{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,1]],"date-time":"2025-10-01T16:23:04Z","timestamp":1759335784771,"version":"3.41.0"},"reference-count":24,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2016,3,4]],"date-time":"2016-03-04T00:00:00Z","timestamp":1457049600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Veterinary Ophthalmology"],"published-print":{"date-parts":[[2017,3]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Objectives<\/jats:title><jats:p>To report the prevalence and clinical characteristics of an open\u2010angle glaucoma in Petit Basset Griffon Vendeen (<jats:styled-content style=\"fixed-case\">PBGV<\/jats:styled-content>) dogs in the United Kingdom (<jats:styled-content style=\"fixed-case\">UK<\/jats:styled-content>).<\/jats:p><\/jats:sec><jats:sec><jats:title>Animals studied and methods<\/jats:title><jats:p>At breed society clinics extending over a 6\u2010year period, 366 dogs of varying ages and both sexes were clinically examined for signs of glaucoma using slit\u2010lamp biomicroscopy, indirect and direct ophthalmoscopy, tonometry, and gonioscopy.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>The prevalence of glaucoma was 10.4% (38 dogs). Clinical signs of the disease presented from 3 years of age onwards, the commonest initial feature being the elevation of intraocular pressure (<jats:styled-content style=\"fixed-case\">IOP<\/jats:styled-content>) in 15 dogs (39.4%). In addition to elevated<jats:styled-content style=\"fixed-case\">IOP<\/jats:styled-content>, another 13 dogs (34.2%) presented with other features of glaucoma, some with lens subluxation and globe enlargement and all with possible or known vision defects. In the remaining 10 dogs (26.3%), phacodonesis or lens subluxation was observed before subsequent elevation of<jats:styled-content style=\"fixed-case\">IOP<\/jats:styled-content>.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>High prevalence and similarity to the primary open\u2010angle glaucoma (<jats:styled-content style=\"fixed-case\">POAG<\/jats:styled-content>) seen in the Beagle and Elkhound breeds indicate that an open\u2010angle glaucoma is present in the<jats:styled-content style=\"fixed-case\">PBGV<\/jats:styled-content>in the<jats:styled-content style=\"fixed-case\">UK<\/jats:styled-content>and that this disease may be genetically determined in this breed. Although increased<jats:styled-content style=\"fixed-case\">IOP<\/jats:styled-content>is the commonest early diagnostic feature, lens instability prior to an increase in<jats:styled-content style=\"fixed-case\">IOP<\/jats:styled-content>may be part of the clinical picture.<\/jats:p><\/jats:sec>","DOI":"10.1111\/vop.12369","type":"journal-article","created":{"date-parts":[[2016,3,6]],"date-time":"2016-03-06T06:17:35Z","timestamp":1457245055000},"page":"98-102","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":10,"title":["Open\u2010angle glaucoma in the Petit Basset Griffon Vendeen"],"prefix":"10.1111","volume":"20","author":[{"given":"Peter G. C.","family":"Bedford","sequence":"first","affiliation":[{"name":"Professor Emeritus of Veterinary Ophthalmology Royal Veterinary College London UK"},{"name":"Ophthalmology Referrals 25, Great North Road, Brookmans Park Herts. 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