{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,31]],"date-time":"2025-10-31T07:45:53Z","timestamp":1761896753156},"reference-count":37,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2018,2,26]],"date-time":"2018-02-26T00:00:00Z","timestamp":1519603200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Veterinary Ophthalmology"],"published-print":{"date-parts":[[2018,11]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>An approximately 2\u2010year\u2010old female Doberman Pinscher was referred for the evaluation of bilateral, chronic proliferative conjunctivitis. Ophthalmic examination revealed bilateral thick, opaque pseudomembranes originating from the conjunctivae that prevented visualization of the cornea and interior structures of the eye. Histopathological findings of biopsies of the pseudomembranes were consistent with ligneous conjunctivitis. Serum plasminogen activity levels were within the normal range. Treatment with topical and systemic anti\u2010inflammatory and immunosuppressive drugs did not improve the conjunctival lesions. The pseudomembranes were surgically excised, and the conjunctival surfaces were reconstructed with amniotic membrane. At final re\u2010examination two years postsurgery, there was no evidence of recurrence of the pseudomembranes. To the authors\u2019 knowledge, this is the first reported case of the successful treatment of canine ligneous conjunctivitis with amniotic membrane transplantation.<\/jats:p>","DOI":"10.1111\/vop.12559","type":"journal-article","created":{"date-parts":[[2018,2,26]],"date-time":"2018-02-26T23:22:42Z","timestamp":1519687362000},"page":"652-660","update-policy":"http:\/\/dx.doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":4,"title":["Amniotic membrane transplantation for ligneous conjunctivitis in a doberman"],"prefix":"10.1111","volume":"21","author":[{"given":"Louise","family":"O'Leary","sequence":"first","affiliation":[{"name":"Department of Small Animal Clinical Sciences University of Florida Gainesville FL USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Andrew","family":"Specht","sequence":"additional","affiliation":[{"name":"Department of Small Animal Clinical Sciences University of Florida Gainesville FL 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