{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,6]],"date-time":"2026-05-06T17:13:12Z","timestamp":1778087592544,"version":"3.51.4"},"reference-count":29,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2021,8,17]],"date-time":"2021-08-17T00:00:00Z","timestamp":1629158400000},"content-version":"vor","delay-in-days":47,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Veterinary Ophthalmology"],"published-print":{"date-parts":[[2021,7]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Objective<\/jats:title><jats:p>Transplantation of minor salivary glands (MSGs) to the conjunctiva is a treatment option for patients suffering from dry eye disease. As there is not enough information about labial and buccal MSGs in dogs, the aim of this study was to provide evidence of the presence of these glands and to investigate their spatial arrangement and excretory ducts.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>The oral mucosa of the lower lip of 4 dogs and the whole lower jaw of 1 dog were used for histological and microCT analysis. Presence, number, volumes and the tissue depth of MSGs were assessed.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Histological analysis showed that compact tubulo\u2010acinar glands were located in the submucosal connective tissue. MicroCT images revealed that 9 to 21\u00a0MSGs were arranged in a single row at the level of the dental alveolae. The volume of the MSGs increased from rostral to caudal and the total volume of glandular tissue per animal ranged from 35.01\u00a0mm<jats:sup>3<\/jats:sup> to 549.43\u00a0mm<jats:sup>3<\/jats:sup>. The mean tissue depth of MSGs ranged from 0.57\u00a0mm to 1.37\u00a0mm (upper surface of glands) and between 1.43\u00a0mm and 3.09\u00a0mm (lower surface of the glands). Excretory ducts left the dorsal part of the glands and ran in dorso\u2010rostral direction.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>The location, number and volume of the labial and buccal MSGs in the dog could be detected and described using microCT scans and histology. The present results can provide valuable information for future transplantation of labial MSGs as therapeutic measure against keratoconjunctivitis sicca.<\/jats:p><\/jats:sec>","DOI":"10.1111\/vop.12920","type":"journal-article","created":{"date-parts":[[2021,8,17]],"date-time":"2021-08-17T12:25:32Z","timestamp":1629203132000},"page":"400-407","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":10,"title":["Labial and buccal minor salivary glands of the dog \u2013 location, three\u2010dimensional arrangement and histology"],"prefix":"10.1111","volume":"24","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-8853-5939","authenticated-orcid":false,"given":"Simone","family":"Gabner","sequence":"first","affiliation":[{"name":"Histology and Embryology Department of Pathobiology University of Veterinary Medicine Vienna Austria"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Christina","family":"Michels","sequence":"additional","affiliation":[{"name":"Histology and Embryology Department of Pathobiology University of Veterinary Medicine Vienna Austria"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Bernadette","family":"Lanz","sequence":"additional","affiliation":[{"name":"Histology and Embryology Department of Pathobiology University of Veterinary Medicine Vienna Austria"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Barbara","family":"Nell","sequence":"additional","affiliation":[{"name":"Department of Companion Animals and Horses University of Veterinary Medicine Vienna Austria"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Stephan","family":"Handschuh","sequence":"additional","affiliation":[{"name":"VetCore Facility for Research University of Veterinary Medicine Vienna Austria"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Monika","family":"Egerbacher","sequence":"additional","affiliation":[{"name":"UMIT TIROL Private University for Health Sciences Medical Informatics and Technology GmbH Hall in Tirol Austria"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2021,8,17]]},"reference":[{"issue":"9","key":"e_1_2_7_2_1","first-page":"1566","article-title":"Keratoconjunctivitis sicca in dogs","volume":"158","author":"Aguirre GD","year":"1971","journal-title":"J Am Vet Med Assoc"},{"key":"e_1_2_7_3_1","doi-asserted-by":"publisher","DOI":"10.1136\/vr.141.21.539"},{"key":"e_1_2_7_4_1","unstructured":"GrauwelsMFM.A study of keratoconjunctivitis sicca in the dog [M.V.M. 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