{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,22]],"date-time":"2026-10-22T17:04:06Z","timestamp":1792688646237,"version":"4.5.0"},"reference-count":38,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2020,8,13]],"date-time":"2020-08-13T00:00:00Z","timestamp":1597276800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Veterinary Ophthalmology"],"published-print":{"date-parts":[[2020,9]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Objective<\/jats:title><jats:p>To document a case series using corneoconjunctival transposition (CCT) surgery with and without bioscaffolding matrix (ACell<jats:sup>\u00ae<\/jats:sup>) to repair deep corneal ulcers and perforations in dogs.<\/jats:p><\/jats:sec><jats:sec><jats:title>Animals studied<\/jats:title><jats:p>Eighteen dogs of various breeds that presented with deep or perforating corneal ulcers.<\/jats:p><\/jats:sec><jats:sec><jats:title>Procedures<\/jats:title><jats:p>Corneoconjunctival transposition grafts with or without ACell<jats:sup>\u00ae<\/jats:sup>were sutured using a simple interrupted 8\u20100 or 9\u20100 polyglactin 910 pattern.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>A total of eighteen dogs (19 eyes) were diagnosed with deep corneal ulcers (n\u00a0=\u00a07) and perforating corneal ulcers (n\u00a0=\u00a012). A CCT was performed in all eyes, with ten of them additionally receiving an ACell<jats:sup>\u00ae<\/jats:sup>graft. The majority of lesions were located axially in 14\/19 (81%) eyes. Grafts were harvested from dorsal (n\u00a0=\u00a08), temporal (n\u00a0=\u00a05), ventral (n\u00a0=\u00a04), or nasal (n\u00a0=\u00a02) quadrants. Brachycephalic breeds (13\/18) were over\u2010represented. Keratoconjunctivitis sicca was present in 10\/19 eyes (52.6%). Bacterial isolates were cultured from 8\/19 eyes. Post\u2010operative therapy included topical antibiotics, plasma, cycloplegics, oral antibiotics, and oral nonsteroidal anti\u2010inflammatory drugs. CCT integration with and without ACell<jats:sup>\u00ae<\/jats:sup>occurred at a median of 20\u00a0days (range 7\u201038\u00a0days) post\u2010operatively with no significant difference between groups. Median follow\u2010up time was 188\u00a0days.\u00a0Short\u2010term post\u2010operative complications included granulation tissue formation (19\/19), corneal edema (4\/19), graft retraction (4\/19), and anterior synechia (1\/19). Long\u2010term complications in 14 eyes with follow\u2010up &gt;30\u00a0days included superficial corneal pigmentation (6\/14) and epithelial inclusion cysts (5\/14). Two eyes were nonvisual at last follow\u2010up due to cataract formation.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>Corneoconjunctival transposition with ACell<jats:sup>\u00ae<\/jats:sup>can be utilized for corneal ulcer repair in dogs.<\/jats:p><\/jats:sec>","DOI":"10.1111\/vop.12815","type":"journal-article","created":{"date-parts":[[2020,8,13]],"date-time":"2020-08-13T12:24:34Z","timestamp":1597321474000},"page":"884-891","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":13,"title":["Corneoconjunctival transposition with and without ACell<sup>\u00ae<\/sup>for deep corneal ulcer repair in 18 dogs"],"prefix":"10.1111","volume":"23","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-8993-180X","authenticated-orcid":false,"given":"Alessandra V.","family":"Keenan","sequence":"first","affiliation":[{"name":"Department of Veterinary Clinical Sciences College of Veterinary Medicine Auburn University 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