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The dog had acutely developed right\u2010sided periorbital swelling, exophthalmos with pain on retropulsion, as well as multiple cutaneous exudative plaques on the feet and tail base. On ophthalmic examination, the dog also exhibited mild left\u2010sided exophthalmos with decreased, nonpainful retropulsion. Orbital ultrasound and <jats:styled-content style=\"fixed-case\">CT<\/jats:styled-content> were performed to evaluate the extent of bilateral orbital disease. Incisional biopsies were obtained from the affected right periorbital tissues and skin of the feet, and histopathology revealed severe neutrophilic inflammation of the dermis with no organisms detected. Histologic changes were consistent with sterile neutrophilic dermatosis. The dog achieved clinical remission following treatment with initial immunosuppressive doses of corticosteroids and subsequent long\u2010term maintenance therapy using oral cyclosporine.<\/jats:p>","DOI":"10.1111\/vop.12467","type":"journal-article","created":{"date-parts":[[2017,3,15]],"date-time":"2017-03-15T03:52:52Z","timestamp":1489549972000},"page":"530-534","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":6,"title":["Exophthalmos due to sterile neutrophilic dermatosis in a dog"],"prefix":"10.1111","volume":"21","author":[{"given":"Emily K.","family":"Sharpe","sequence":"first","affiliation":[{"name":"Department of Clinical Sciences College of Veterinary Medicine Kansas State University Manhattan KS USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jessica M.","family":"Meekins","sequence":"additional","affiliation":[{"name":"Department of Clinical Sciences College of Veterinary Medicine Kansas State University Manhattan KS USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mary","family":"Bagladi\u2010Swanson","sequence":"additional","affiliation":[{"name":"Department of Clinical Sciences College of Veterinary Medicine Kansas State University Manhattan KS USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Amy J.","family":"Rankin","sequence":"additional","affiliation":[{"name":"Department of Clinical Sciences College of Veterinary Medicine Kansas State University Manhattan KS USA"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2017,3,14]]},"reference":[{"key":"e_1_2_5_2_1","first-page":"793","volume-title":"Veterinary Ophthalmology","author":"Spiess BM","year":"2013"},{"key":"e_1_2_5_3_1","doi-asserted-by":"publisher","DOI":"10.1053\/j.tcam.2015.07.010"},{"key":"e_1_2_5_4_1","doi-asserted-by":"publisher","DOI":"10.1002\/9780470752487"},{"key":"e_1_2_5_5_1","first-page":"1397","article-title":"Canine sterile neutrophilic dermatitis (resembling Sweet's syndrome) in a Dachshund","volume":"51","author":"Gains MJ","year":"2010","journal-title":"Canadian Veterinary Journal"},{"key":"e_1_2_5_6_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-3164.2009.00746.x"},{"key":"e_1_2_5_7_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1748-5827.2006.00209.x"},{"key":"e_1_2_5_8_1","unstructured":"VitaleCB ZengerE HillJ.Putative Rimadyl\u2010induced neutrophilic dermatosis resembling Sweet's syndrome in 2 dogs (abstract). 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