{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,18]],"date-time":"2026-08-18T01:22:55Z","timestamp":1787016175698,"version":"build-2736575974"},"reference-count":9,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2013,11,21]],"date-time":"2013-11-21T00:00:00Z","timestamp":1384992000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Veterinary Ophthalmology"],"published-print":{"date-parts":[[2015,3]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>\n                    A 13\u2010month\u2010old Holstein bull was presented for right\u2010sided exophthalmos. Ophthalmologic examination noted that the animal was visual in both eyes, but that the right pupil was persistently dilated and very sluggish to constrict when stimulated with a bright light and that normal ocular motility was absent. Fundic examination of the right eye was normal as was a complete ophthalmologic examination of the left eye. Radiographs at presentation did not reveal the presence of sinusitis or other skull abnormalities. Initial treatment comprised intravenous antibiotics and anti\u2010inflammatories for orbital inflammation over a 14\u2010day period. There was no perceptible change in the appearance or neuro\u2010ophthalmologic examination of the right eye during hospitalization. The animal was discharged to the owner's care, but 3\u00a0weeks later was found recumbent with unilateral strabismus of the left eye and a fixed right pupil. Due to the inability to rise and rapid deterioration, humane euthanasia was performed, and a full postmortem examination, preceded by a\n                    <jats:styled-content style=\"fixed-case\">MRI<\/jats:styled-content>\n                    , was performed that identified abscesses extending bilaterally through the round foramina obliterating the cavernous sinus region, as well as abscessation of the right mandible, right trigeminal neuritis, right\u2010sided sinusitis, and right\u2010sided otitis media. Cavernous sinus syndrome should be considered in cattle with a combination of exophthalmos and neuro\u2010ophthalmologic abnormalities involving cranial nerves\n                    <jats:styled-content style=\"fixed-case\">III<\/jats:styled-content>\n                    ,\n                    <jats:styled-content style=\"fixed-case\">IV<\/jats:styled-content>\n                    ,\n                    <jats:styled-content style=\"fixed-case\">V<\/jats:styled-content>\n                    , and\n                    <jats:styled-content style=\"fixed-case\">VI<\/jats:styled-content>\n                    , whose branches are located within the cavernous sinus.\n                  <\/jats:p>","DOI":"10.1111\/vop.12127","type":"journal-article","created":{"date-parts":[[2013,11,21]],"date-time":"2013-11-21T02:14:05Z","timestamp":1385000045000},"page":"164-167","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":9,"title":["Cavernous sinus syndrome in a holstein bull"],"prefix":"10.1111","volume":"18","author":[{"given":"Sarah I.","family":"Jacob","sequence":"first","affiliation":[{"name":"Department of Medical Sciences 2015 Linden Drive West Madison WI 53706 USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Randi","family":"Drees","sequence":"additional","affiliation":[{"name":"Department of Surgical Sciences 2015 Linden Drive West Madison WI 53706 USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marie E.","family":"Pinkerton","sequence":"additional","affiliation":[{"name":"Department of Pathobiological Sciences School of Veterinary Medicine University of Wisconsin\u2010Madison 2015 Linden Drive West Madison WI 53706 USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ellison M.","family":"Bentley","sequence":"additional","affiliation":[{"name":"Department of Surgical Sciences 2015 Linden Drive West Madison WI 53706 USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Simon F.","family":"Peek","sequence":"additional","affiliation":[{"name":"Department of Medical Sciences 2015 Linden Drive West Madison WI 53706 USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2013,11,21]]},"reference":[{"key":"e_1_2_4_2_1","doi-asserted-by":"publisher","DOI":"10.2460\/javma.2005.226.1105"},{"key":"e_1_2_4_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.tvjl.2006.04.006"},{"key":"e_1_2_4_4_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1740-8261.2000.tb01885.x"},{"key":"e_1_2_4_5_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1740-8261.1997.tb02099.x"},{"key":"e_1_2_4_6_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1939-1676.1996.tb02029.x"},{"key":"e_1_2_4_7_1","doi-asserted-by":"publisher","DOI":"10.1177\/1098612X13505580"},{"key":"e_1_2_4_8_1","first-page":"1611","volume-title":"Veterinary Ophthalmology","author":"Pearce JW","year":"2013"},{"key":"e_1_2_4_9_1","doi-asserted-by":"publisher","DOI":"10.1046\/j.1463-5224.2003.00287.x"},{"key":"e_1_2_4_10_1","first-page":"957","article-title":"A retrospective study of 29 cases of otitis media\/interna in dairy calves","volume":"53","author":"Bernier Gosselin V","year":"2012","journal-title":"Canadian Veterinary Journal"}],"container-title":["Veterinary Ophthalmology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fvop.12127","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/vop.12127","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,10,1]],"date-time":"2023-10-01T10:18:51Z","timestamp":1696155531000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/vop.12127"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2013,11,21]]},"references-count":9,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2015,3]]}},"alternative-id":["10.1111\/vop.12127"],"URL":"https:\/\/doi.org\/10.1111\/vop.12127","archive":["Portico"],"relation":{},"ISSN":["1463-5216","1463-5224"],"issn-type":[{"value":"1463-5216","type":"print"},{"value":"1463-5224","type":"electronic"}],"subject":[],"published":{"date-parts":[[2013,11,21]]},"assertion":[{"value":"2013-11-21","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}