{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,26]],"date-time":"2026-06-26T08:53:30Z","timestamp":1782464010740,"version":"3.54.5"},"reference-count":23,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2021,2,16]],"date-time":"2021-02-16T00:00:00Z","timestamp":1613433600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Veterinary Ophthalmology"],"published-print":{"date-parts":[[2021,5]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Objective<\/jats:title><jats:p>To describe the surgical repair of traumatic complete spectaculectomy and keratomalacia in a snake.<\/jats:p><\/jats:sec><jats:sec><jats:title>Animals<\/jats:title><jats:p>A 10.5\u2010year\u2010old, female, Boelen's python (<jats:italic>Simalia boeleni<\/jats:italic>) was presented with iatrogenic, near\u2010complete spectaculectomy associated with bacterial keratitis, keratomalacia, and hypopyon.<\/jats:p><\/jats:sec><jats:sec><jats:title>Procedures<\/jats:title><jats:p>Corneal samples for cytological evaluation and bacterial culture were collected. Following medical stabilization of the bacterial keratitis, a double\u2010layered dry amniotic membrane graft was placed. The first amniotic membrane layer was placed over the cornea with the edges tucked under the peripheral remnants of the spectacle and secured in place with fibrin glue. The second amniotic membrane layer was placed over the entirety of the spectacle remnant and secured in place with a combination of fibrin glue and sutures. Topical and systemic antimicrobials, topical ophthalmic lubricants, and systemic non\u2010steroidal anti\u2010inflammatory therapy were administered postoperatively.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Heterophilic keratitis was identified by cytology and <jats:italic>Enterobacter cloacae<\/jats:italic>, <jats:italic>Pseudomonas aeruginosa<\/jats:italic>, and <jats:italic>Staphylococcus sciuri<\/jats:italic> were cultured from the corneal samples. The amniotic membrane grafts remained in place for several weeks. At 4\u00a0months postoperatively, the spectacle was completely regenerated, the subspectacular space restored, and the cornea was transparent. Spectacular vascularization and fibrosis then slowly cleared over the following 6\u00a0months.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions and clinical relevance<\/jats:title><jats:p>Amniotic membrane grafting with fibrin glue is a relatively simple and effective surgical method to reconstruct extensive defects in the reptilian spectacle and to assist in the management of bacterial keratitis associated with spectacle avulsion.<\/jats:p><\/jats:sec>","DOI":"10.1111\/vop.12869","type":"journal-article","created":{"date-parts":[[2021,2,19]],"date-time":"2021-02-19T06:25:03Z","timestamp":1613715903000},"page":"295-300","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["Amniotic membrane grafting for traumatic complete spectaculectomy and keratomalacia in a Boelen\u2019s python (<i>Simalia<\/i><i>boeleni<\/i>)"],"prefix":"10.1111","volume":"24","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-1894-8839","authenticated-orcid":false,"given":"Eric C.","family":"Ledbetter","sequence":"first","affiliation":[{"name":"From the Department of Clinical Sciences College of Veterinary Medicine Cornell University Ithaca NY USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jonah S.","family":"Marion","sequence":"additional","affiliation":[{"name":"From the Department of Clinical Sciences College of Veterinary Medicine Cornell University Ithaca NY USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"James K.","family":"Morrisey","sequence":"additional","affiliation":[{"name":"From the Department of Clinical Sciences College of Veterinary Medicine Cornell University Ithaca NY USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2021,2,16]]},"reference":[{"key":"e_1_2_5_2_1","doi-asserted-by":"publisher","DOI":"10.1111\/vop.12281"},{"key":"e_1_2_5_3_1","doi-asserted-by":"publisher","DOI":"10.1002\/jmor.21094"},{"key":"e_1_2_5_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/0042-6989(77)90093-1"},{"key":"e_1_2_5_5_1","doi-asserted-by":"publisher","DOI":"10.1186\/s12917-017-1193-2"},{"key":"e_1_2_5_6_1","doi-asserted-by":"publisher","DOI":"10.1002\/jmor.20262"},{"key":"e_1_2_5_7_1","doi-asserted-by":"publisher","DOI":"10.1111\/vop.12184"},{"key":"e_1_2_5_8_1","first-page":"109","article-title":"Ocular surface disease in reptiles","volume":"22","author":"Smith Fleming KM","year":"2019","journal-title":"Vet Clin N Am"},{"key":"e_1_2_5_9_1","first-page":"357","article-title":"Diseases of the organs and special senses","author":"Rosenwax A","year":"2018","journal-title":"Reptile Med Surg Clin Pract"},{"key":"e_1_2_5_10_1","doi-asserted-by":"publisher","DOI":"10.1016\/B978-0-323-48253-0.00091-X"},{"key":"e_1_2_5_11_1","doi-asserted-by":"publisher","DOI":"10.2460\/javma.243.2.252"},{"key":"e_1_2_5_12_1","doi-asserted-by":"publisher","DOI":"10.1111\/vop.12174"},{"key":"e_1_2_5_13_1","doi-asserted-by":"publisher","DOI":"10.1177\/0300985815588605"},{"key":"e_1_2_5_14_1","doi-asserted-by":"publisher","DOI":"10.5818\/1529-9651-20.1.29"},{"key":"e_1_2_5_15_1","doi-asserted-by":"crossref","first-page":"159","DOI":"10.1002\/9781118709627.ch10","volume-title":"The reptile eye. 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