{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,29]],"date-time":"2026-05-29T11:13:10Z","timestamp":1780053190500,"version":"3.54.0"},"reference-count":17,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2019,12,4]],"date-time":"2019-12-04T00:00:00Z","timestamp":1575417600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"name":"Comparative Ophthalmic Research Laboratories"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Veterinary Ophthalmology"],"published-print":{"date-parts":[[2020,3]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Objective<\/jats:title><jats:p>The purpose of this study was to compare the leakage rates of perilimbal uniplanar and biplanar clear corneal incisions in dogs when subjected to increased intraocular pressure (IOP) both from within the eye and via external pressure.<\/jats:p><\/jats:sec><jats:sec><jats:title>Procedure<\/jats:title><jats:p>Uniplanar clear corneal incisions were created in eight freshly enucleated canine eyes using a 3.2\u00a0mm straight slit knife while 8 fellow eyes received a biplanar clear corneal incision consisting of an approximately 300\u00a0\u03bcm deep groove followed by a 3.2\u00a0mm straight slit knife entry into the anterior chamber. Both wounds were reapposed using three simple interrupted 8\u20100 polyglactin 910 sutures. Eyes were cannulated with two 25\u00a0g needles: One connected to a pressure transducer, and the other connected to a reservoir of isotonic saline. The IOP at which the wound leaked was recorded when the intraocular pressure was increased internally by raising the height of the fluid bag, and again when the cornea was externally compressed. Kaplan\u2010Meier survival curves compared incision types for each method of increasing IOP and were evaluated using Mantel\u2010Cox log\u2010rank analysis.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Both wound types resisted leakage at IOP in the physiologically achievable range and no significant differences were observed between clear corneal incisions when pressure was applied externally (<jats:italic>P<\/jats:italic>\u00a0=\u00a0.353) or was increased from within the globe (<jats:italic>P<\/jats:italic>\u00a0=\u00a0.615).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>Ex vivo uniplanar and biplanar clear corneal incisions in dogs are equally strong, with no significant differences in leakage rates when IOP is increased internally or externally.<\/jats:p><\/jats:sec>","DOI":"10.1111\/vop.12729","type":"journal-article","created":{"date-parts":[[2019,12,4]],"date-time":"2019-12-04T12:06:45Z","timestamp":1575461205000},"page":"325-330","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Wound leakage rates of ex vivo uniplanar versus biplanar phacoemulsification clear corneal incisions in dogs"],"prefix":"10.1111","volume":"23","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-6395-2178","authenticated-orcid":false,"given":"Kevin","family":"Snyder","sequence":"first","affiliation":[{"name":"School of Veterinary Medicine University of Wisconsin\u2010Madison Madison WI USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hannah","family":"Terhaar","sequence":"additional","affiliation":[{"name":"School of Veterinary Medicine University of Wisconsin\u2010Madison Madison WI USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7553-3942","authenticated-orcid":false,"given":"Ellison","family":"Bentley","sequence":"additional","affiliation":[{"name":"School of Veterinary Medicine University of Wisconsin\u2010Madison Madison WI USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Paul E.","family":"Miller","sequence":"additional","affiliation":[{"name":"School of Veterinary Medicine University of Wisconsin\u2010Madison Madison WI USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2019,12,4]]},"reference":[{"key":"e_1_2_6_2_1","first-page":"718","volume-title":"Veterinary Ophthalmology","author":"Wilkie D","year":"2015"},{"key":"e_1_2_6_3_1","first-page":"180","volume-title":"Atlas of Veterinary Ophthalmic Surgery","author":"Bistner SI","year":"1977"},{"key":"e_1_2_6_4_1","first-page":"921","article-title":"Cataract surgery and methods of 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