{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,28]],"date-time":"2026-10-28T15:05:34Z","timestamp":1793199934357,"version":"4.5.0"},"reference-count":41,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2022,5,22]],"date-time":"2022-05-22T00:00:00Z","timestamp":1653177600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Veterinary Ophthalmology"],"published-print":{"date-parts":[[2022,9]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Purpose<\/jats:title>\n                    <jats:p>To describe the prevalence of ocular diseases in Sphynx cats, and compare disease characteristics with other feline breeds.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>Medical records of Sphynx cats presented to an ophthalmology referral center between 1\/2012 and 4\/2021 were examined. Cats of other breeds examined during the same period served as controls.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      One hundred ten Sphynx cats were examined during the study period, diagnosed with corneal sequestrum (\n                      <jats:italic>n<\/jats:italic>\n                      \u00a0=\u200942 cats), lower eyelid entropion (\n                      <jats:italic>n<\/jats:italic>\n                      \u00a0=\u200925), presumed herpetic keratoconjunctivitis (\n                      <jats:italic>n<\/jats:italic>\n                      \u00a0=\u200919), conjunctivitis (\n                      <jats:italic>n<\/jats:italic>\n                      \u00a0=\u20097), corneal ulcers (\n                      <jats:italic>n<\/jats:italic>\n                      \u00a0=\u20096), nasolacrimal duct atresia\/obstruction (\n                      <jats:italic>n<\/jats:italic>\n                      \u00a0=\u20096), corneal dystrophy (\n                      <jats:italic>n<\/jats:italic>\n                      \u00a0=\u20093), eosinophilic keratitis (\n                      <jats:italic>n<\/jats:italic>\n                      \u00a0=\u20092), uveitis (\n                      <jats:italic>n<\/jats:italic>\n                      \u00a0=\u20092), non\u2010ulcerative keratitis (\n                      <jats:italic>n<\/jats:italic>\n                      \u00a0=\u20091), and cataract (\n                      <jats:italic>n<\/jats:italic>\n                      \u00a0=\u20091). Corneal sequestrum was significantly more common in Sphynx versus non\u2010Sphynx cats (odds ratio\u00a0=\u00a08.0, 95% CI\u00a0=\u00a05.3\u201312.2,\n                      <jats:italic>p<\/jats:italic>\n                      \u00a0&lt;\u2009.001), and age of diagnosis was significantly younger in Sphynx cats (2.0\u00a0\u00b1\u20091.5\u2009years vs. 5.9\u00a0\u00b1\u20094.0\u2009years,\n                      <jats:italic>p<\/jats:italic>\n                      \u00a0&lt;\u2009.001). Corneal sequestrum recurrence was noted in 19.4% Sphynx eyes and 6.4% non\u2010Sphynx eyes undergoing surgery (\n                      <jats:italic>p<\/jats:italic>\n                      \u00a0=\u2009.015). Lower eyelid entropion\u2014most often bilateral (80%)\u2014was significantly more common in Sphynx versus non\u2010Sphynx cats (odds ratio\u00a0=\u00a04.1, 95% CI\u00a0=\u00a02.3\u20137.1,\n                      <jats:italic>p<\/jats:italic>\n                      \u00a0&lt;\u2009.001), and age of diagnosis was significantly younger in Sphynx cats (0.9\u00a0\u00b1\u20091.4\u2009years vs. 3.5\u00a0\u00b1\u20093.3\u2009years,\n                      <jats:italic>p<\/jats:italic>\n                      \u00a0&lt;\u2009.005).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>Corneal sequestrum and entropion were overrepresented and diagnosed at an earlier age in Sphynx cats when compared with the general feline population. Given the high prevalence, early age of onset, and relatively high recurrence of corneal sequestrum in Sphynx cats, further studies are warranted to better understand etiopathogenesis and preferred therapies.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/vop.12994","type":"journal-article","created":{"date-parts":[[2022,5,22]],"date-time":"2022-05-22T03:29:40Z","timestamp":1653190180000},"page":"367-375","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":7,"title":["Prevalence and characteristics of ocular diseases in Sphynx cats: A retrospective assessment (2012\u20132021) and comparison with\n                    <scp>non\u2010Sphynx<\/scp>\n                    cats"],"prefix":"10.1111","volume":"25","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-6400-2668","authenticated-orcid":false,"given":"Havi","family":"Sarfaty","sequence":"first","affiliation":[{"name":"EYECARE Clinic Yahud\u2010Monoson 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