{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,18]],"date-time":"2026-08-18T01:24:15Z","timestamp":1787016255359,"version":"build-2736575974"},"reference-count":24,"publisher":"Wiley","issue":"s1","license":[{"start":{"date-parts":[[2013,1,3]],"date-time":"2013-01-03T00:00:00Z","timestamp":1357171200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Veterinary Ophthalmology"],"published-print":{"date-parts":[[2013,7]]},"abstract":"Abstract<\/jats:title>\n \n A 16\u2010year\u2010old spayed female cat was evaluated for lagophthalmos and chronic exposure keratitis in both eyes. Ophthalmic examination revealed upper and lower eyelid entropion of the left eye (\n OS<\/jats:styled-content>\n ) and markedly decreased retropulsion, restricted eye movement, marked episcleral congestion, and severe keratitis of both eyes (\n OU<\/jats:styled-content>\n ). Magnetic resonance imaging of both orbits revealed extensive, irregular, contrast\u2010enhancing tissue without evidence of osteolysis considered compatible with diffuse inflammatory tissue. Feline herpesvirus\n DNA<\/jats:styled-content>\n was not detected in conjunctival samples. Partial temporary tarsorrhaphies were placed\n OU<\/jats:styled-content>\n , and the cat was treated with topically administered erythromycin ointment\n OU<\/jats:styled-content>\n , orally administered famciclovir and prednisolone, and sublingually administered buprenorphine. Little improvement was noted after 2\u00a0weeks. Six weeks after initial presentation, a left exenteration was performed and histopathology was consistent with idiopathic sclerosing orbital pseudotumor (\n ISOP<\/jats:styled-content>\n ). Ten weeks after initial presentation, the patient represented for weight loss and jaw pain. Computed tomography demonstrated disease progression in the right orbit and the patient was euthanized. Histopathology of the decalcified skull revealed an aggressive and highly infiltrative mass involving the right orbit with extension to the maxilla, hard palate, nasal cavity and gingiva most consistent with feline restrictive orbital myofibroblastic sarcoma (\n FROMS<\/jats:styled-content>\n ). Clinical data from this patient support the reclassification of\n ISOP<\/jats:styled-content>\n as\n FROMS<\/jats:styled-content>\n .\n MRI<\/jats:styled-content>\n and\n CT<\/jats:styled-content>\n may provide supportive evidence for\n FROMS<\/jats:styled-content>\n , but histopathology is necessary for definitive diagnosis. Aggressive and early surgical treatment, including bilateral exenteration, with adjunctive radiotherapy and\/or chemotherapy should be considered for patients with\n FROMS<\/jats:styled-content>\n .\n <\/jats:p>","DOI":"10.1111\/vop.12016","type":"journal-article","created":{"date-parts":[[2013,1,3]],"date-time":"2013-01-03T04:05:27Z","timestamp":1357185927000},"page":"123-129","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":24,"title":["Restrictive orbital myofibroblastic sarcoma in a cat \u2013 Cross\u2010sectional imaging (\n MRI<\/scp>\n &\n CT<\/scp>\n ) appearance, treatment, and outcome"],"prefix":"10.1111","volume":"16","author":[{"given":"Sara M.","family":"Thomasy","sequence":"first","affiliation":[{"name":"Veterinary Medical Teaching Hospital School of Veterinary Medicine University of California\u2010Davis Davis CA 95616 USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Derek 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