{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,4]],"date-time":"2026-02-04T16:05:25Z","timestamp":1770221125251,"version":"3.49.0"},"reference-count":30,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2016,7,20]],"date-time":"2016-07-20T00:00:00Z","timestamp":1468972800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Veterinary Ophthalmology"],"published-print":{"date-parts":[[2017,11]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>The objective of this paper is to describe clinical behavior, histopathologic features, and immunohistochemical staining of two\u2010related horses with intraocular teratoid medulloepithelioma. Two\u2010related Quarter Horses with similar intraocular masses presented to the<jats:styled-content style=\"fixed-case\">UF<\/jats:styled-content>\u2010<jats:styled-content style=\"fixed-case\">CVM<\/jats:styled-content>Comparative Ophthalmology Service for evaluation and treatment. The first horse, a 3\u2010year\u2010old gelding, had glaucoma and a cyst\u2010like mass in the anterior chamber. Enucleation was performed. Histopathology revealed a teratoid medulloepithelioma. The tumor was considered to be completely excised. Fifteen months later, the gelding presented with swelling of the enucleated orbit and local lymph nodes with deformation of the skull. Cytology revealed neuroectodermal neoplastic cells. Necropsy confirmed tumor metastasis. Six weeks later, a 9\u2010year\u2010old mare, a full sibling to the gelding, presented for examination. An infiltrative mass of the iris and ciliary body was found that extended into the anterior, posterior, and vitreal chambers. Uveitis was present, but secondary glaucoma was not noted. Enucleation was performed and the histopathologic diagnosis was also teratoid medulloepithelioma. The mare has had no recurrence to date, 2\u00a0years following enucleation. Metastasis of intraocular teratoid medulloepithelioma is possible. Staging is recommended in cases where the diagnosis of teratoid medulloepithelioma is confirmed. Surveillance of full siblings is recommended until more information regarding etiology is known.<\/jats:p>","DOI":"10.1111\/vop.12409","type":"journal-article","created":{"date-parts":[[2016,7,21]],"date-time":"2016-07-21T03:36:51Z","timestamp":1469072211000},"page":"551-559","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":9,"title":["Clinical behavior of intraocular teratoid medulloepithelioma in two\u2010related Quarter Horses"],"prefix":"10.1111","volume":"20","author":[{"given":"Caroline S.","family":"Monk","sequence":"first","affiliation":[{"name":"Department of Small Animal Clinical Sciences College of Veterinary Medicine University of Florida Gainesville FL USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"William F.","family":"Craft","sequence":"additional","affiliation":[{"name":"Department of Infectious Diseases and Pathology College of Veterinary Medicine University of Florida Gainesville FL 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