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The most common pure bacterial isolate was\n                      <jats:italic>Pseudomonas aeruginosa<\/jats:italic>\n                      (\n                      <jats:italic>n<\/jats:italic>\n                      \u00a0=\u00a026) followed by \u03b2\u2010hemolytic\n                      <jats:italic>Streptococcus<\/jats:italic>\n                      (\n                      <jats:italic>n<\/jats:italic>\n                      \u00a0=\u00a012). Melting corneal ulcers that cultured coagulase\u2010positive\n                      <jats:italic>Staphylococcus<\/jats:italic>\n                      , coliform bacteria,\n                      <jats:italic>Pasteurella multocida<\/jats:italic>\n                      ,\n                      <jats:italic>Enterococcus<\/jats:italic>\n                      , and\n                      <jats:italic>Streptococcus viridans<\/jats:italic>\n                      presented in smaller numbers and were analyzed together (\n                      <jats:italic>n<\/jats:italic>\n                      \u00a0=\u00a016). Multiple cultures were identified in nine cases (\n                      <jats:italic>n<\/jats:italic>\n                      \u00a0=\u00a09\n                      <jats:italic>)<\/jats:italic>\n                      . Forty\u2010seven cultures yielded no bacterial growth (\n                      <jats:italic>n<\/jats:italic>\n                      \u00a0=\u00a047). The susceptibility to fluoroquinolones remained high with the exception of\n                      <jats:italic>\u03b2<\/jats:italic>\n                      \u2010hemolytic\n                      <jats:italic>Streptococci<\/jats:italic>\n                      . There was no significant difference in the ulcer severity at presentation in regard to the cultured bacteria. Overall, 63 eyes (57%) received surgical grafting in addition to medical treatment. In 14 cases (13%), the progression of corneal melting despite medical \u00b1 surgical treatment resulted in enucleation. Fifty\u2010seven percent (8\/14) of the enucleated eyes cultured pure\n                      <jats:italic>Pseudomonas aeruginosa<\/jats:italic>\n                      isolates. In contrast, all \u03b2\u2010hemolytic\n                      <jats:italic>Streptococcus<\/jats:italic>\n                      \u2010associated ulcers healed.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>\n                      The most common bacterial species associated with canine keratomalacia were\n                      <jats:italic>Pseudomonas aeruginosa<\/jats:italic>\n                      and \u03b2\u2010hemolytic\n                      <jats:italic>Streptococcus<\/jats:italic>\n                      . Because of the variation in antibacterial sensitivity between these two species, bacterial culture and sensitivity testing should be performed in all dogs presenting with keratomalacia. Melting corneal ulcers associated with pure\n                      <jats:italic>Pseudomonas<\/jats:italic>\n                      infection were significantly more likely to result in globe loss than melting corneal ulcers associated with other cultures.\n                    <\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/vop.12885","type":"journal-article","created":{"date-parts":[[2021,4,1]],"date-time":"2021-04-01T14:33:48Z","timestamp":1617287628000},"page":"265-278","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":42,"title":["Melting corneal ulcers (keratomalacia) in dogs: A 5\u2010year clinical and microbiological study (2014\u20132018)"],"prefix":"10.1111","volume":"24","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-2773-5301","authenticated-orcid":false,"given":"Agata","family":"Tsvetanova","sequence":"first","affiliation":[{"name":"Davies Veterinary Specialists Manor Farm Business Park Hertfordshire 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