{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,10]],"date-time":"2026-07-10T03:17:07Z","timestamp":1783653427851,"version":"3.55.0"},"reference-count":26,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2026,5,27]],"date-time":"2026-05-27T00:00:00Z","timestamp":1779840000000},"content-version":"vor","delay-in-days":26,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"},{"start":{"date-parts":[[2026,5,1]],"date-time":"2026-05-01T00:00:00Z","timestamp":1777593600000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["J Vet Emergen Crit Care"],"published-print":{"date-parts":[[2026,5]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Objective<\/jats:title>\n                    <jats:p>To describe the clinical course, outcome, necropsy findings, possible mechanisms of toxicosis, and treatment implications for three cats with acute kidney injury and associated systemic signs secondary to accidental oclacitinib ingestion.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Series Summary<\/jats:title>\n                    <jats:p>Three cats ingested large (&gt;100\u00a0mg\/kg) overdoses of oclacitinib, leading to severe acute kidney injury and associated systemic illness. Two of the three cats subsequently died or were euthanized, while the third cat made a full recovery after receiving intensive supportive care.\u00a0Necropsies were performed on the two deceased cats, with no definitive mechanism for toxicosis identified.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>New or Unique Information Provided<\/jats:title>\n                    <jats:p>This is the first case series of accidental oclacitinib toxicosis in cats. Recognition of this emerging concern can aid clinicians in minimizing exposure risks where possible, as well as providing prompt treatment in overdose situations.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/vec.70123","type":"journal-article","created":{"date-parts":[[2026,5,28]],"date-time":"2026-05-28T06:59:41Z","timestamp":1779951581000},"page":"378-383","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Severe Toxicosis Secondary to Accidental Oclacitinib Ingestion in Three Cats"],"prefix":"10.1111","volume":"36","author":[{"given":"Jessica Kielb","family":"Basile","sequence":"first","affiliation":[{"name":"BluePearl Veterinary Partners  Levittown Pennsylvania USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sara C.","family":"Lister","sequence":"additional","affiliation":[{"name":"ASPCA Poison Control  Champaign Illinois USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2026,5,27]]},"reference":[{"key":"e_1_2_10_2_1","volume-title":"Apoquel (Oclacitinib)","author":"Zoetis Inc","year":"2013"},{"key":"e_1_2_10_3_1","doi-asserted-by":"publisher","DOI":"10.1186\/s12917\u2010019\u20101893\u2010x"},{"key":"e_1_2_10_4_1","doi-asserted-by":"publisher","DOI":"10.1111\/jvp.13503"},{"key":"e_1_2_10_5_1","doi-asserted-by":"publisher","DOI":"10.1080\/1744666X.2022.2014323"},{"key":"e_1_2_10_6_1","unstructured":"United States Food and Drug Administration \u201cJanus Kinase (JAK) Inhibitors: Drug Safety Communication\u2014FDA Requires Warnings About Increased Risk of Serious Heart\u2010Related Events Cancer Blood Clots and Death \u201d published September 1 2021 https:\/\/www.fda.gov\/safety\/medical\u2010product\u2010safety\u2010information\/janus\u2010kinase\u2010jak\u2010inhibitors\u2010drug\u2010safety\u2010communication\u2010fda\u2010requires\u2010warnings\u2010about\u2010increased\u2010risk."},{"key":"e_1_2_10_7_1","doi-asserted-by":"publisher","DOI":"10.2460\/javma.22.12.0570"},{"key":"e_1_2_10_8_1","doi-asserted-by":"crossref","unstructured":"C.Ortalda C.Noli S.Colombo andS.Borio \u201cOclacitinib in Feline Nonflea\u2010 Nonfood\u2010Induced Hypersensitivity Dermatitis: Results of a Small Prospective Pilot Study of Client\u2010Owned Cats \u201dVeterinary Dermatology26 no.4(2015): 235\u2013e52 https:\/\/doi.org\/10.1111\/vde.12218.","DOI":"10.1111\/vde.12218"},{"key":"e_1_2_10_9_1","doi-asserted-by":"publisher","DOI":"10.1111\/vde.12949"},{"key":"e_1_2_10_10_1","doi-asserted-by":"publisher","DOI":"10.1177\/1098612x211048458"},{"key":"e_1_2_10_11_1","unstructured":"C. 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