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The orbital mass was excised with preservation of the globe, and adjunctive cryotherapy was performed. A definitive diagnosis of lacrimal gland adenocarcinoma was obtained after histopathologic evaluation and histochemical staining with periodic acid\u2013Schiff and mucicarmine. Thirteen months postoperatively, tumor regrowth occurred with a much larger osteolytic lesion, and a second surgery was performed consisting of tumor excision with implantation of carboplatin\u2010impregnated calcium sulfate hemihydrate beads. The cat has remained free of recurrence 11 months after the second surgery (26 months after initial diagnosis and surgery). A feline orbital lacrimal gland adenocarcinoma was successfully managed utilizing globe\u2010preserving surgical excision with adjunctive cryotherapy and subsequent carboplatin\u2010impregnated bead implantation. Orbital lacrimal gland adenocarcinoma in cats may not be as aggressive as other forms of periocular, head, and neck adenocarcinomas.<\/jats:p>","DOI":"10.1111\/vop.12501","type":"journal-article","created":{"date-parts":[[2017,8,11]],"date-time":"2017-08-11T03:38:41Z","timestamp":1502422721000},"page":"419-425","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":6,"title":["Surgical excision of a feline orbital lacrimal gland adenocarcinoma with adjunctive cryotherapy and carboplatin\u2010impregnated bead implantation"],"prefix":"10.1111","volume":"21","author":[{"given":"Daniel M.","family":"Dorbandt","sequence":"first","affiliation":[{"name":"Department of Veterinary Clinical Medicine College of Veterinary Medicine University of Illinois Urbana\u2010Champaign 1008 W. 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