{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,19]],"date-time":"2026-05-19T14:05:27Z","timestamp":1779199527000,"version":"3.51.4"},"reference-count":65,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2022,9,9]],"date-time":"2022-09-09T00:00:00Z","timestamp":1662681600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Veterinary Ophthalmology"],"published-print":{"date-parts":[[2022,11]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Purpose<\/jats:title><jats:p>To evaluate bacterial contamination of conjunctiva and aqueous humor in dogs undergoing phacoemulsification following asepsis with 0.5% povidone iodine and determine the influence of intravenous antibiotics on outcome of contamination.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Client\u2010owned dogs were prospectively enrolled and randomly assigned to a control group, receiving 22\u2009mg\/kg intravenous cefazolin at induction prior to sampling, or experimental group receiving no antibiotic prior to sampling, masked to the surgeon. Dogs receiving antimicrobials in the pre\u2010operative period were excluded. Asepsis was performed on all operated eyes using 0.5% iodine with minimum 3\u00a0min contact time at induction of anesthesia and repeated before surgery. A conjunctival swab and aqueous humor sample were collected prior to incision and following incision closure, respectively. Samples were submitted for aerobic and anaerobic bacterial culture and susceptibility.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Seventy\u2010one eyes of 42 dogs were included. Median age was 9\u2009years. Thirty\u2010nine and 32\/71 eyes received intravenous cefazolin and no antibiotic, respectively. Median procedure time was 40\u2009min per eye. Conjunctival cultures were positive in 6 eyes (8.5%):<jats:italic>Serratia marcescens<\/jats:italic>(5 eyes) and<jats:italic>Cutibacterium acnes<\/jats:italic>(1 eye). Aqueous humor cultures were positive in 5 eyes (7.0%):<jats:italic>S.\u00a0marcescens<\/jats:italic>(2 eyes),<jats:italic>Pseudomonas aeruginosa<\/jats:italic>(2 eyes),<jats:italic>Staphylococcus pseudointermedius<\/jats:italic>(1 eye). Prevalence of positive culture did not differ between groups (<jats:italic>p<\/jats:italic>\u00a0=\u00a0.74), order of eyes for bilateral procedures (<jats:italic>p<\/jats:italic>\u00a0=\u00a0.74) and diabetic status (<jats:italic>p<\/jats:italic>\u00a0=\u00a01).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>Bacterial contamination of the conjunctiva and aqueous humor was present in 8.5% and 7.0% of dogs undergoing phacoemulsification after asepsis. Lack of IV cefazolin was not significantly associated with positive culture.<\/jats:p><\/jats:sec>","DOI":"10.1111\/vop.13023","type":"journal-article","created":{"date-parts":[[2022,9,9]],"date-time":"2022-09-09T20:57:46Z","timestamp":1662757066000},"page":"434-446","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":5,"title":["Prospective evaluation of the prevalence of conjunctival and intraocular bacteria in dogs undergoing phacoemulsification following a standardized aseptic preparation with 0.5% povidone iodine"],"prefix":"10.1111","volume":"25","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-9195-1463","authenticated-orcid":false,"given":"Sarah M.","family":"Coall","sequence":"first","affiliation":[{"name":"Department of Ophthalmology Small Animal Specialist Hospital Sydney New South Wales Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Allyson 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