{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,17]],"date-time":"2026-09-17T15:11:31Z","timestamp":1789657891036,"version":"4.0.1"},"reference-count":35,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2022,8,12]],"date-time":"2022-08-12T00:00:00Z","timestamp":1660262400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Veterinary Ophthalmology"],"published-print":{"date-parts":[[2023,11]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Objectives<\/jats:title><jats:p>To describe the most common ocular lesions and demonstrate the frequency of ophthalmic involvement in a group of cats with systemic sporotrichosis.<\/jats:p><\/jats:sec><jats:sec><jats:title>Animals Studied<\/jats:title><jats:p>Two hundred seventy\u2010four cats diagnosed with systemic sporotrichosis. The inclusion criteria included previous positive cytopathological examination, histopathological examination, or fungal culture.<\/jats:p><\/jats:sec><jats:sec><jats:title>Procedures<\/jats:title><jats:p>In a prospective case\u2013control study, 274 cats diagnosed with systemic sporotrichosis underwent ophthalmic evaluation and received treatment for systemic sporotrichosis. Of these animals, 63 had ocular abnormalities which were recorded, and conjunctivitis was scored from 0 to 5. Diagnostic techniques utilized included fungal culture, as well as cytopathological (10 eyes; 10 cats), and histopathological examination of the palpebral conjunctiva and eyes (2 eyes).<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Cytopathological and histopathological examination of the conjunctiva, as well as fungal culture, proved to be important tests for the detection of<jats:italic>Sporothrix sp<\/jats:italic>. Five cats without the evidence of ophthalmic abnormalities also had a positive fungal culture. The identified ocular lesions in animals with systemic sporotrichosis included increased serous discharge (79 eyes; 53 cats), blepharoconjunctivitis (33 eyes; 25 cats), conjunctivitis (39 eyes, 20 cats), blepharitis (9 eyes; 8 cats), uveitis (5 eyes; 3 cats), and Florida keratopathy\u2010like lesions (2 eyes; 1 cat).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>Sporotrichosis should be considered a differential diagnosis for conjunctivitis and blepharoconjunctivitis, especially in endemic areas. Fungal culture and cytopathology of ocular discharge and histopathological examinations of the conjunctiva are important for the diagnosis of ophthalmic sporotrichosis, although not all cats underwent laboratory testing in this study. Ocular discharge could be a source of contagion transmission.<\/jats:p><\/jats:sec>","DOI":"10.1111\/vop.13019","type":"journal-article","created":{"date-parts":[[2022,8,12]],"date-time":"2022-08-12T17:25:31Z","timestamp":1660325131000},"page":"476-488","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":5,"title":["Ocular lesions in cats diagnosed with systemic sporotrichosis"],"prefix":"10.1111","volume":"26","author":[{"given":"Henrique M.","family":"Freitas","sequence":"first","affiliation":[{"name":"Veterinary Medicine Department, Comparative Ophthalmology Laboratory (LABOCO Federal University of Paran\u00e1 (UFPR) Curitiba Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Renata C. B.","family":"da Rocha","sequence":"additional","affiliation":[{"name":"School of Life Sciences Pontifical Catholic University of Paran\u00e1 (PUCPR) Curitiba Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marconi R.","family":"de Farias","sequence":"additional","affiliation":[{"name":"School of Life Sciences Pontifical Catholic University of Paran\u00e1 (PUCPR) Curitiba Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bret A.","family":"Moore","sequence":"additional","affiliation":[{"name":"Department of Small Animal Clinical Sciences, College of Veterinary Medicine University of Florida (UF) Gainesville Florida USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3933-8864","authenticated-orcid":false,"given":"Fabiano","family":"Montiani\u2010Ferreira","sequence":"additional","affiliation":[{"name":"Veterinary Medicine Department, Comparative Ophthalmology Laboratory (LABOCO Federal University of Paran\u00e1 (UFPR) Curitiba Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2022,8,12]]},"reference":[{"key":"e_1_2_6_2_1","doi-asserted-by":"publisher","DOI":"10.1046\/j.1365-4362.2003.01813.x"},{"key":"e_1_2_6_3_1","doi-asserted-by":"publisher","DOI":"10.1128\/JCM.00808-07"},{"key":"e_1_2_6_4_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.ppat.1006077"},{"key":"e_1_2_6_5_1","doi-asserted-by":"publisher","DOI":"10.1097\/QCO.0b013e3282f44c52"},{"key":"e_1_2_6_6_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1863-2378.2008.01227.x"},{"key":"e_1_2_6_7_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pntd.0002281"},{"key":"e_1_2_6_8_1","doi-asserted-by":"publisher","DOI":"10.1093\/mmy\/myx103"},{"key":"e_1_2_6_9_1","doi-asserted-by":"publisher","DOI":"10.1097\/01.ico.0000151504.26695.3e"},{"key":"e_1_2_6_10_1","doi-asserted-by":"publisher","DOI":"10.22456\/1679-9216.17283"},{"key":"e_1_2_6_11_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ajoc.2017.09.005"},{"key":"e_1_2_6_12_1","doi-asserted-by":"publisher","DOI":"10.1111\/vop.12865"},{"key":"e_1_2_6_13_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jfms.2010.06.001"},{"key":"e_1_2_6_14_1","doi-asserted-by":"publisher","DOI":"10.1128\/jcm.29.6.1106-1113.1991"},{"key":"e_1_2_6_15_1","doi-asserted-by":"publisher","DOI":"10.1128\/CMR.00007-11"},{"issue":"3","key":"e_1_2_6_16_1","first-page":"90","article-title":"Aspectos epidemiol\u00f3gicos da esporotricose felina no munic\u00edpio de Curitiba, estado do Paran\u00e1, Brasil, entre 2014 e 2016","volume":"15","author":"Runcos LHE","year":"2017","journal-title":"Revista MV&Z"},{"issue":"1","key":"e_1_2_6_17_1","first-page":"1","article-title":"Feline sporotrichosis due to Sporothrix brasiliensis: an emerging animal infection in S\u00e3o Paulo","volume":"10","author":"Montenegro H","year":"2014","journal-title":"Brazil BMC Vet Res"},{"key":"e_1_2_6_18_1","doi-asserted-by":"publisher","DOI":"10.1007\/s42770-020-00365-3"},{"key":"e_1_2_6_19_1","doi-asserted-by":"publisher","DOI":"10.2460\/javma.2004.224.1623"},{"key":"e_1_2_6_20_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0168-1591(00)00094-0"},{"key":"e_1_2_6_21_1","doi-asserted-by":"publisher","DOI":"10.1023\/A:1014449621732"},{"key":"e_1_2_6_22_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jfms.2009.01.012"},{"issue":"1","key":"e_1_2_6_23_1","doi-asserted-by":"crossref","first-page":"7","DOI":"10.22456\/1679-9216.89399","article-title":"Sodium iodide: an alternative treatment option for feline sporotrichosis?","volume":"46","author":"Carvalho BW","year":"2018","journal-title":"Acta Sci Vet"},{"key":"e_1_2_6_24_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41598-018-27447-5"},{"key":"e_1_2_6_25_1","doi-asserted-by":"publisher","DOI":"10.1292\/jvms.64.215"},{"key":"e_1_2_6_26_1","doi-asserted-by":"publisher","DOI":"10.11606\/issn.1678-4456.bjvras.2017.104588"},{"key":"e_1_2_6_27_1","first-page":"1476","volume-title":"Veterinary Ophthalmology","author":"Gelatt KN","year":"2013"},{"key":"e_1_2_6_28_1","doi-asserted-by":"publisher","DOI":"10.1186\/s12917-020-02677-w"},{"key":"e_1_2_6_29_1","doi-asserted-by":"publisher","DOI":"10.1136\/bjophthalmol-2017-310581"},{"key":"e_1_2_6_30_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.joco.2019.01.006"},{"key":"e_1_2_6_31_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0207644"},{"key":"e_1_2_6_32_1","doi-asserted-by":"publisher","DOI":"10.1111\/vop.12898"},{"issue":"7","key":"e_1_2_6_33_1","doi-asserted-by":"crossref","first-page":"1271","DOI":"10.2460\/javma.1996.209.07.1271","article-title":"Ocular blastomycosis in dogs: 73 cases, 108 eyes (1985\u20101993)","volume":"209","author":"Bloom JD","year":"1996","journal-title":"J Am Vet Med Assoc"},{"key":"e_1_2_6_34_1","doi-asserted-by":"publisher","DOI":"10.1053\/j.ctsap.2005.07.004"},{"key":"e_1_2_6_35_1","doi-asserted-by":"publisher","DOI":"10.1111\/vop.12811"},{"key":"e_1_2_6_36_1","doi-asserted-by":"publisher","DOI":"10.1097\/ICB.0000000000000290"}],"container-title":["Veterinary Ophthalmology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/vop.13019","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1111\/vop.13019","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/vop.13019","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,10,1]],"date-time":"2024-10-01T13:07:24Z","timestamp":1727788044000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/vop.13019"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,8,12]]},"references-count":35,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2023,11]]}},"alternative-id":["10.1111\/vop.13019"],"URL":"https:\/\/doi.org\/10.1111\/vop.13019","archive":["Portico"],"relation":{},"ISSN":["1463-5216","1463-5224"],"issn-type":[{"value":"1463-5216","type":"print"},{"value":"1463-5224","type":"electronic"}],"subject":[],"published":{"date-parts":[[2022,8,12]]},"assertion":[{"value":"2022-02-27","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2022-08-05","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2022-08-12","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}