{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,28]],"date-time":"2026-01-28T14:25:26Z","timestamp":1769610326892,"version":"3.49.0"},"reference-count":46,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2020,12,2]],"date-time":"2020-12-02T00:00:00Z","timestamp":1606867200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Veterinary Ophthalmology"],"published-print":{"date-parts":[[2021,1]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Objective<\/jats:title><jats:p>To evaluate changes in intraocular pressure (IOP) with variable head position in healthy, anesthetized horses in hoisted inversion and to assess the influence of various cofactors (age, sex, body weight, body condition score, and neck length) on IOP changes during hoisting.<\/jats:p><\/jats:sec><jats:sec><jats:title>Animals studied<\/jats:title><jats:p>Seventeen healthy adult horses without significant ocular abnormalities.<\/jats:p><\/jats:sec><jats:sec><jats:title>Procedures<\/jats:title><jats:p>Subjects were administered intravenous xylazine\/butorphanol premedication and ketamine\/midazolam induction with xylazine\/ketamine boluses for anesthetic maintenance. While hoisted, IOP was measured in triplicate for each eye via rebound tonometry (TonoVet) at neutral head position (ie, eyes level with the withers), at multiple 5\u00a0cm increments above and below neutral (\u221220\u00a0cm through +20\u00a0cm) using foam pads for head support, and with eyes above heart level via manual support.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>In hoisted positions, IOP ranged from 18 to 51\u00a0mmHg. Intraocular pressure significantly decreased with head position elevated \u2265+15\u00a0cm from neutral and significantly increased when lowered \u2264\u22125\u00a0cm from neutral. Neck length significantly influenced IOP (<jats:italic>P<\/jats:italic>\u00a0=\u00a0.0328) with linear regression indicating a median (range) increase of 0.244 (0.034\u20100.425) mmHg in IOP for every 1\u00a0cm increase in neck length. Age, sex, breed, body weight, body condition score, and eye (OD vs OS) did not significantly influence IOP. Intraocular pressure only varied significantly between eyes at +10\u00a0cm above neutral (OS\u00a0&gt;\u00a0OD, 1.7\u00a0\u00b1\u00a00.6\u00a0mm\u00a0Hg,<jats:italic>P<\/jats:italic>\u00a0=\u00a0.0044).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>Intraocular pressure in healthy, anesthetized horses varies with head position during hoisting; increased neck length may be associated with larger changes in IOP during hoisting.<\/jats:p><\/jats:sec>","DOI":"10.1111\/vop.12849","type":"journal-article","created":{"date-parts":[[2020,12,2]],"date-time":"2020-12-02T22:10:29Z","timestamp":1606947029000},"page":"71-79","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":6,"title":["Effect of multiple head positions on intraocular pressure in healthy, anesthetized horses during 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