{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,10]],"date-time":"2026-07-10T03:18:28Z","timestamp":1783653508200,"version":"3.55.0"},"reference-count":25,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2026,5,14]],"date-time":"2026-05-14T00:00:00Z","timestamp":1778716800000},"content-version":"vor","delay-in-days":13,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"},{"start":{"date-parts":[[2026,5,1]],"date-time":"2026-05-01T00:00:00Z","timestamp":1777593600000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["J Vet Emergen Crit Care"],"published-print":{"date-parts":[[2026,5]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Objective<\/jats:title>\n                    <jats:p>To describe the medical management with mechanical ventilation of a dog with severe barium sulfate aspiration and concurrent canine acute eosinophilic dermatitis with edema.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Case summary<\/jats:title>\n                    <jats:p>\n                      A 26\u2010month\u2010old castrated male Golden Retriever was presented in respiratory distress after the accidental administration of approximately 300\u00a0mL of barium sulfate in the lower airways via an improperly placed orogastric tube. Thoracic radiographs revealed marked bilateral aspiration of contrast material. Despite oxygen supplementation via nasal cannulas, there was concern for respiratory muscle fatigue, and mechanical ventilation was provided for approximately 4\u00a0days. At the time mechanical ventilation was initiated, PaO\n                      <jats:sub>2<\/jats:sub>\n                      was 135.9\u00a0mm\u00a0Hg, FiO\n                      <jats:sub>2<\/jats:sub>\n                      was 85%, and the PaO\n                      <jats:sub>2<\/jats:sub>\n                      :FiO\n                      <jats:sub>2<\/jats:sub>\n                      ratio was 159. On Day 3 after admission, focal erythematous macules and wheals were appreciated on both the lateral thorax and abdomen, and in the perianal region. Histopathology of these lesions was consistent with canine acute eosinophilic dermatitis with edema. The dog was weaned from mechanical ventilation on Day 4 when PaO\n                      <jats:sub>2<\/jats:sub>\n                      was 86.2\u00a0mm\u00a0Hg, FiO\n                      <jats:sub>2<\/jats:sub>\n                      was 45%, and PaO\n                      <jats:sub>2<\/jats:sub>\n                      :FiO\n                      <jats:sub>2<\/jats:sub>\n                      was 216. At discharge (Day 13), the\u00a0A\u2013a gradient was 25\u00a0mm\u00a0Hg on room air. Four weeks after discharge, the patient was asymptomatic, had an A\u2013a gradient of 6\u00a0mm\u00a0Hg on room air, and had resolved dermatologic lesions.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>New or Unique Information<\/jats:title>\n                    <jats:p>This is the first case report of the successful medical management of severe barium aspiration in a dog that required mechanical ventilation, with an excellent outcome.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/vec.70111","type":"journal-article","created":{"date-parts":[[2026,5,14]],"date-time":"2026-05-14T11:29:36Z","timestamp":1778758176000},"page":"417-423","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Medical Management With Mechanical Ventilation of a Dog With Severe Barium Sulfate Aspiration"],"prefix":"10.1111","volume":"36","author":[{"given":"Mathieu V.","family":"Paulin","sequence":"first","affiliation":[{"name":"Department of Small Animal Clinical Sciences, Western College of Veterinary Medicine University of Saskatchewan  Saskatoon Saskatchewan Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Allison A.","family":"Foster","sequence":"additional","affiliation":[{"name":"Department of Small Animal Clinical Sciences, Western College of Veterinary Medicine University of Saskatchewan  Saskatoon Saskatchewan Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jennifer M.","family":"Loewen","sequence":"additional","affiliation":[{"name":"Department of Small Animal Clinical Sciences, Western College of Veterinary Medicine University of Saskatchewan  Saskatoon Saskatchewan Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2026,5,14]]},"reference":[{"key":"e_1_2_9_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0195-5616(83)50062-4"},{"key":"e_1_2_9_3_1","doi-asserted-by":"publisher","DOI":"10.4103\/2452-2473.276383"},{"key":"e_1_2_9_4_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1476-4431.2008.00368.x"},{"key":"e_1_2_9_5_1","doi-asserted-by":"publisher","DOI":"10.1136\/bcr.02.2012.5891"},{"key":"e_1_2_9_6_1","first-page":"500","volume-title":"Textbook of Veterinary Diagnostic Radiology","author":"Gaschen L.","year":"2013"},{"key":"e_1_2_9_7_1","doi-asserted-by":"publisher","DOI":"10.1007\/BF01889065"},{"key":"e_1_2_9_8_1","doi-asserted-by":"publisher","DOI":"10.1148\/radiology.161.1.3763856"},{"key":"e_1_2_9_9_1","doi-asserted-by":"publisher","DOI":"10.1111\/vec.12820"},{"key":"e_1_2_9_10_1","doi-asserted-by":"publisher","DOI":"10.2460\/javma.237.5.547"},{"key":"e_1_2_9_11_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.cvsm.2018.08.005"},{"key":"e_1_2_9_12_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1939-1676.2012.00927.x"},{"key":"e_1_2_9_13_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.mcna.2010.04.006"},{"key":"e_1_2_9_14_1","doi-asserted-by":"publisher","DOI":"10.1111\/vec.12713"},{"key":"e_1_2_9_15_1","doi-asserted-by":"publisher","DOI":"10.1016\/B978-1-4557-0306-7.00014-3"},{"key":"e_1_2_9_16_1","first-page":"595","article-title":"Further Experience With Barium Sulfate as a Bronchographic Contrast Medium","volume":"92","author":"Nelson S. 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