{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,9]],"date-time":"2026-03-09T00:14:56Z","timestamp":1773015296397,"version":"3.50.1"},"reference-count":37,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2016,4,7]],"date-time":"2016-04-07T00:00:00Z","timestamp":1459987200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Veterinary Ophthalmology"],"published-print":{"date-parts":[[2017,3]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Purpose<\/jats:title><jats:p>To determine the significance of<jats:italic>Aspergillus<\/jats:italic>and<jats:italic>Fusarium<\/jats:italic>spp., as identified by culture, on clinical outcome in equine keratomycosis.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Retrospective analysis of 66 horses (66 eyes) evaluated at the NCSU\u2010VH diagnosed with keratomycosis from which<jats:italic>Aspergillus<\/jats:italic>or<jats:italic>Fusarium<\/jats:italic>spp. were cultured. Horses were classified into those who improved with medical management alone or those who required surgical intervention to improve. Horses who underwent surgery were divided into globe\u2010sparing procedures or enucleation. Effects of bacterial co\u2010infection, previous topical steroid or antifungal use, and time of year on fungal genus and outcome were evaluated.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p><jats:italic>Aspergillus<\/jats:italic>spp. was cultured from 41 eyes (63%), while 24 eyes (37%) cultured<jats:italic>Fusarium<\/jats:italic>spp. One horse cultured both species and was not included in further evaluation. From the horses that cultured<jats:italic>Aspergillus<\/jats:italic>spp., 28 eyes (68%) required surgical intervention to control the infection: 21 (75%) of these eyes maintained globe integrity, while 7 eyes (25%) were enucleated. Of those horses with<jats:italic>Fusarium<\/jats:italic>spp., 14 eyes (58%) required surgical intervention: 11 (79%) of these eyes maintained globe integrity, while 3 eyes (21%) were enucleated. Genus of fungus cultured was not significantly associated with the need for surgical intervention nor was it significantly associated with the necessity of globe\u2010sparing surgery versus enucleation. Additionally, bacterial co\u2010infection, previous steroidal or antifungal use, and time of year did not affect outcome or type of fungal species cultured.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>Equine keratomycosis from<jats:italic>Fusarium<\/jats:italic>spp. compared to keratomycosis from<jats:italic>Aspergillus<\/jats:italic>spp. is not associated with a different clinical outcome.<\/jats:p><\/jats:sec>","DOI":"10.1111\/vop.12381","type":"journal-article","created":{"date-parts":[[2016,4,10]],"date-time":"2016-04-10T17:39:30Z","timestamp":1460309970000},"page":"140-146","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":30,"title":["Impact of fungal species cultured on outcome in horses with fungal keratitis"],"prefix":"10.1111","volume":"20","author":[{"given":"Amanda B.","family":"Sherman","sequence":"first","affiliation":[{"name":"Department of Clinical Sciences College of Veterinary Medicine North Carolina State University 1052 William Moore Dr Raleigh NC 27607 USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Alison B.","family":"Clode","sequence":"additional","affiliation":[{"name":"Department of Clinical Sciences College of Veterinary Medicine North Carolina State University 1052 William Moore Dr Raleigh NC 27607 USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Brian C.","family":"Gilger","sequence":"additional","affiliation":[{"name":"Department of Clinical Sciences College of Veterinary Medicine North Carolina State University 1052 William Moore Dr Raleigh NC 27607 USA"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2016,4,7]]},"reference":[{"key":"e_1_2_5_2_1","doi-asserted-by":"publisher","DOI":"10.2460\/ajvr.67.2.296"},{"key":"e_1_2_5_3_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.2042-3292.1998.tb00856.x"},{"key":"e_1_2_5_4_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.2042-3306.1998.tb04469.x"},{"key":"e_1_2_5_5_1","doi-asserted-by":"publisher","DOI":"10.2746\/095777309X400289"},{"key":"e_1_2_5_6_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1463-5224.2012.01031.x"},{"key":"e_1_2_5_7_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1463-5224.2009.00721.x"},{"key":"e_1_2_5_8_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.2042-3306.1983.tb04578.x"},{"key":"e_1_2_5_9_1","doi-asserted-by":"publisher","DOI":"10.1111\/vop.12004"},{"key":"e_1_2_5_10_1","doi-asserted-by":"publisher","DOI":"10.1038\/sj.eye.6700557"},{"key":"e_1_2_5_11_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.2042-3292.2012.00440.x"},{"key":"e_1_2_5_12_1","doi-asserted-by":"publisher","DOI":"10.2460\/javma.231.7.1086"},{"key":"e_1_2_5_13_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.2042-3306.2012.00623.x"},{"key":"e_1_2_5_14_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1469-0691.2004.00909.x"},{"key":"e_1_2_5_15_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.2042-3306.1983.tb04556.x"},{"key":"e_1_2_5_16_1","doi-asserted-by":"publisher","DOI":"10.1046\/j.0933-7407.2003.00936.x"},{"key":"e_1_2_5_17_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ophtha.2010.09.011"},{"key":"e_1_2_5_18_1","volume-title":"Equine Ophthalmology 2nd edition","author":"Gilger BC","year":"2011"},{"key":"e_1_2_5_19_1","doi-asserted-by":"publisher","DOI":"10.2746\/095777309X478"},{"key":"e_1_2_5_20_1","doi-asserted-by":"publisher","DOI":"10.2746\/095777309X400270"},{"key":"e_1_2_5_21_1","first-page":"936","article-title":"Equine keratomycosis","volume":"14","author":"Barton MH","year":"1992","journal-title":"Compendium on Continuing Education"},{"key":"e_1_2_5_22_1","doi-asserted-by":"publisher","DOI":"10.1590\/S1517-83822007000400036"},{"key":"e_1_2_5_23_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.phymed.2012.09.007"},{"key":"e_1_2_5_24_1","doi-asserted-by":"publisher","DOI":"10.3402\/iee.v2i0.11591"},{"key":"e_1_2_5_25_1","doi-asserted-by":"publisher","DOI":"10.2746\/0425164054530731"},{"key":"e_1_2_5_26_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1463-5224.2003.00312.x"},{"key":"e_1_2_5_27_1","doi-asserted-by":"crossref","first-page":"105","DOI":"10.2460\/javma.1998.213.01.105","article-title":"Clinical appearances, healing patterns, risk factors, and outcomes of horses with fungal keratitis: 53 cases (1978\u20101996)","volume":"213","author":"Gaarder JE","year":"1998","journal-title":"Journal of the American Veterinary Medical Association"},{"key":"e_1_2_5_28_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.2042-3306.1995.tb04425.x"},{"key":"e_1_2_5_29_1","doi-asserted-by":"publisher","DOI":"10.2460\/ajvr.2005.66.800"},{"key":"e_1_2_5_30_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.2042-3306.2010.tb05630.x"},{"key":"e_1_2_5_31_1","first-page":"331","article-title":"Efficacy of antifungal agents in the cornea II. 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