{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,1]],"date-time":"2026-08-01T09:40:07Z","timestamp":1785577207689,"version":"3.56.0"},"reference-count":21,"publisher":"Wiley","issue":"s1","license":[{"start":{"date-parts":[[2013,10,17]],"date-time":"2013-10-17T00:00:00Z","timestamp":1381968000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Veterinary Ophthalmology"],"published-print":{"date-parts":[[2014,7]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Objective<\/jats:title><jats:p>To study the equine deep stromal abscesses (<jats:styled-content style=\"fixed-case\">DSA<\/jats:styled-content>) with focus on the duration of the corneal disease, medical treatment, season of presentation, clinical appearance, and the degree of corneal vascularization.<\/jats:p><\/jats:sec><jats:sec><jats:title>Material and Methods<\/jats:title><jats:p>Equine<jats:styled-content style=\"fixed-case\">DSA<\/jats:styled-content>diagnosed, biopsied, and surgically treated at the<jats:styled-content style=\"fixed-case\">U<\/jats:styled-content>niversity of<jats:styled-content style=\"fixed-case\">F<\/jats:styled-content>lorida<jats:styled-content style=\"fixed-case\">V<\/jats:styled-content>eterinary<jats:styled-content style=\"fixed-case\">M<\/jats:styled-content>edical<jats:styled-content style=\"fixed-case\">C<\/jats:styled-content>enter (<jats:styled-content style=\"fixed-case\">UFVMC<\/jats:styled-content>) from 2004 to 2009 were identified. The medical record, clinical photographic images, and microbiology results for each case were evaluated. Frequency and prevalence calculation as well as qualitative data analysis was performed for clinical and microbiological data.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Fifty\u2010one equine<jats:styled-content style=\"fixed-case\">DSA<\/jats:styled-content>were included in the study. Spring (<jats:styled-content style=\"fixed-case\">M<\/jats:styled-content>arch,<jats:styled-content style=\"fixed-case\">A<\/jats:styled-content>pril,<jats:styled-content style=\"fixed-case\">M<\/jats:styled-content>ay; 33.4%) and winter (<jats:styled-content style=\"fixed-case\">D<\/jats:styled-content>ecember,<jats:styled-content style=\"fixed-case\">J<\/jats:styled-content>anuary,<jats:styled-content style=\"fixed-case\">F<\/jats:styled-content>ebruary; 31.4%) were the most common seasons for<jats:styled-content style=\"fixed-case\">DSA<\/jats:styled-content>presentation. The 51 cases were divided into four categories of focal opacity from their clinical appearance: focal yellow (45.2%), focal white (23.5%), diffuse yellow\/white (23.5%), and focal pink (7.8%). 5.9% of the<jats:styled-content style=\"fixed-case\">DSA<\/jats:styled-content>(<jats:italic>n<\/jats:italic>\u00a0=\u00a03) were culture positive for fungal growth, whereas 17.6% were positive for bacterial growth (<jats:italic>n<\/jats:italic>\u00a0=\u00a09). No association between short\u2010\/long\u2010term systemically administered<jats:styled-content style=\"fixed-case\">NSAID<\/jats:styled-content>treatment and the corneal vascular response to the corneal lesion could be appreciated.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>Equine<jats:styled-content style=\"fixed-case\">DSA<\/jats:styled-content>most often present in the spring and winter in the subtropical environment of the state of<jats:styled-content style=\"fixed-case\">F<\/jats:styled-content>lorida (<jats:styled-content style=\"fixed-case\">USA<\/jats:styled-content>). The clinical appearance may have a connection with the etiology and pathogenesis of the equine<jats:styled-content style=\"fixed-case\">DSA<\/jats:styled-content>. No connection between short\u2010 or long\u2010term systemically administered<jats:styled-content style=\"fixed-case\">NSAID<\/jats:styled-content>and the degree of corneal vascularization of the<jats:styled-content style=\"fixed-case\">DSA<\/jats:styled-content>was noted.<\/jats:p><\/jats:sec>","DOI":"10.1111\/vop.12103","type":"journal-article","created":{"date-parts":[[2013,10,17]],"date-time":"2013-10-17T07:32:43Z","timestamp":1381995163000},"page":"6-13","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":18,"title":["Equine deep stromal abscesses (51 cases \u2013 2004\u20132009) \u2013<scp>P<\/scp>art 1: the clinical aspects with attention to the duration of the corneal disease, treatment history, clinical appearance, and microbiology results"],"prefix":"10.1111","volume":"17","author":[{"given":"Michala","family":"de Linde Henriksen","sequence":"first","affiliation":[{"name":"Faculty of Health and Medical Sciences Department of Veterinary Clinical and Animal Sciences University of Copenhagen Frederiksberg Denmark"},{"name":"Departments of Large and Small Animal Clinical Sciences College of Veterinary Medicine University of Florida Gainesville FL USA"},{"name":"Department of Veterinary Clinical Sciences, Comparative Ophthalmology College of Veterinary Medicine University of Minnesota Saint Paul MN USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pia H.","family":"Andersen","sequence":"additional","affiliation":[{"name":"Faculty of Veterinary Medicine and Animal Science Department of Clinical Sciences Swedish University of Agricultural Sciences Uppsala