{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,15]],"date-time":"2026-10-15T08:46:25Z","timestamp":1792053985144,"version":"4.4.0"},"reference-count":50,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2026,4,3]],"date-time":"2026-04-03T00:00:00Z","timestamp":1775174400000},"content-version":"vor","delay-in-days":33,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"},{"start":{"date-parts":[[2026,3,1]],"date-time":"2026-03-01T00:00:00Z","timestamp":1772323200000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["J Vet Emergen Crit Care"],"published-print":{"date-parts":[[2026,3]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Objective<\/jats:title>\n                    <jats:p>To describe a population of dogs and cats with cancer admitted to the ICU and identify risk factors affecting survival.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Design<\/jats:title>\n                    <jats:p>Prospective, observational cohort study between December 2022 and September 2023.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Setting<\/jats:title>\n                    <jats:p>Veterinary referral teaching hospital.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Animals<\/jats:title>\n                    <jats:p>Thirty\u2010eight cats and 114 dogs.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Interventions<\/jats:title>\n                    <jats:p>All ICU admissions were recorded. For patients with a confirmed or presumed cancer diagnosis, reason for ICU admission, clinicopathologic data, diagnostic imaging results, treatments, survival to discharge and at 90\u00a0days postdischarge, and date of death, if applicable, were recorded.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Measurements and Main Results<\/jats:title>\n                    <jats:p>\n                      The prevalence of ICU patients with cancer was 13.6% (165\/1214 [95% confidence interval {CI}: 11.7\u201315.7]). A definitive diagnosis was obtained in 106 patients (73.7% [28\/38] cats, 68.4% [78\/114] dogs). Hematologic neoplasia was the most frequent cancer in cats (64.3% [18\/28]), while carcinoma was the most frequent in dogs (37.2% [29\/78]). The most frequent reasons for ICU admission were respiratory distress (31.6% [12\/38] cats, 20.2% [24\/114] dogs) and cardiovascular instability (21.1% [8\/38] cats, 20.2% [23\/114] dogs). Survival to discharge was 56.6% (44.7% [17\/38] cats, 60.5% [69\/114] dogs) and at 90\u00a0days was 30.6% (21.1% [8\/38] cats, 33.9% [37\/109] dogs). In the multivariable Cox regression model, oncologic ICU admission was associated with increased hazard of death compared with nononcologic admission (hazard ratio [HR]: 6.06, 95% CI: 2.39\u201315.36;\n                      <jats:italic>p<\/jats:italic>\n                      \u00a0&lt;\u00a00.001); surgical treatment was associated with reduced hazard compared with medical treatment (HR: 0.21, 95% CI: 0.11\u20130.38;\n                      <jats:italic>p<\/jats:italic>\n                      \u00a0&lt;\u00a00.001); chemotherapy was associated with reduced hazard compared with no chemotherapy (HR: 0.40, 95% CI: 0.22\u20130.73;\n                      <jats:italic>p<\/jats:italic>\n                      \u00a0=\u00a00.003); and normal albumin concentration in dogs was associated with reduced hazard compared with hypoalbuminemia (HR: 0.44, 95% CI: 0.26\u20130.72;\n                      <jats:italic>p<\/jats:italic>\n                      \u00a0=\u00a00.004).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>Cancer was common in this ICU population (prevalence 13.6%). Mortality was high (69.4% 3\u00a0months postdischarge), with 88% of deaths resulting from euthanasia.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/vec.70105","type":"journal-article","created":{"date-parts":[[2026,4,3]],"date-time":"2026-04-03T07:29:27Z","timestamp":1775201367000},"page":"197-210","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Prevalence and Risk Factors for Survival in Dogs and Cats With Cancer Admitted to the ICU"],"prefix":"10.1111","volume":"36","author":[{"given":"Clara","family":"Mattavelli","sequence":"first","affiliation":[{"name":"Department of Clinical Science and Services, The Royal Veterinary College The University of London  Hatfield UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alexandra","family":"Guill\u00e9n","sequence":"additional","affiliation":[{"name":"Department of Clinical Science and Services, The Royal Veterinary College The University 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