{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,21]],"date-time":"2026-08-21T12:15:28Z","timestamp":1787314528578,"version":"build-2736575974"},"reference-count":26,"publisher":"Wiley","issue":"S1","license":[{"start":{"date-parts":[[2016,1,22]],"date-time":"2016-01-22T00:00:00Z","timestamp":1453420800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/100003516","name":"Winn Feline Foundation","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100003516","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"publisher","award":["P30 EY12576"],"award-info":[{"award-number":["P30 EY12576"]}],"id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Veterinary Ophthalmology"],"published-print":{"date-parts":[[2016,7]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Objective<\/jats:title>\n                    <jats:p>\n                      The aim of this study was to evaluate goblet cell density (\n                      <jats:styled-content style=\"fixed-case\">GCD<\/jats:styled-content>\n                      ) and distribution in cats without clinical evidence of ocular surface disease and without histologic evidence of conjunctival disease.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Animals studied<\/jats:title>\n                    <jats:p>Fourteen Domestic Shorthair cats euthanized for reasons unrelated to this study.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Procedures<\/jats:title>\n                    <jats:p>\n                      Before euthanasia, cats were verified using slit\u2010lamp biomicroscopy and fluorescein staining to be free of eyelid or ocular surface abnormalities. Immediately after euthanasia, bilateral conjunctival specimens including third eyelid (\n                      <jats:styled-content style=\"fixed-case\">TEL<\/jats:styled-content>\n                      ) were collected, routinely processed, and stained with periodic acid\u2013Schiff and hematoxylin and eosin. Thirteen conjunctival regions were identified. For each region,\n                      <jats:styled-content style=\"fixed-case\">GCD<\/jats:styled-content>\n                      was expressed as the percentage of goblet cells\/200 basal epithelial cells.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      Mean\n                      <jats:styled-content style=\"fixed-case\">GCD<\/jats:styled-content>\n                      ranged widely by region: anterior surface of the\n                      <jats:styled-content style=\"fixed-case\">TEL<\/jats:styled-content>\n                      = 48.8%, fornicial regions = 47.0%, palpebral regions = 38.5%, bulbar regions = 19.6%, and posterior surface of the\n                      <jats:styled-content style=\"fixed-case\">TEL<\/jats:styled-content>\n                      = 12.6%. The anterior surface of the\n                      <jats:styled-content style=\"fixed-case\">TEL<\/jats:styled-content>\n                      had significantly higher\n                      <jats:styled-content style=\"fixed-case\">GCD<\/jats:styled-content>\n                      than did the bulbar and the palpebral regions, but not the fornicial regions. Bulbar conjunctiva had significantly lower\n                      <jats:styled-content style=\"fixed-case\">GCD<\/jats:styled-content>\n                      than did all other conjunctival regions except the posterior surface of the\n                      <jats:styled-content style=\"fixed-case\">TEL<\/jats:styled-content>\n                      . No significant difference was noted between\n                      <jats:styled-content style=\"fixed-case\">GCD<\/jats:styled-content>\n                      of male versus female cats, dorsal versus ventral regions, or lateral versus medial regions.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>\n                      Although conjunctival\n                      <jats:styled-content style=\"fixed-case\">GCD<\/jats:styled-content>\n                      ranged widely by region, the anterior surface of the\n                      <jats:styled-content style=\"fixed-case\">TEL<\/jats:styled-content>\n                      appears to be an excellent location for assessing conjunctival goblet cells in cats because this area has high\n                      <jats:styled-content style=\"fixed-case\">GCD<\/jats:styled-content>\n                      and is more readily accessible than is the palpebral, fornicial, or bulbar conjunctiva.\n                    <\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/vop.12343","type":"journal-article","created":{"date-parts":[[2016,1,22]],"date-time":"2016-01-22T09:02:52Z","timestamp":1453453372000},"page":"38-43","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":21,"title":["Goblet cell density and distribution in cats with clinically and histologically normal conjunctiva"],"prefix":"10.1111","volume":"19","author":[{"given":"Lionel","family":"Sebbag","sequence":"first","affiliation":[{"name":"William R. 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