{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,18]],"date-time":"2026-08-18T01:20:57Z","timestamp":1787016057951,"version":"build-2736575974"},"reference-count":41,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2017,1,11]],"date-time":"2017-01-11T00:00:00Z","timestamp":1484092800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Veterinary Ophthalmology"],"published-print":{"date-parts":[[2018,5]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Objective<\/jats:title>\n                    <jats:p>Corneal ulceration secondary to trauma commonly affects marine mammals, often with opportunistic secondary bacterial or fungal infections. This report characterizes the combined use of auriculopalpebral and ophthalmic nerve blocks, adipose\u2010derived stem cells, and subconjunctival injections for successful treatment of corneal trauma and infection in dolphins.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Animal studied<\/jats:title>\n                    <jats:p>\n                      An 11\u2010year\u2010old, female bottlenose dolphin (\n                      <jats:italic>Tursiops truncatus<\/jats:italic>\n                      ) presented with bilateral diffuse corneal opacities, which progressed to keratomycosis caused by\n                      <jats:italic>Candida albicans<\/jats:italic>\n                      .\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Procedure<\/jats:title>\n                    <jats:p>Aggressive medical management was employed, including the use of subconjunctival injections of adipose\u2010derived stem cells, plasma, topical and oral antifungals and antibiotics, and anti\u2010inflammatory and pain medications. Anesthetic block of the auriculopalpebral and ophthalmic nerves was employed to evaluate the corneas.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>\n                      Subconjunctival injections were employed over 52 days, followed by topical drops for 5 months. At last evaluation, there was no evidence of blepharospasm bilaterally. Only a faint superficial gray corneal opacity remained\n                      <jats:styled-content style=\"fixed-case\">OS<\/jats:styled-content>\n                      . A temporal paraxial corneal opacity was present\n                      <jats:styled-content style=\"fixed-case\">OD<\/jats:styled-content>\n                      , with receding inactive vascularization and a small amount of melanosis temporally.\n                    <\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/vop.12459","type":"journal-article","created":{"date-parts":[[2017,1,11]],"date-time":"2017-01-11T02:19:07Z","timestamp":1484101147000},"page":"298-304","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":5,"title":["Clinical management of\n                    <i>Candida albicans<\/i>\n                    keratomycosis in a bottlenose dolphin (\n                    <i>Tursiops truncatus<\/i>\n                    )"],"prefix":"10.1111","volume":"21","author":[{"given":"Claire A.","family":"Simeone","sequence":"first","affiliation":[{"name":"National Marine Mammal Foundation San Diego CA 92106 USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"John P.","family":"Traversi","sequence":"additional","affiliation":[{"name":"Sunset Cliffs Animal Hospital San Diego CA 92107 USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jenny M.","family":"Meegan","sequence":"additional","affiliation":[{"name":"National Marine Mammal Foundation San Diego CA 92106 USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Carolina","family":"LeBert","sequence":"additional","affiliation":[{"name":"National Marine Mammal Foundation San Diego CA 92106 USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Carmen M. 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