{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,2]],"date-time":"2026-10-02T02:22:32Z","timestamp":1790907752893,"version":"4.1.0"},"reference-count":29,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2013,6,14]],"date-time":"2013-06-14T00:00:00Z","timestamp":1371168000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Veterinary Ophthalmology"],"published-print":{"date-parts":[[2014,9]]},"abstract":"Abstract<\/jats:title>\n \n Objective<\/jats:title>\n \n To review the signalment, clinical characteristics, treatment, and outcome of equine\n EK<\/jats:styled-content>\n cases in the\n M<\/jats:styled-content>\n id\u2010\n A<\/jats:styled-content>\n tlantic\n U<\/jats:styled-content>\n nited\n S<\/jats:styled-content>\n tates; to evaluate the effects of topical or systemic corticosteroid treatment, oral cetirizine treatment and secondary corneal infection on disease duration; and to evaluate the association between corticosteroid and cetirizine treatment and likelihood of recurrence.\n <\/jats:p>\n <\/jats:sec>\n \n Animals<\/jats:title>\n \n Twenty\u2010seven horses (47 eyes) diagnosed with\n EK<\/jats:styled-content>\n from 2008 to 2012.\n <\/jats:p>\n <\/jats:sec>\n \n Procedure<\/jats:title>\n Retrospective medical record review followed by phone interview to obtain recurrence data.<\/jats:p>\n <\/jats:sec>\n \n Results<\/jats:title>\n \n Average age of affected horses was 8.2\u00a0years,\n SD<\/jats:styled-content>\n 5.8\u00a0years. Eleven of 27 horses (41%) were diagnosed with\n EK<\/jats:styled-content>\n in July. Twelve horses (44%) had been affected in previous years. Time to resolution averaged 3.7\u00a0months,\n SD<\/jats:styled-content>\n 2.3\u00a0months. Ten horses (18 eyes) were treated with systemic dexamethasone, with a significantly shorter time to resolution,\n P<\/jats:italic>\n \u00a0=\u00a00.03, averaging 2.23\u00a0months,\n SD<\/jats:styled-content>\n 1.13\u00a0months, relative to horses not so treated, averaging 4.20\u00a0months,\n SD<\/jats:styled-content>\n 1.47\u00a0months. Secondary infection led to a significant increase in time to resolution,\n P<\/jats:italic>\n \u00a0=\u00a00.03, average 4.1\u00a0months,\n SD<\/jats:styled-content>\n 1.7\u00a0months, relative to horses without secondary infection, average 3.0\u00a0months,\n SD<\/jats:styled-content>\n 1.5\u00a0months. All eyes were visual at resolution. Horses treated with cetirizine were less likely to have recurrence during the follow\u2010up period (1\/13, or 8%) relative to horses not so treated (8\/14, or 57%).\n <\/jats:p>\n <\/jats:sec>\n \n Conclusions<\/jats:title>\n \n Eosinophilic keratitis has a seasonal occurrence in summer in the\n M<\/jats:styled-content>\n id\u2010\n A<\/jats:styled-content>\n tlantic\n U<\/jats:styled-content>\n nited\n S<\/jats:styled-content>\n tates. Systemic but not topical corticosteroid treatment may decrease therapy duration. Treatment with cetirizine may be associated with a decreased risk of recurrence.\n <\/jats:p>\n <\/jats:sec>","DOI":"10.1111\/vop.12076","type":"journal-article","created":{"date-parts":[[2013,6,14]],"date-time":"2013-06-14T05:25:41Z","timestamp":1371187541000},"page":"311-320","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":31,"title":["Eosinophilic keratitis in 46 eyes of 27 horses in the\n M<\/scp>\n id\u2010\n A<\/scp>\n tlantic\n U<\/scp>\n nited\n S<\/scp>\n tates (2008\u20132012)"],"prefix":"10.1111","volume":"17","author":[{"given":"Mary","family":"Lassaline\u2010Utter","sequence":"first","affiliation":[{"name":"New Bolton Center University of Pennsylvania School of Veterinary Medicine 382 West Street Road Kennett Square PA 19348 USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chelsey","family":"Miller","sequence":"additional","affiliation":[{"name":"New Bolton Center University of Pennsylvania School of Veterinary Medicine 382 West Street Road Kennett Square PA 19348 USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kathryn L.","family":"Wotman","sequence":"additional","affiliation":[{"name":"New Bolton Center University of Pennsylvania School of Veterinary Medicine 382 West Street Road Kennett Square PA 19348 USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2013,6,14]]},"reference":[{"key":"e_1_2_5_2_1","doi-asserted-by":"crossref","first-page":"1308","DOI":"10.2460\/javma.1994.205.09.1308","article-title":"Eosinophilic keratoconjunctivitis in a horse","volume":"205","author":"Ramsey DT","year":"1994","journal-title":"Journal of the American Veterinary Medical Association"},{"key":"e_1_2_5_3_1","doi-asserted-by":"crossref","first-page":"1283","DOI":"10.2460\/javma.1996.209.07.1283","article-title":"Eosinophilic keratoconjunctivitis in seven horses","volume":"209","author":"Yamagata 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