{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2023,9,15]],"date-time":"2023-09-15T10:18:37Z","timestamp":1694773117448},"reference-count":10,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2018,9,13]],"date-time":"2018-09-13T00:00:00Z","timestamp":1536796800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Veterinary Ophthalmology"],"published-print":{"date-parts":[[2019,3]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Six dogs were diagnosed with punctal stenosis following the long\u2010term use of topical neomycin\u2010polymyxin B\u2010dexamethasone (<jats:styled-content style=\"fixed-case\">NPD<\/jats:styled-content>). All patients were initially presented for ophthalmic diseases requiring ongoing anti\u2010inflammatory therapy. Five of the 6 dogs had previously or concurrently been treated with topical anti\u2010inflammatory medications other than <jats:styled-content style=\"fixed-case\">NPD<\/jats:styled-content>. One patient exclusively received topical <jats:styled-content style=\"fixed-case\">NPD<\/jats:styled-content> prior to the diagnosis of punctal stenosis. The onset of punctal stenosis following therapy with <jats:styled-content style=\"fixed-case\">NPD<\/jats:styled-content> was variable among patients, ranging from 4\u00a0months to over 1\u00a0year. Diagnosis of punctal stenosis was made based upon the presence of epiphora and visualization of fibrotic tissue over the nasolacrimal puncta.<\/jats:p>","DOI":"10.1111\/vop.12610","type":"journal-article","created":{"date-parts":[[2018,9,13]],"date-time":"2018-09-13T11:58:44Z","timestamp":1536839924000},"page":"196-200","update-policy":"http:\/\/dx.doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["Punctal stenosis in 6 dogs following the long\u2010term use of topical neomycin\u2010polymyxin B\u2010dexamethasone"],"prefix":"10.1111","volume":"22","author":[{"given":"Katelin","family":"Quantz","sequence":"first","affiliation":[{"name":"Department of Veterinary Clinical Sciences College of Veterinary Medicine Purdue University West Lafayette Indiana"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jean","family":"Stiles","sequence":"additional","affiliation":[{"name":"Department of Veterinary Clinical Sciences College of Veterinary Medicine Purdue University West Lafayette Indiana"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2018,9,13]]},"reference":[{"key":"e_1_2_4_2_1","doi-asserted-by":"publisher","DOI":"10.2147\/OPTH.S31904"},{"key":"e_1_2_4_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0002-9394(03)00664-0"},{"key":"e_1_2_4_4_1","doi-asserted-by":"publisher","DOI":"10.1097\/IOP.0000000000000204"},{"key":"e_1_2_4_5_1","doi-asserted-by":"publisher","DOI":"10.1186\/1752-1947-2-57"},{"key":"e_1_2_4_6_1","first-page":"854","article-title":"Adverse external ocular effects of topical ophthalmic therapy: an epidemiologic, laboratory, and clinical study","volume":"81","author":"Wilson FM","year":"1983","journal-title":"Trans Am Ophthalmol Soc"},{"key":"e_1_2_4_7_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0953-4431(96)00192-0"},{"key":"e_1_2_4_8_1","doi-asserted-by":"publisher","DOI":"10.1159\/000217727"},{"key":"e_1_2_4_9_1","doi-asserted-by":"publisher","DOI":"10.1080\/01676830490916055"},{"key":"e_1_2_4_10_1","doi-asserted-by":"publisher","DOI":"10.3109\/01676830.2015.1014513"},{"key":"e_1_2_4_11_1","doi-asserted-by":"publisher","DOI":"10.1038\/eye.2014.342"}],"container-title":["Veterinary Ophthalmology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fvop.12610","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/vop.12610","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,9,14]],"date-time":"2023-09-14T19:20:17Z","timestamp":1694719217000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/vop.12610"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2018,9,13]]},"references-count":10,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2019,3]]}},"alternative-id":["10.1111\/vop.12610"],"URL":"https:\/\/doi.org\/10.1111\/vop.12610","archive":["Portico"],"relation":{},"ISSN":["1463-5216","1463-5224"],"issn-type":[{"value":"1463-5216","type":"print"},{"value":"1463-5224","type":"electronic"}],"subject":[],"published":{"date-parts":[[2018,9,13]]},"assertion":[{"value":"2018-01-05","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2018-07-17","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2018-09-13","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}