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To attempt delineation of a fovea\u2010like region in canine and feline SD\u2010OCT scans, aided by the identification of outer retinal thickness differences between retinal regions.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Spectralis\u00ae HRA\u2009+\u2009OCT SD\u2010OCT scans from healthy, anesthetized dogs (<jats:italic>n<\/jats:italic>\u00a0=\u00a010) and cats (<jats:italic>n<\/jats:italic>\u00a0=\u00a012) were analyzed. Scanlines on which the CC was identifiable were counted and CC visibility was scored. Outer nuclear layer (ONL) thickness and the distances from external limiting membrane (ELM) to retinal pigment epithelium\/Bruch's membrane complex (RPE\/BM) and ELM to CC were measured in the area centralis (AC), a visually identified fovea\u2010like region, and in regions superior and inferior to the optic nerve head (ONH). Measurements were analyzed using a multilevel regression.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>The CC was visible in over 90% of scanlines from dogs and cats. The ONL was consistently thinnest in the fovea\u2010like region. The outer retina (ELM\u2010RPE and ELM\u2010CC) was thickest within the AC compared with superior and inferior to the ONH in dogs and cats (<jats:italic>p<\/jats:italic>\u2009&lt;\u2009.001 for all comparisons).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>The CC appears a valid, albeit less than ideal outer retinal boundary marker in tapetal species. The AC can be objectively differentiated from the surrounding retina on SD\u2010OCT images of dogs and cats; a fovea\u2010like region was identified in dogs and its presence was suggested in cats. These findings allow targeted imaging and image evaluation of these regions of retinal specialization.<\/jats:p><\/jats:sec>","DOI":"10.1111\/vop.12989","type":"journal-article","created":{"date-parts":[[2022,5,25]],"date-time":"2022-05-25T07:55:29Z","timestamp":1653465329000},"page":"122-135","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":5,"title":["Outer retinal thickness and visibility of the choriocapillaris in four distinct retinal regions imaged with spectral domain optical coherence tomography in dogs and cats"],"prefix":"10.1111","volume":"25","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-2852-897X","authenticated-orcid":false,"given":"Elisa","family":"Mischi","sequence":"first","affiliation":[{"name":"Ophthalmology Section, Equine Department, Vetsuisse Faculty University of Zurich Zurich 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