Sweden"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Preben D.","family":"Thomsen","sequence":"additional","affiliation":[{"name":"Faculty of Health and Medical Sciences Department of Veterinary Clinical and Animal Sciences University of Copenhagen Frederiksberg Denmark"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Caryn E.","family":"Plummer","sequence":"additional","affiliation":[{"name":"Departments of Large and Small Animal Clinical Sciences College of Veterinary Medicine University of Florida Gainesville FL USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Brendan","family":"Mangan","sequence":"additional","affiliation":[{"name":"Departments of Large and Small Animal Clinical Sciences College of Veterinary Medicine University of Florida Gainesville FL USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Steffen","family":"Heegaard","sequence":"additional","affiliation":[{"name":"Department of Ophthalmology Glostrup Hospital University of Copenhagen Frederiksberg Denmark"},{"name":"Department of Neuroscience and Pharmacology Eye Pathology Institute University of Copenhagen Frederiksberg Denmark"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nils","family":"Toft","sequence":"additional","affiliation":[{"name":"Faculty of Health and Medical Sciences Department of Large Animal Sciences University of Copenhagen Frederiksberg Denmark"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dennis E.","family":"Brooks","sequence":"additional","affiliation":[{"name":"Departments of Large and Small Animal Clinical Sciences College of Veterinary Medicine University of Florida Gainesville FL USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2013,10,17]]},"reference":[{"key":"e_1_2_7_2_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.2042-3306.1994.tb04048.x"},{"key":"e_1_2_7_3_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.2042-3306.1995.tb04425.x"},{"key":"e_1_2_7_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.cveq.2004.04.007"},{"key":"e_1_2_7_5_1","first-page":"1165","volume-title":"Veterinary Ophthalmology","author":"Brooks DE","year":"2007"},{"key":"e_1_2_7_6_1","doi-asserted-by":"crossref","first-page":"138","DOI":"10.2460\/ajvr.1998.59.02.138","article-title":"Antimicrobial susceptibility patterns of fungi isolated from horses with ulcerative keratomycosis","volume":"59","author":"Brooks DE","year":"1998","journal-title":"American Journal of Veterinary Research"},{"key":"e_1_2_7_7_1","doi-asserted-by":"publisher","DOI":"10.1136\/vr.156.1.13"},{"key":"e_1_2_7_8_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1463-5224.2012.01004.x"},{"key":"e_1_2_7_9_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1463-5224.2008.00654.x"},{"key":"e_1_2_7_10_1","doi-asserted-by":"publisher","DOI":"10.1046\/j.1463-5224.2000.3230145.x"},{"key":"e_1_2_7_11_1","first-page":"2","article-title":"Equine keratomycosis: clinical and laboratory findings in 23 cases","volume":"3","author":"Grahn B","year":"1993","journal-title":"Veteterinary and Comparative Ophthalmology"},{"key":"e_1_2_7_12_1","doi-asserted-by":"publisher","DOI":"10.1111\/vop.12102"},{"key":"e_1_2_7_13_1","doi-asserted-by":"publisher","DOI":"10.1186\/cc2428"},{"key":"e_1_2_7_14_1","doi-asserted-by":"publisher","DOI":"10.1167\/iovs.07-1527"},{"key":"e_1_2_7_15_1","first-page":"1","article-title":"Equine keratomycosis in Switzerland: a retrospective evaluation of 35 horses (January 2000\u2010August 2011)","volume":"2013","author":"Voelter\u2010Ratson K","year":"2011","journal-title":"Equine Veterinary Journal"},{"key":"e_1_2_7_16_1","doi-asserted-by":"publisher","DOI":"10.2307\/3755321"},{"key":"e_1_2_7_17_1","doi-asserted-by":"crossref","first-page":"677","DOI":"10.2460\/javma.1982.181.07.677","article-title":"Corneal stromal abscesses in the horse","volume":"181","author":"Rebhun WC","year":"1982","journal-title":"Journal of American Veterinary Medical Association"},{"key":"e_1_2_7_18_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0037660"},{"key":"e_1_2_7_19_1","doi-asserted-by":"publisher","DOI":"10.1136\/bjo.86.7.755"},{"key":"e_1_2_7_20_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1463-5224.2010.00822.x"},{"key":"e_1_2_7_21_1","doi-asserted-by":"publisher","DOI":"10.1136\/bjo.2006.107243"},{"key":"e_1_2_7_22_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1463-5224.2008.00610.x"}],"container-title":["Veterinary Ophthalmology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fvop.12103","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/vop.12103","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,4,30]],"date-time":"2025-04-30T17:21:23Z","timestamp":1746033683000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/vop.12103"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2013,10,17]]},"references-count":21,"journal-issue":{"issue":"s1","published-print":{"date-parts":[[2014,7]]}},"alternative-id":["10.1111\/vop.12103"],"URL":"https:\/\/doi.org\/10.1111\/vop.12103","archive":["Portico"],"relation":{},"ISSN":["1463-5216","1463-5224"],"issn-type":[{"value":"1463-5216","type":"print"},{"value":"1463-5224","type":"electronic"}],"subject":[],"published":{"date-parts":[[2013,10,17]]},"assertion":[{"value":"2013-10-17","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}