{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,26]],"date-time":"2026-09-26T20:08:09Z","timestamp":1790453289855,"version":"4.1.0"},"reference-count":39,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2021,2,19]],"date-time":"2021-02-19T00:00:00Z","timestamp":1613692800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Veterinary Ophthalmology"],"published-print":{"date-parts":[[2021,3]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Introduction<\/jats:title><jats:p>Classically, sporotrichosis occurs as a chronic granulomatous lymphocutaneous infection. The extracutaneous form is uncommon and may affect the eye without cutaneous involvement. The most frequent form of ocular sporotrichosis reported in humans is a granulomatous conjunctivitis. There are no previous reports on primary ocular sporotrichosis in cats.<\/jats:p><\/jats:sec><jats:sec><jats:title>Procedures<\/jats:title><jats:p>Three mixed breed cats rescued from shelters were referred by the veterinarian for ophthalmic evaluation with a complaint of conjunctivitis nonresponsive to treatment with no evidence of skin disease or systemic disease. Complete ophthalmic examination, conjunctival cytology, and microbiological analysis were performed.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Ophthalmic examinations revealed epiphora, purulent ocular discharge, conjunctival hyperemia, and a mass in the palpebral conjunctiva. Conjunctival cytology revealed segmented and degenerated neutrophils, conjunctival epithelial cells, and an abundant number of round and oval cells compatible with <jats:italic>Sporothrix<\/jats:italic> spp. Microbiological culture was performed and confirmed the presence of fungi from the <jats:italic>Sporothrix schenckii<\/jats:italic> complex. All animals were treated with oral itraconazole; two animals received topical itraconazole in association with oral treatment. Case 1 was refractory to treatment, and iodate potassium was combined with itraconazole therapy without resolution at the time of this publication. Cases 2 and 3 had complete resolution of conjunctival lesions with four months of oral and topical itraconazole therapy.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>Conjunctival sporotrichosis should be considered as a differential diagnosis of conjunctivitis in cats from endemic regions. Conjunctival cytology is an important tool that can aid early diagnosis.<\/jats:p><\/jats:sec>","DOI":"10.1111\/vop.12865","type":"journal-article","created":{"date-parts":[[2021,2,21]],"date-time":"2021-02-21T03:02:54Z","timestamp":1613876574000},"page":"209-215","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":11,"title":["Primary conjunctival sporotrichosis in three cats from Northeastern Brazil"],"prefix":"10.1111","volume":"24","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-8372-0801","authenticated-orcid":false,"given":"Taciana P.","family":"Spinelli","sequence":"first","affiliation":[{"name":"Departamento de Medicina Veterin\u00e1ria Universidade Federal Rural de Pernambuco Recife Brasil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Leticia M.","family":"Bezerra","sequence":"additional","affiliation":[{"name":"Departamento de Medicina Veterin\u00e1ria Universidade Federal Rural de Pernambuco Recife Brasil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bruno O.F.","family":"de Souza","sequence":"additional","affiliation":[{"name":"School of Optometry University of Montreal Quebec Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Angelica","family":"Rocha","sequence":"additional","affiliation":[{"name":"Departamento de Medicina Veterin\u00e1ria Universidade Federal Rural de Pernambuco Recife Brasil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Joaquim E.","family":"Neto","sequence":"additional","affiliation":[{"name":"Departamento de Morfologia e Fisiologia Animal Universidade Federal Rural de Pernambuco Brasil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fabr\u00edcio B.","family":"S\u00e1","sequence":"additional","affiliation":[{"name":"Departamento de Morfologia e Fisiologia Animal Universidade Federal Rural de Pernambuco Brasil"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2021,2,19]]},"reference":[{"key":"e_1_2_6_2_1","doi-asserted-by":"publisher","DOI":"10.1093\/mmy\/myu062"},{"key":"e_1_2_6_3_1","doi-asserted-by":"publisher","DOI":"10.3390\/jof4030095"},{"issue":"2","key":"e_1_2_6_4_1","doi-asserted-by":"crossref","first-page":"113","DOI":"10.1007\/BF00436061","article-title":"Epidemiology of sporotrichosis in Latin America","volume":"108","author":"Conti D\u00edaz IA","year":"1989","journal-title":"Mycopathologia"},{"key":"e_1_2_6_5_1","doi-asserted-by":"publisher","DOI":"10.1001\/jama.1978.03290030050018"},{"key":"e_1_2_6_6_1","doi-asserted-by":"publisher","DOI":"10.1007\/978-3-319-72093-7_10"},{"key":"e_1_2_6_7_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.ppat.1006077"},{"key":"e_1_2_6_8_1","doi-asserted-by":"publisher","DOI":"10.1093\/mmy\/myz024"},{"issue":"17","key":"e_1_2_6_9_1","first-page":"2147","article-title":"Sporotrichosis; etiologic considerations and report of additional cases from New York","volume":"52","author":"Singer JI","year":"1952","journal-title":"N Y State J Med"},{"key":"e_1_2_6_10_1","doi-asserted-by":"publisher","DOI":"10.1001\/archderm.1982.01650180063020"},{"issue":"6","key":"e_1_2_6_11_1","first-page":"2","article-title":"Feline\u2010transmitted Sporotrichosis: A case study from California","volume":"17","author":"Rees RK","year":"2011","journal-title":"Dermatol Online J"},{"key":"e_1_2_6_12_1","doi-asserted-by":"publisher","DOI":"10.1093\/clind\/16.3.384"},{"issue":"1","key":"e_1_2_6_13_1","first-page":"33","article-title":"Esporotricosis transmitida por gato dom\u00e9stico. 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