{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,10]],"date-time":"2026-07-10T03:16:23Z","timestamp":1783653383639,"version":"3.55.0"},"reference-count":24,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2026,5,26]],"date-time":"2026-05-26T00:00:00Z","timestamp":1779753600000},"content-version":"vor","delay-in-days":25,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"},{"start":{"date-parts":[[2026,5,1]],"date-time":"2026-05-01T00:00:00Z","timestamp":1777593600000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["J Vet Emergen Crit Care"],"published-print":{"date-parts":[[2026,5]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Objective<\/jats:title>\n                    <jats:p>To evaluate the safety of IV lecithin\u2010solubilizing agent\u2010based vitamin K1 (VK\u2010LSE) administration and compare the outcomes in dogs and cats with anticoagulant rodenticide (AR) poisoning that received IV VK\u2010LSE with or without exogenous coagulation factors (CF).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Design<\/jats:title>\n                    <jats:p>Retrospective study (January 2010 to January 2022).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Setting<\/jats:title>\n                    <jats:p>University teaching hospital.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Animals<\/jats:title>\n                    <jats:p>Forty\u2010seven dogs and 11 cats.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Interventions<\/jats:title>\n                    <jats:p>None.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Measurements and Main Results<\/jats:title>\n                    <jats:p>\n                      Medical records from dogs and cats diagnosed with AR poisoning were reviewed. Fifty\u2010eight patients received VK\u2010LSE (5\u00a0mg\/kg, IV). Two groups, animals that received VK\u2010LSE without CF (VK group) and animals that received VK\u2010LSE and CF (VK\u2010CF group), were identified. No adverse effects were recorded after IV VK\u2010LSE administration. Twenty\u2010nine of 58 patients received exogenous CF. No patient received fresh frozen plasma. All patients had coagulation times within reference intervals by 24\u00a0h following admission. There was no difference in survival to discharge for dogs (96% VK vs. 85% VK\u2010CF,\n                      <jats:italic>p<\/jats:italic>\n                      \u00a0=\u00a00.22) or for cats (100%, both groups) between groups.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>IV administration of VK\u2010LSE appears to be safe, with no reported adverse effects. In AR\u2010poisoned dogs and cats, IV VK\u2010LSE administration without exogenous CF appears to rapidly normalize coagulation times, with high survival rates and short hospitalization lengths.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/vec.70120","type":"journal-article","created":{"date-parts":[[2026,5,26]],"date-time":"2026-05-26T14:55:32Z","timestamp":1779807332000},"page":"365-371","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Intravenous Administration of Vitamin K1 in Dogs and Cats Presented for Anticoagulant Rodenticide Poisoning: A Retrospective Study of 58 Cases"],"prefix":"10.1111","volume":"36","author":[{"given":"Camille","family":"Dartencet","sequence":"first","affiliation":[{"name":"Universit\u00e9 De Lyon, VetAgro Sup, Campus v\u00e9t\u00e9rinaire de Lyon, Intensive Care Unit (SIAMU), APCSe  Marcy\u2010l'Etoile France"},{"name":"Universit\u00e9 De Lyon, VetAgro Sup, Campus v\u00e9t\u00e9rinaire de Lyon, APCSe  Marcy\u2010l'\u00c9toile France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"C\u00e9line","family":"Pouzot\u2010Nevoret","sequence":"additional","affiliation":[{"name":"Universit\u00e9 De Lyon, VetAgro Sup, Campus v\u00e9t\u00e9rinaire de Lyon, Intensive Care Unit (SIAMU), APCSe  Marcy\u2010l'Etoile France"},{"name":"Universit\u00e9 De Lyon, VetAgro Sup, Campus v\u00e9t\u00e9rinaire de Lyon, APCSe  Marcy\u2010l'\u00c9toile France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marine","family":"Poupon","sequence":"additional","affiliation":[{"name":"Universit\u00e9 De Lyon, VetAgro Sup, Campus v\u00e9t\u00e9rinaire de Lyon, Intensive Care Unit (SIAMU), APCSe  Marcy\u2010l'Etoile France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mark W.","family":"Kim","sequence":"additional","affiliation":[{"name":"Universit\u00e9 De Lyon, VetAgro Sup, Campus v\u00e9t\u00e9rinaire de Lyon, Intensive Care Unit (SIAMU), APCSe  Marcy\u2010l'Etoile France"},{"name":"Universit\u00e9 De Lyon, VetAgro Sup, Campus v\u00e9t\u00e9rinaire de Lyon, APCSe  Marcy\u2010l'\u00c9toile France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bernard","family":"Allaouchiche","sequence":"additional","affiliation":[{"name":"Universit\u00e9 De Lyon, VetAgro Sup, Campus v\u00e9t\u00e9rinaire de Lyon, APCSe  Marcy\u2010l'\u00c9toile France"},{"name":"Hospices Civils de Lyon, Centre Hospitalier Lyon\u2010Sud, Service de R\u00e9animation  Pierre\u2010B\u00e9nite France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alexandra","family":"Nectoux","sequence":"additional","affiliation":[{"name":"Universit\u00e9 De Lyon, VetAgro Sup, Campus v\u00e9t\u00e9rinaire de Lyon, Intensive Care Unit (SIAMU), APCSe  Marcy\u2010l'Etoile France"},{"name":"Universit\u00e9 De Lyon, VetAgro Sup, Campus v\u00e9t\u00e9rinaire de Lyon, APCSe  Marcy\u2010l'\u00c9toile France"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2026,5,26]]},"reference":[{"key":"e_1_2_9_2_1","doi-asserted-by":"publisher","DOI":"10.1111\/vec.12748"},{"key":"e_1_2_9_3_1","doi-asserted-by":"publisher","DOI":"10.2460\/javma.1992.200.08.1077"},{"key":"e_1_2_9_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.tvjl.2009.03.034"},{"key":"e_1_2_9_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/0092\u20108674(88)90567\u20103"},{"key":"e_1_2_9_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0021-9258(18)92033-8"},{"key":"e_1_2_9_7_1","doi-asserted-by":"publisher","DOI":"10.1016\/0003\u20109861(69)90525\u20106"},{"key":"e_1_2_9_8_1","doi-asserted-by":"publisher","DOI":"10.3109\/10409238009105469"},{"key":"e_1_2_9_9_1","doi-asserted-by":"publisher","DOI":"10.1016\/0003\u20109861(72)90014\u20108"},{"key":"e_1_2_9_10_1","doi-asserted-by":"publisher","DOI":"10.1111\/avj.12931"},{"key":"e_1_2_9_11_1","first-page":"583","volume-title":"Veterinary Toxicology","author":"Murphy M. 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