{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,27]],"date-time":"2026-10-27T07:03:33Z","timestamp":1793084613879,"version":"4.5.0"},"reference-count":44,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2019,8,29]],"date-time":"2019-08-29T00:00:00Z","timestamp":1567036800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Veterinary Ophthalmology"],"published-print":{"date-parts":[[2020,1]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Objective<\/jats:title>\n                    <jats:p>To describe ocular surface complications following micropulse transscleral cyclophotocoagulation (MP\u2010TSCPC) in dogs.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Animals studied<\/jats:title>\n                    <jats:p>Eighteen dogs treated with MP\u2010TSCPC at two institutions for glaucoma management.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Procedures<\/jats:title>\n                    <jats:p>MP\u2010TSCPC was applied to each eye (avoiding 3 and 9 o'clock positions) with 31.3% duty cycle, 2000\u20103000\u00a0mW energy, and 90\u2010180\u00a0seconds duration per hemisphere. Central corneal tactile sensation (CTS) and Schirmer tear test\u20101 (STT\u20101) were measured at baseline and \u22652 post\u2010operative visits in each dog.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>Corneal sensitivity decreased in 16\/18 dogs (89%) by an average of 10%\u201042% (up to 100% in 4 dogs). CTS decline was rapid (\u22641\u00a0week) and only fully recovered in 50% of dogs within 8\u2010180\u00a0days. Patients' age, glaucoma duration, laser energy, and total energy delivered did not affect CTS at any visit. However, brachycephalic dogs had significantly lower CTS and likelihood to recover full sensation compared with nonbrachycephalic dogs. Aqueous tear deficiency (STT\u20101\u00a0&lt;\u00a015\u00a0mm\/min) occurred in 8\/18 dogs (44%) within 7\u2010270\u00a0days, and concurrent signs of keratoconjunctivitis sicca were noted in 2\/18 dogs (11%). Neurotrophic corneal ulcers developed in 6\/18 dogs (33.3%) and required 16\u201053\u00a0days to heal.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>Corneal hypoesthesia is a common complication of MP\u2010TSCPC in dogs, and can lead to serious adverse effects such as aqueous tear deficiency and neurotrophic corneal ulcers. Brachycephalic dogs represent a population at higher risk. Close monitoring of ocular surface health is recommended for months following MP\u2010TSCPC in dogs.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/vop.12705","type":"journal-article","created":{"date-parts":[[2019,8,29]],"date-time":"2019-08-29T05:42:40Z","timestamp":1567057360000},"page":"171-180","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":28,"title":["Corneal hypoesthesia, aqueous tear deficiency, and neurotrophic keratopathy following micropulse transscleral cyclophotocoagulation in dogs"],"prefix":"10.1111","volume":"23","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-0103-0127","authenticated-orcid":false,"given":"Lionel","family":"Sebbag","sequence":"first","affiliation":[{"name":"Department of Veterinary Clinical Sciences Iowa State University, College of Veterinary Medicine Ames Iowa"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Elizabeth 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