{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,23]],"date-time":"2026-07-23T15:26:53Z","timestamp":1784820413931,"version":"3.55.0"},"reference-count":44,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2014,11,27]],"date-time":"2014-11-27T00:00:00Z","timestamp":1417046400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Veterinary Ophthalmology"],"published-print":{"date-parts":[[2015,11]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Objective<\/jats:title><jats:p>To evaluate the prevalence of keratoconjunctivitis sicca (<jats:styled-content style=\"fixed-case\">KCS<\/jats:styled-content>) in diabetic and nondiabetic dogs following phacoemulsification.<\/jats:p><\/jats:sec><jats:sec><jats:title>Procedures<\/jats:title><jats:p>Medical records were reviewed for signalment, body weight, diabetes status, and<jats:styled-content style=\"fixed-case\">STT<\/jats:styled-content>at the preoperative and all postoperative examinations. A clinical diagnosis of<jats:styled-content style=\"fixed-case\">KCS<\/jats:styled-content>was defined as a<jats:styled-content style=\"fixed-case\">STT<\/jats:styled-content>&lt;15\u00a0mm\/min with compatible clinical signs. Schirmer tear test values and the prevalence of<jats:styled-content style=\"fixed-case\">KCS<\/jats:styled-content>based on<jats:styled-content style=\"fixed-case\">STT<\/jats:styled-content>&lt;15\u00a0mm\/min were evaluated at 2\u20134, 5\u20138, 9\u201314, 15\u201320, and 41\u201352\u00a0weeks postoperatively. Size of dog (large, &gt;10\u00a0kg; small, \u226410\u00a0kg) and<jats:styled-content style=\"fixed-case\">STT<\/jats:styled-content>ranges (&lt;15\u00a0mm\/min, 15\u201322\u00a0mm\/min and &gt;22\u00a0mm\/min) were categorized for analysis of effect of body weight and<jats:styled-content style=\"fixed-case\">STT<\/jats:styled-content>on prevalence of<jats:styled-content style=\"fixed-case\">KCS<\/jats:styled-content>.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>One hundred and seventeen nondiabetic (198 eyes) and 118 diabetic dogs (228 eyes) were evaluated.<jats:styled-content style=\"fixed-case\">KCS<\/jats:styled-content>was diagnosed in nearly twice as many diabetics as nondiabetics (27.4% vs. 15.4%) within 2\u00a0weeks postoperatively (<jats:italic>P\u00a0<\/jats:italic>=<jats:italic>\u00a0<\/jats:italic>0.0088). Percentage of eyes with<jats:styled-content style=\"fixed-case\">KCS<\/jats:styled-content>among all dogs decreased over time and did not differ significantly after the first postoperative visit. Diabetic small dogs were 1.7 times more likely to have<jats:styled-content style=\"fixed-case\">KCS<\/jats:styled-content>than nondiabetic small dogs (<jats:italic>P\u00a0<\/jats:italic>=<jats:italic>\u00a0<\/jats:italic>0.0052). Preoperative<jats:styled-content style=\"fixed-case\">STT<\/jats:styled-content>was significantly associated with likelihood of postoperative<jats:styled-content style=\"fixed-case\">KCS<\/jats:styled-content>among large (<jats:italic>P\u00a0<\/jats:italic>&lt;<jats:italic>\u00a0<\/jats:italic>0.0001), but not small dogs (<jats:italic>P\u00a0<\/jats:italic>=<jats:italic>\u00a0<\/jats:italic>0.0781). Among large dogs, eyes with<jats:styled-content style=\"fixed-case\">STT<\/jats:styled-content>s between 15 and 22\u00a0mm\/min were approximately 3 times more likely to be diagnosed with<jats:styled-content style=\"fixed-case\">KCS<\/jats:styled-content>after surgery than those with<jats:styled-content style=\"fixed-case\">STT<\/jats:styled-content>&gt;22\u00a0mm\/min.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>The greatest risk for<jats:styled-content style=\"fixed-case\">KCS<\/jats:styled-content>for all dogs is during the first 2\u00a0weeks postoperatively. Populations at greatest risk for postoperative<jats:styled-content style=\"fixed-case\">KCS<\/jats:styled-content>are small dogs, small diabetic dogs, and large dogs with preoperative<jats:styled-content style=\"fixed-case\">STT<\/jats:styled-content>\u226422.<\/jats:p><\/jats:sec>","DOI":"10.1111\/vop.12238","type":"journal-article","created":{"date-parts":[[2014,11,27]],"date-time":"2014-11-27T09:53:02Z","timestamp":1417081982000},"page":"472-480","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":19,"title":["Retrospective study of the prevalence of keratoconjunctivitis sicca in diabetic and nondiabetic dogs after phacoemulsification"],"prefix":"10.1111","volume":"18","author":[{"given":"Anne J.","family":"Gemensky\u2010Metzler","sequence":"first","affiliation":[{"name":"The Ohio State University College of Veterinary Medicine 601 Vernon L. 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