{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,15]],"date-time":"2026-07-15T00:28:00Z","timestamp":1784075280539,"version":"3.55.0"},"reference-count":30,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2016,1,15]],"date-time":"2016-01-15T00:00:00Z","timestamp":1452816000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"publisher","award":["K08EY021142"],"award-info":[{"award-number":["K08EY021142"]}],"id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Veterinary Ophthalmology"],"published-print":{"date-parts":[[2017,1]]},"abstract":"Abstract<\/jats:title>Objective<\/jats:title>To compare signalment, presentation, treatment, and outcome in horses diagnosed with corneal degeneration (CD<\/jats:styled-content>) or calcific band keratopathy (CBK<\/jats:styled-content>) at a referral hospital.<\/jats:p><\/jats:sec>Animals studied<\/jats:title>Sixty\u2010nine horses (87 eyes) diagnosed with either CD<\/jats:styled-content> or CBK<\/jats:styled-content>.<\/jats:p><\/jats:sec>Procedures<\/jats:title>Medical records of horses diagnosed with CD<\/jats:styled-content> or CBK<\/jats:styled-content> at the University of California\u2010Davis Veterinary Medical Teaching Hospital (UCD<\/jats:styled-content>\u2010VMTH<\/jats:styled-content>) between 2000 and 2013 were reviewed. Signalment, concurrent ophthalmic diagnoses, previous therapies, diagnostic tests, systemic diagnoses, treatment, follow\u2010up, and outcomes were compared between horses diagnosed with CD<\/jats:styled-content> or CBK<\/jats:styled-content>. Age, breed, and gender were compared between the CD<\/jats:styled-content>\/CBK<\/jats:styled-content> and UCD<\/jats:styled-content>\u2010VMTH<\/jats:styled-content> populations.<\/jats:p><\/jats:sec>Results<\/jats:title>Thirty\u2010three horses (42 eyes) and 36 horses (45 eyes) were diagnosed with CD<\/jats:styled-content> and CBK<\/jats:styled-content>, respectively. Horses with CD<\/jats:styled-content> or CBK<\/jats:styled-content> were significantly older (P<\/jats:italic> < 0.001) than the UCD<\/jats:styled-content>\u2010VMTH<\/jats:styled-content> population with a median age of 16 or 18 years, respectively. Appaloosas were significantly overrepresented in the CD<\/jats:styled-content>\/CBK<\/jats:styled-content> population (33%) in comparison with the UCD<\/jats:styled-content>\u2010VMTH<\/jats:styled-content> population (1.8%, P<\/jats:italic> < 0.001). Equine recurrent uveitis was concurrently diagnosed in 67% and 84% of horses with CD<\/jats:styled-content> or CBK<\/jats:styled-content>, respectively. Pituitary pars intermedia dysfunction (PPID<\/jats:styled-content>) was diagnosed significantly less often in horses with CD<\/jats:styled-content> vs. CBK<\/jats:styled-content> (P<\/jats:italic> = 0.03). Chemical chelation with ethylenediaminetetraacetic acid was performed significantly less frequently in horses diagnosed with CD<\/jats:styled-content> (7.1%) vs. CBK<\/jats:styled-content> (31.1% of eyes) (P<\/jats:italic> = 0.012).<\/jats:p><\/jats:sec>Conclusions<\/jats:title>Despite some differences, equine CD<\/jats:styled-content> and CBK<\/jats:styled-content> are relatively similar conditions and may represent a continuum of disease severity. Horses with PPID<\/jats:styled-content> should be monitored closely for corneal disease including CBK<\/jats:styled-content>.<\/jats:p><\/jats:sec>","DOI":"10.1111\/vop.12338","type":"journal-article","created":{"date-parts":[[2016,1,16]],"date-time":"2016-01-16T21:48:15Z","timestamp":1452980895000},"page":"16-26","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":14,"title":["Comparison of corneal degeneration and calcific band keratopathy from 2000 to 2013 in 69 horses"],"prefix":"10.1111","volume":"20","author":[{"given":"Emily H.","family":"Berryhill","sequence":"first","affiliation":[{"name":"Veterinary Medical Teaching Hospital University of California\u2010Davis Davis CA 95616 USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sara M.","family":"Thomasy","sequence":"additional","affiliation":[{"name":"Department of Surgical and Radiological Sciences University of California\u2010Davis Davis CA 95616 USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Philip H.","family":"Kass","sequence":"additional","affiliation":[{"name":"Department of Population Health and Reproduction University of California\u2010Davis Davis CA 95616 USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Christopher M.","family":"Reilly","sequence":"additional","affiliation":[{"name":"Department of Pathology, Microbiology and Immunology School of Veterinary Medicine University of California\u2010Davis Davis CA 95616 USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kathryn L.","family":"Good","sequence":"additional","affiliation":[{"name":"Department of Surgical and Radiological Sciences University of California\u2010Davis Davis CA 95616 USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Steven R.","family":"Hollingsworth","sequence":"additional","affiliation":[{"name":"Department of Surgical and Radiological Sciences University of California\u2010Davis Davis CA 95616 USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"David J.","family":"Maggs","sequence":"additional","affiliation":[{"name":"Department of Surgical and Radiological Sciences University of California\u2010Davis Davis CA 95616 USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"K. 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