{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,5,14]],"date-time":"2025-05-14T02:07:42Z","timestamp":1747188462720,"version":"3.40.5"},"reference-count":19,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2022,11,22]],"date-time":"2022-11-22T00:00:00Z","timestamp":1669075200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Veterinary Ophthalmology"],"published-print":{"date-parts":[[2023,1]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>A 6\u2010year\u2010old miniature Shetland pony mare was referred for evaluation of a left corneal mass, which developed from the healing tissue of a corneal traumatic ulceration that had occurred 4\u2009weeks previously. On gross examination, a spherical, smooth\u2010surfaced, and pink\u2010colored lesion of about 1\u00a0cm in diameter was protruding from the left palpebral fissure. Ophthalmic examination revealed that it was attached to the scar tissue of the cornea, and that one <jats:italic>corpora nigra<\/jats:italic> was adherent to the posterior face of corneal wounded area, without sign of uveitis. The remainder of the ophthalmic examination was unremarkable. The mass was excised, and cryotherapy was used as an adjunctive therapy. Histopathology of the resected mass was consistent with a pyogenic granuloma on the basis of radially oriented proliferating capillaries, embedded in immature granulation tissue containing an infiltrate of neutrophils, plasma cells and eosinophils. There were no histological features of malignancy. 2\u2009months after surgery, the ventral part of the fibrotic corneal scar was slightly raised by a pink tissue, suggesting possible recurrence of the initial lesion. A second cryotherapy was performed over the leukoma area. No recurrence has been noted for a follow\u2010up period of more than 25\u2009months. Pyogenic granuloma is a benign proliferative fibrovascular response that typically develops after trauma or surgery. Corneal involvement is rare in humans, and to the authors' knowledge has never been documented in veterinary ophthalmology.<\/jats:p>","DOI":"10.1111\/vop.13041","type":"journal-article","created":{"date-parts":[[2022,11,22]],"date-time":"2022-11-22T17:14:31Z","timestamp":1669137271000},"page":"62-70","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Pyogenic granuloma of the cornea in a pony: Uncommon complication of corneal wound healing"],"prefix":"10.1111","volume":"26","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-5535-7435","authenticated-orcid":false,"given":"Alain","family":"Regnier","sequence":"first","affiliation":[{"name":"CHUVAC Universit\u00e9 de Toulouse, ENVT  Toulouse France"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Clara","family":"Landrevie","sequence":"additional","affiliation":[{"name":"CHUVAC Universit\u00e9 de Toulouse, ENVT  Toulouse France"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Marie\u2010Claire","family":"Robin","sequence":"additional","affiliation":[{"name":"CHUVAC Universit\u00e9 de Toulouse, ENVT  Toulouse France"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Delphine","family":"Einsweiler","sequence":"additional","affiliation":[{"name":"Vet Equid  Servian France"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0426-4957","authenticated-orcid":false,"given":"Jean\u2010Yves","family":"Douet","sequence":"additional","affiliation":[{"name":"CHUVAC Universit\u00e9 de Toulouse, ENVT  Toulouse France"},{"name":"IHAP Universit\u00e9 de Toulouse, INRAE, ENVT  Toulouse France"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8723-5472","authenticated-orcid":false,"given":"Isabelle","family":"Raymond\u2010Letron","sequence":"additional","affiliation":[{"name":"LabHPEC Universit\u00e9 de Toulouse, ENVT  Toulouse France"},{"name":"Institut Restore Universit\u00e9 de Toulouse, CNRS U\u20105070, EFS, ENVT, Inserm U1031  Toulouse France"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2022,11,22]]},"reference":[{"key":"e_1_2_5_2_1","first-page":"229","article-title":"Pyogenic granuloma","volume":"74","author":"Lin RL","year":"2004","journal-title":"Cutis"},{"key":"e_1_2_5_3_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1440-1827.2005.01843.x"},{"key":"e_1_2_5_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.bjps.2006.10.018"},{"key":"e_1_2_5_5_1","first-page":"327","article-title":"Pyogenic granuloma of the eye and ocular adnexa: a study of 100 cases","volume":"87","author":"Ferry APA","year":"1989","journal-title":"Trans Am Ophthalmol Soc"},{"key":"e_1_2_5_6_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1442-9071.1998.tb01541.x"},{"key":"e_1_2_5_7_1","first-page":"252","volume-title":"Equine Ophthalmology","author":"Brooks DE","year":"2017"},{"key":"e_1_2_5_8_1","doi-asserted-by":"publisher","DOI":"10.1016\/0039-6257(84)90204-2"},{"key":"e_1_2_5_9_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0161-6420(95)30809-3"},{"key":"e_1_2_5_10_1","doi-asserted-by":"publisher","DOI":"10.1007\/BF00695253"},{"key":"e_1_2_5_11_1","doi-asserted-by":"publisher","DOI":"10.1001\/archopht.1979.01020010260015"},{"key":"e_1_2_5_12_1","first-page":"39","article-title":"Pyogenic granuloma of the cornea: a case report","volume":"44","author":"Srinivasan S","year":"1996","journal-title":"Indian J Ophthalmol"},{"key":"e_1_2_5_13_1","doi-asserted-by":"publisher","DOI":"10.1001\/archopht.121.8.1197"},{"key":"e_1_2_5_14_1","doi-asserted-by":"publisher","DOI":"10.4314\/ejhs.v24i1.11"},{"key":"e_1_2_5_15_1","doi-asserted-by":"publisher","DOI":"10.1097\/00003226-199211000-00019"},{"key":"e_1_2_5_16_1","first-page":"156","volume-title":"Ophthalmic Pathology. 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