{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,31]],"date-time":"2026-07-31T22:59:45Z","timestamp":1785538785097,"version":"3.56.0"},"reference-count":38,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2018,3,14]],"date-time":"2018-03-14T00:00:00Z","timestamp":1520985600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Veterinary Ophthalmology"],"published-print":{"date-parts":[[2018,11]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Objective<\/jats:title><jats:p>To evaluate the efficacy of diamond burr debridement (<jats:styled-content style=\"fixed-case\">DBD<\/jats:styled-content>) vs a combination of diamond burr debridement with superficial grid keratotomy (<jats:styled-content style=\"fixed-case\">DBD<\/jats:styled-content>+<jats:styled-content style=\"fixed-case\">SGK<\/jats:styled-content>) for the treatment of spontaneous chronic corneal epithelial defects (<jats:styled-content style=\"fixed-case\">SCCED<\/jats:styled-content>s) in dogs.<\/jats:p><\/jats:sec><jats:sec><jats:title>Procedure<\/jats:title><jats:p>Medical records of dogs diagnosed with <jats:styled-content style=\"fixed-case\">SCCED<\/jats:styled-content>s from three different institutions that received a <jats:styled-content style=\"fixed-case\">DBD<\/jats:styled-content> or <jats:styled-content style=\"fixed-case\">DBD<\/jats:styled-content>+<jats:styled-content style=\"fixed-case\">SGK<\/jats:styled-content> between 2003 and 2015 were reviewed. Age, breed, sex, history of a previous <jats:styled-content style=\"fixed-case\">SCCED<\/jats:styled-content>, procedures performed, time to healing, and complications were statistically analyzed.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>One hundred and ninety\u2010four dogs met the inclusion criteria. Eighty\u2010two of 106 eyes (77.4%) received a <jats:styled-content style=\"fixed-case\">DBD<\/jats:styled-content> and healed following the first treatment (13.3\u00a0\u00b1\u00a04.9\u00a0days to recheck, range 2\u201027). Sixty\u2010eight of 88 eyes (77.3%) received a <jats:styled-content style=\"fixed-case\">DBD<\/jats:styled-content>+<jats:styled-content style=\"fixed-case\">SGK<\/jats:styled-content> and healed following the first treatment (15.4\u00a0\u00b1\u00a05.0\u00a0days to recheck, range 5\u201045). No significant difference in healing outcome was found between the two treatments (<jats:italic>P\u00a0<\/jats:italic>=<jats:italic>\u00a0<\/jats:italic>1). For <jats:styled-content style=\"fixed-case\">SCCED<\/jats:styled-content>s that healed after a single treatment (<jats:italic>n<\/jats:italic>\u00a0=<jats:italic>\u00a0<\/jats:italic>150), complications occurred in 13.3% (<jats:italic>n\u00a0<\/jats:italic>=<jats:italic>\u00a0<\/jats:italic>20) of eyes with no difference in complications between the <jats:styled-content style=\"fixed-case\">DBD<\/jats:styled-content> and <jats:styled-content style=\"fixed-case\">DBD<\/jats:styled-content>+<jats:styled-content style=\"fixed-case\">SGK<\/jats:styled-content> groups (<jats:italic>P\u00a0<\/jats:italic>=<jats:italic>\u00a0<\/jats:italic>.86). Thirty\u2010five of 44 eyes (80.0%) healed after the second treatment (16\u00a0\u00b1\u00a08.2\u00a0days from second treatment to third visit, range 5\u201047); nine of 44 eyes (20.0%) were not healed (12\u00a0\u00b1\u00a06.2\u00a0days from second treatment to third visit, range 5\u201025). The second treatment method did not influence healing rates (<jats:italic>P\u00a0<\/jats:italic>=<jats:italic>\u00a0<\/jats:italic>.64).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p><jats:styled-content style=\"fixed-case\">DBD<\/jats:styled-content> and <jats:styled-content style=\"fixed-case\">DBD<\/jats:styled-content>+<jats:styled-content style=\"fixed-case\">SGK<\/jats:styled-content> are equally effective treatment methods for canine <jats:styled-content style=\"fixed-case\">SCCED<\/jats:styled-content>s. No differences in complication rates after one treatment were observed between <jats:styled-content style=\"fixed-case\">DBD<\/jats:styled-content> and <jats:styled-content style=\"fixed-case\">DBD<\/jats:styled-content>+<jats:styled-content style=\"fixed-case\">SGK<\/jats:styled-content>.<\/jats:p><\/jats:sec>","DOI":"10.1111\/vop.12556","type":"journal-article","created":{"date-parts":[[2018,3,15]],"date-time":"2018-03-15T11:50:33Z","timestamp":1521114633000},"page":"622-631","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":21,"title":["Treatment of spontaneous chronic corneal epithelial defects (SCCEDs) with diamond burr debridement vs combination diamond burr debridement and superficial grid keratotomy"],"prefix":"10.1111","volume":"21","author":[{"given":"Doris","family":"Wu","sequence":"first","affiliation":[{"name":"Department of Clinical Sciences College of Veterinary Medicine and Biomedical Sciences Colorado State University Fort Collins CO USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sara M.","family":"Smith","sequence":"additional","affiliation":[{"name":"University of Pennsylvania School of Veterinary Medicine Philadelphia PA USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jessica","family":"M. 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