{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,13]],"date-time":"2026-02-13T06:12:14Z","timestamp":1770963134191,"version":"3.50.1"},"reference-count":56,"publisher":"Wiley","issue":"S1","license":[{"start":{"date-parts":[[2015,11,12]],"date-time":"2015-11-12T00:00:00Z","timestamp":1447286400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Veterinary Ophthalmology"],"published-print":{"date-parts":[[2016,7]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Objective<\/jats:title><jats:p>To investigate the causes of endogenous uveitis in cats presenting to referral ophthalmology clinics in North Carolina.<\/jats:p><\/jats:sec><jats:sec><jats:title>Procedure<\/jats:title><jats:p>Medical records of cats diagnosed with endogenous uveitis at North Carolina State University's College of Veterinary Medicine (<jats:styled-content style=\"fixed-case\">NCSU<\/jats:styled-content>\u2010<jats:styled-content style=\"fixed-case\">CVM<\/jats:styled-content>) or Animal Eye Care Associates of Cary,<jats:styled-content style=\"fixed-case\">NC<\/jats:styled-content>between 2003 and 2015 were reviewed. Inclusion criteria were cats that had complete diagnostic workups, including clinical, clinicopathological, serological, and histopathological data, as well as imaging modalities. Serology was consistently completed for feline leukemia virus (Fe<jats:styled-content style=\"fixed-case\">LV<\/jats:styled-content>), feline immunodeficiency virus (<jats:styled-content style=\"fixed-case\">FIV<\/jats:styled-content>), feline coronavirus (<jats:styled-content style=\"fixed-case\">FC<\/jats:styled-content>oV), Toxoplasma gondii, and Bartonella spp.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>One hundred and twenty cats met the inclusion criteria. Seroprevalence of Fe<jats:styled-content style=\"fixed-case\">LV<\/jats:styled-content>(2.7%),<jats:styled-content style=\"fixed-case\">FIV<\/jats:styled-content>(7.3%),<jats:styled-content style=\"fixed-case\">FC<\/jats:styled-content>oV (34.7%),<jats:italic>T. gondii<\/jats:italic>(23.7%), and Bartonella spp. (43.2%) was observed, with a combined seroprevalence of 59.2%. Nineteen cats (15.8%) were diagnosed with feline infectious peritonitis (<jats:styled-content style=\"fixed-case\">FIP<\/jats:styled-content>) based on clinical, hematological, serological, histopathological, and necropsy findings. The average age of all cases was 7.62 years, while the average age of cats diagnosed with<jats:styled-content style=\"fixed-case\">FIP<\/jats:styled-content>was 1.82 years. Neoplasia was diagnosed in six cats (5.0%). No underlying etiology was found in 49 cats (40.8%).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>Both idiopathic and neoplastic causes of uveitis were less prevalent than previously reported in studies, while seropositivity was higher than previously reported for the study area. This may be due to improved diagnostic capabilities or that cats with infectious disease were more likely to be referred. Because of the high prevalence of<jats:styled-content style=\"fixed-case\">FIP<\/jats:styled-content>, young cats with uveitis should be evaluated for hyperglobulinemia and<jats:styled-content style=\"fixed-case\">FC<\/jats:styled-content>oV serology should be performed as minimal diagnostics.<\/jats:p><\/jats:sec>","DOI":"10.1111\/vop.12324","type":"journal-article","created":{"date-parts":[[2015,11,12]],"date-time":"2015-11-12T08:12:44Z","timestamp":1447315964000},"page":"30-37","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":30,"title":["Causes of endogenous uveitis in cats presented to referral clinics in North Carolina"],"prefix":"10.1111","volume":"19","author":[{"given":"Maggie R.","family":"Jinks","sequence":"first","affiliation":[{"name":"College of Veterinary Medicine NCSU\u2010CVM Clinical Sciences Raleigh NC USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Robert 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