{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,12]],"date-time":"2026-03-12T09:03:25Z","timestamp":1773306205320,"version":"3.50.1"},"reference-count":18,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2021,2,5]],"date-time":"2021-02-05T00:00:00Z","timestamp":1612483200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Veterinary Ophthalmology"],"published-print":{"date-parts":[[2021,3]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>This report describes the clinical features, histopathology, and surgical treatment of a case of conjunctival calcification in a 5\u2010month\u2010old female English Setter, referred with a history of recurrent conjunctivitis in the right eye (OD). The ophthalmic findings were limited to multifocal white plaques embedded in a markedly inflamed conjunctiva of the eyelids and the anterior nictitating membrane OD. Calcification was suspected. The blood cell count, blood chemical profile, and urinalysis were within normal limits, and long\u2010bone radiographs appeared normal. After removal of the affected area by means of a large conjunctivectomy, cryopreserved canine amniotic membrane (AM) was transplanted to fill in the defect. Multifocal ectopic calcium deposits in the conjunctival <jats:italic>lamina propria<\/jats:italic> were confirmed histopathologically. The postoperative healing was uneventful, and no recurrence was observed during a follow\u2010up period of five years. Conjunctival mineralization is uncommon in canine ophthalmology, and the cause remained undetermined in the present case, for which AM transplantation was able to promote conjunctival healing after a large surgical excision.<\/jats:p>","DOI":"10.1111\/vop.12864","type":"journal-article","created":{"date-parts":[[2021,2,8]],"date-time":"2021-02-08T06:26:07Z","timestamp":1612765567000},"page":"203-208","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["Conjunctival <i>calcinosis circumscripta<\/i> in a dog: Treatment combining surgical resection and amniotic membrane grafting"],"prefix":"10.1111","volume":"24","author":[{"given":"Marie\u2010Claire","family":"Robin","sequence":"first","affiliation":[{"name":"Small Animal Clinic Universit\u00e9 de Toulouse ENVT Toulouse France"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sebastien","family":"Raffestin","sequence":"additional","affiliation":[{"name":"Clinique V\u00e9t\u00e9rinaire Olonzac France"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Claire Lyse","family":"Etienne","sequence":"additional","affiliation":[{"name":"LabHPEC\u2010ENVT and STROMALab CNRS ERL5311, EFS, ENVT, Inserm U1031, UPS Universit\u00e9 de Toulouse Toulouse France"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8723-5472","authenticated-orcid":false,"given":"Isabelle","family":"Raymond Letron","sequence":"additional","affiliation":[{"name":"Small Animal Clinic Universit\u00e9 de Toulouse ENVT Toulouse France"},{"name":"LabHPEC\u2010ENVT and STROMALab CNRS ERL5311, EFS, ENVT, Inserm U1031, UPS Universit\u00e9 de Toulouse Toulouse France"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5535-7435","authenticated-orcid":false,"given":"Alain","family":"Regnier","sequence":"additional","affiliation":[{"name":"Small Animal Clinic Universit\u00e9 de Toulouse ENVT Toulouse France"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0426-4957","authenticated-orcid":false,"given":"Jean Yves","family":"Douet","sequence":"additional","affiliation":[{"name":"Small Animal Clinic Universit\u00e9 de Toulouse ENVT Toulouse France"},{"name":"IHAP INRAE, ENVT Universit\u00e9 de Toulouse Toulouse France"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2021,2,5]]},"reference":[{"key":"e_1_2_6_2_1","doi-asserted-by":"publisher","DOI":"10.1001\/jama.250.1.78"},{"key":"e_1_2_6_3_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1439-0442.2004.00675.x"},{"key":"e_1_2_6_4_1","doi-asserted-by":"publisher","DOI":"10.1111\/hdi.12236"},{"key":"e_1_2_6_5_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-3164.1997.tb00260.x"},{"key":"e_1_2_6_6_1","doi-asserted-by":"publisher","DOI":"10.1136\/bjo.63.3.177"},{"key":"e_1_2_6_7_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1751-0813.2001.tb14575.x"},{"key":"e_1_2_6_8_1","first-page":"34","article-title":"Drug\u2010induced conjunctival calcification in a dog","volume":"17","author":"Bryan GM","year":"1992","journal-title":"Canine Pract"},{"key":"e_1_2_6_9_1","doi-asserted-by":"crossref","unstructured":"GelattKN GelattJP.Veterinary Ophthalmic Surgery Elsevier Health Sciences UK.2011.","DOI":"10.1016\/B978-0-7020-3429-9.00003-1"},{"key":"e_1_2_6_10_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10561-017-9618-5"},{"key":"e_1_2_6_11_1","doi-asserted-by":"publisher","DOI":"10.1046\/j.1463-5224.1998.00026.x"},{"key":"e_1_2_6_12_1","doi-asserted-by":"publisher","DOI":"10.1111\/vop.12559"},{"key":"e_1_2_6_13_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.survophthal.2009.03.004"},{"key":"e_1_2_6_14_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.2042-3292.2010.00214.x"},{"key":"e_1_2_6_15_1","doi-asserted-by":"publisher","DOI":"10.1354\/vp.44-2-222"},{"key":"e_1_2_6_16_1","doi-asserted-by":"publisher","DOI":"10.1097\/00003226-198706020-00002"},{"key":"e_1_2_6_17_1","unstructured":"2019 Histologic Basis of Ocular Disease in Animals Hoboken new Jersey B Grahn R Peiffer BP Wilcock B Grahn R Peiffer BP Wilcock Histopathology of ocular trauma 89 104"},{"key":"e_1_2_6_18_1","doi-asserted-by":"publisher","DOI":"10.1016\/B978-0-7020-2983-7.00054-1"},{"key":"e_1_2_6_19_1","doi-asserted-by":"publisher","DOI":"10.1001\/archopht.117.10.1414"}],"container-title":["Veterinary Ophthalmology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/vop.12864","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1111\/vop.12864","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/vop.12864","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,9,1]],"date-time":"2023-09-01T13:13:40Z","timestamp":1693574020000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/vop.12864"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,2,5]]},"references-count":18,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2021,3]]}},"alternative-id":["10.1111\/vop.12864"],"URL":"https:\/\/doi.org\/10.1111\/vop.12864","archive":["Portico"],"relation":{},"ISSN":["1463-5216","1463-5224"],"issn-type":[{"value":"1463-5216","type":"print"},{"value":"1463-5224","type":"electronic"}],"subject":[],"published":{"date-parts":[[2021,2,5]]},"assertion":[{"value":"2020-04-30","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2021-01-16","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2021-02-05","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}