{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,30]],"date-time":"2025-11-30T09:10:50Z","timestamp":1764493850452},"reference-count":18,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2016,2,12]],"date-time":"2016-02-12T00:00:00Z","timestamp":1455235200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Veterinary Ophthalmology"],"published-print":{"date-parts":[[2017,1]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>This retrospective study identified 12 cases (6 canine and 6 feline) of ocular lymphoma with extensive retinal involvement and relative sparing of other ocular tissues. Our objectives were to describe the morphologic and immunohistochemical features of retinal lymphoma, assess the degree of correlation to the human counterpart, assign subtypes based on the veterinary\u2010adapted <jats:styled-content style=\"fixed-case\">WHO<\/jats:styled-content> classification system, and promote accurate reporting of retinal involvement in cases of intraocular lymphoma. Our findings suggest that a distinct retinal tropism is quite rare, representing approximately 1% of all cases of canine and feline ocular lymphoma. No breed or sex predispositions were identified. The mean age of the affected animal was 7 years (range 4\u201310) and 11 years (range 6\u201319) for dogs and cats, respectively. Nine cases (5 canine and 4 feline) were classified as diffuse large B\u2010cell lymphoma (<jats:styled-content style=\"fixed-case\">DLBCL<\/jats:styled-content>) subtype. The remaining cases were classified as peripheral T\u2010cell lymphoma (<jats:styled-content style=\"fixed-case\">PTCL<\/jats:styled-content>).<\/jats:p>","DOI":"10.1111\/vop.12356","type":"journal-article","created":{"date-parts":[[2016,2,12]],"date-time":"2016-02-12T08:14:40Z","timestamp":1455264880000},"page":"73-78","update-policy":"http:\/\/dx.doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":9,"title":["Canine and feline retinal lymphoma: a retrospective review of 12 cases"],"prefix":"10.1111","volume":"20","author":[{"given":"Jennifer L.","family":"Malmberg","sequence":"first","affiliation":[{"name":"Department of Microbiology, Immunology, and Pathology College of Veterinary Medicine and Biomedical Sciences Colorado State University Fort Collins CO USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Teresa","family":"Garcia","sequence":"additional","affiliation":[{"name":"Department of Microbiology, Immunology, and Pathology College of Veterinary Medicine and Biomedical Sciences Colorado State University Fort Collins CO USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Richard R.","family":"Dubielzig","sequence":"additional","affiliation":[{"name":"Department of Pathobiological Sciences University of Wisconsin School of Veterinary Medicine Madison WI USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"E. J.","family":"Ehrhart","sequence":"additional","affiliation":[{"name":"Department of Microbiology, Immunology, and Pathology College of Veterinary Medicine and Biomedical Sciences Colorado State University Fort Collins CO USA"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2016,2,12]]},"reference":[{"key":"e_1_2_7_2_1","first-page":"699","volume-title":"Withrow and MacEwen's Small Animal Clinical Oncology","author":"Vail DM","year":"2007"},{"key":"e_1_2_7_3_1","first-page":"127","article-title":"Prevalence of ocular involvement in dogs with multicentric lymphoma: prospective evaluation of 94 cases","volume":"4","author":"Krohne S","year":"1994","journal-title":"Vet Comp Ophthamol"},{"key":"e_1_2_7_4_1","unstructured":"MuscianoAR DubielzigRD ACD.Clinical outcoma and histopathological characterization of ocular lymphoma in dogs and cats.2014."},{"key":"e_1_2_7_5_1","first-page":"460","article-title":"Presumed solitary intraocular or conjunctival lymphoma in dogs and cats: 9 cases (1985\u20132013)","volume":"244","author":"Wiggans K","year":"2014","journal-title":"J Vet Med Educ"},{"key":"e_1_2_7_6_1","doi-asserted-by":"publisher","DOI":"10.1080\/09273940903168696"},{"key":"e_1_2_7_7_1","doi-asserted-by":"publisher","DOI":"10.1097\/ICU.0b013e328010948d"},{"key":"e_1_2_7_8_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00417-004-0973-0"},{"key":"e_1_2_7_9_1","first-page":"1","article-title":"Intraocular and periocular lymphoma in dogs and cats: a retrospective review of 21 cases (2001\u20102012)","volume":"14","author":"Ota\u2010Kuroki J","year":"2013","journal-title":"Vet Ophthalmol"},{"key":"e_1_2_7_10_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1399-0039.1994.tb02324.x"},{"key":"e_1_2_7_11_1","first-page":"309","article-title":"Immunophenotypic classification of canine malignant lymphoma on formalin\u2010mixed paraffin wax\u2010embedded tissue by means of CD3 and CD79a cell markers","volume":"63","author":"Milner R","year":"1996","journal-title":"Onderstepoort J Vet Res"},{"key":"e_1_2_7_12_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.vetimm.2008.11.019"},{"key":"e_1_2_7_13_1","volume-title":"World Health Organization Classification of Tumours of Haematopoietic and Lymphoid Tissues","author":"Swerdlow S","year":"2008"},{"key":"e_1_2_7_14_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.vetimm.2011.06.016"},{"key":"e_1_2_7_15_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00417-004-0890-2"},{"key":"e_1_2_7_16_1","doi-asserted-by":"publisher","DOI":"10.1038\/modpathol.3880265"},{"key":"e_1_2_7_17_1","first-page":"183134","article-title":"Peripheral T\u2010cell lymphoma with aberrant expression of CD19, CD20, and CD79a: case report and literature review","volume":"2013","author":"Matnani RG","year":"2013","journal-title":"Case Rep Hematol"},{"key":"e_1_2_7_18_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2141.1992.tb08169.x"},{"key":"e_1_2_7_19_1","doi-asserted-by":"publisher","DOI":"10.1167\/iovs.04-0869"}],"container-title":["Veterinary Ophthalmology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fvop.12356","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fvop.12356","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/vop.12356","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,10,1]],"date-time":"2023-10-01T17:40:42Z","timestamp":1696182042000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/vop.12356"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2016,2,12]]},"references-count":18,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2017,1]]}},"alternative-id":["10.1111\/vop.12356"],"URL":"https:\/\/doi.org\/10.1111\/vop.12356","archive":["Portico"],"relation":{},"ISSN":["1463-5216","1463-5224"],"issn-type":[{"value":"1463-5216","type":"print"},{"value":"1463-5224","type":"electronic"}],"subject":[],"published":{"date-parts":[[2016,2,12]]},"assertion":[{"value":"2016-02-12","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}