00a0h. A serum zinc concentration was 32.28\u00a0\u00b5g\/mL (reference interval, 0.8\u20131.8\u00a0\u00b5g\/mL). The dog was treated supportively, and the blood glucose concentration responded within hours of endoscopic removal of the metallic foreign bodies.<\/jats:p><\/jats:sec><jats:sec><jats:title>New or Unique Information Provided<\/jats:title><jats:p>This case demonstrates refractory hypoglycemia associated with zinc toxicosis, which has not been previously reported in the literature.<\/jats:p><\/jats:sec>","DOI":"10.1111\/vec.70024","type":"journal-article","created":{"date-parts":[[2025,8,30]],"date-time":"2025-08-30T15:36:45Z","timestamp":1756568205000},"page":"449-454","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Refractory Hypoglycemia in a Dog With Severe Zinc Intoxication"],"prefix":"10.1111","volume":"35","author":[{"ORCID":"https:\/\/orcid.org\/0009-0009-6671-5432","authenticated-orcid":false,"given":"John","family":"Vietti","sequence":"first","affiliation":[{"name":"Department of Veterinary Emergency and Critical Care Veterinary Specialty Center  Bannockburn Illinois USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jennifer","family":"Herring","sequence":"additional","affiliation":[{"name":"Department of Veterinary Emergency and Critical Care Veterinary Specialty Center  Bannockburn Illinois USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shaunita","family":"Sharpe","sequence":"additional","affiliation":[{"name":"Department of Veterinary Emergency and Critical Care Veterinary Specialty Center  Bannockburn Illinois USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Barb","family":"Gertz","sequence":"additional","affiliation":[{"name":"Department of Veterinary Emergency and Critical Care Veterinary Specialty Center  Bannockburn Illinois USA"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2025,8,30]]},"reference":[{"key":"e_1_2_8_2_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1476\u20104431.2009.00418.x"},{"key":"e_1_2_8_3_1","doi-asserted-by":"publisher","DOI":"10.1186\/s40199\u2010015\u20100127\u20104"},{"key":"e_1_2_8_4_1","doi-asserted-by":"publisher","DOI":"10.1006\/gcen.2001.7612"},{"key":"e_1_2_8_5_1","doi-asserted-by":"publisher","DOI":"10.2337\/db09-1098"},{"key":"e_1_2_8_6_1","doi-asserted-by":"publisher","DOI":"10.7759\/cureus.38828"},{"key":"e_1_2_8_7_1","doi-asserted-by":"publisher","DOI":"10.1111\/vec.13330"},{"volume-title":"Small Animal Toxicology","year":"2012","author":"Patricia A.","key":"e_1_2_8_8_1"},{"key":"e_1_2_8_9_1","doi-asserted-by":"publisher","DOI":"10.2460\/javma.230.8.1174"},{"key":"e_1_2_8_10_1","doi-asserted-by":"publisher","DOI":"10.1111\/vec.12414"},{"key":"e_1_2_8_11_1","first-page":"96","article-title":"Zinc Toxicosis From Penny Ingestion in Dogs","volume":"97","author":"Richardson J A.","year":"2002","journal-title":"Veterinary Medicine"},{"key":"e_1_2_8_12_1","doi-asserted-by":"publisher","DOI":"10.3390\/nu11051027"},{"key":"e_1_2_8_13_1","doi-asserted-by":"publisher","DOI":"10.1002\/9781118785669"},{"key":"e_1_2_8_14_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jinorgbio.2006.12.015"},{"key":"e_1_2_8_15_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00775-004-0590-8"},{"key":"e_1_2_8_16_1","doi-asserted-by":"publisher","DOI":"10.1246\/bcsj.78.451"},{"key":"e_1_2_8_17_1","doi-asserted-by":"publisher","DOI":"10.1002\/mabi.200800190"},{"key":"e_1_2_8_18_1","doi-asserted-by":"publisher","DOI":"10.1248\/cpb.50.337"},{"key":"e_1_2_8_19_1","doi-asserted-by":"publisher","DOI":"10.3177\/jnsv.29.655"},{"key":"e_1_2_8_20_1","doi-asserted-by":"publisher","DOI":"10.2337\/diabetes.54.6.1808"},{"key":"e_1_2_8_21_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00125\u2010010\u20101793\u2010x"},{"issue":"5","key":"e_1_2_8_22_1","first-page":"272","article-title":"Diagnosis and Treatment of Zinc Poisoning in a Dog","volume":"46","author":"Hammond G. 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